Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Looking at cancer drugs to help put the brakes on classic indicators of aging

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

A new research paper was published in Oncotarget's Volume 14 on May 19, 2023, entitled, "G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis."

23 May 2023

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Researchers from Rice University and Baylor College of Medicine are hoping a first-of-its-kind "glyco-immune" checkpoint inhibitor could be the key to stopping bone cancer metastasis for breast cancer survivors.

19 May 2023

Fatty liver promotes the spread of colorectal cancer to the liver

Investigators at Cedars-Sinai Cancer found that fatty liver, a condition closely associated with obesity, promotes the spread of colorectal cancer to the liver.

11 May 2023

Research sheds light on the early cellular events that give rise to pancreatic cancer

Discussions of cancer often stress the genetic mutations that drive disease by altering the normal function of cellular proteins.

11 May 2023

Johns Hopkins scientists get $35 million gift to study the biological roots of cancer metastasis

With a $35 million gift from researcher, philanthropist and race car driver Theodore Giovanis, scientists at Johns Hopkins Medicine will study the biological roots of the most fatal aspect of cancer: how it metastasizes, or spreads, through the body.

10 May 2023

Breast cancer tumors disrupt the development of an immune response to favor their own growth

Researchers at Baylor College of Medicine and collaborating institutions have identified a strategy cancerous tumors use to remotely disrupt the development of an immune response that could stop their growth.

5 May 2023

Study finds a pharmacological-based approach to revert immune escape of breast cancer cells

Freiburg researchers discover a mechanism by which cancer cells escape the immune system.

4 May 2023

Researchers develop a deep learning model to classify cancer cells by type

Cancer cells that initiate metastasis, or the spread of the disease from its primary location, are different from cancer cells that stay in the original tumor. Distinguishing metastasis-initiating cell types can determine the severity of cancer and help medical practitioners decide on a course of treatment.

2 May 2023

Inhibiting mitochondrial regulator ATAD3A could prevent head and neck cancer development

A new research perspective was published in Oncoscience (Volume 10) on April 4, 2023, entitled, "Mitochondrial regulator ATAD3A: a molecular determinant favoring head and neck cancer development."

28 Apr 2023

Unique treatment can eradicate pancreatic tumors while stopping cancer progression

A unique treatment combining radiation and immunotherapy can eradicate pancreatic tumors while stopping the cancer from spreading, according to a new study by researchers at the University of Colorado Cancer Center.

27 Apr 2023

Melanoma research unveils landscape of DNA and RNA alterations across multiple organs of metastasis

In a new translational study from UCLA Jonsson Comprehensive Cancer Center, researchers analyzed genetic changes in the organs of recently deceased patients to understand how metastatic cutaneous melanoma spreads in those who had initially benefited from precision therapies.

27 Apr 2023

Research develops unique delivery system to treat osteosarcoma

New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.

27 Apr 2023

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Researchers at the Johns Hopkins Kimmel Cancer Center identified a novel cell signaling pathway that potentially could be targeted in therapy for patients with aggressive pancreatic cancers.

24 Apr 2023

Sphere Fluidics begins work with partners on 3DSecret program to investigate mechanisms of metastasis in cancer

Sphere Fluidics announced its involvement in 3DSecret.

From Fluidic Sciences and Sphere Bio 24 Apr 2023

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

A recent study reveals that DCAF1 is overexpressed and phosphorylates EZH2 in colon cancer cells.

18 Apr 2023

Changes to tumor DNA can help predict cancer's next move

Knowing whether a tumor might grow or spread to other parts of a patient’s body could be key to survival – and now scientists are one step closer to unlocking the ability to predict just that.

13 Apr 2023

DPE analysis may help improve the diagnosis and management of colorectal cancer

A new editorial paper was published in Oncoscience (Volume 10) on March 23, 2023, entitled, "New method of clustering colorectal cancer patients using differential presence of exons (DPE) sequencing."

7 Apr 2023

New model can speed up the evaluation process for drugs used to combat cervical cancer

Researchers at Oregon State University have created a means of speeding up and improving the evaluation process for drugs used to combat cervical cancer.

31 Mar 2023

Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

Metastasis News and Research

Further Reading

Looking at cancer drugs to help put the brakes on classic indicators of aging

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

Researchers receive $2.3 million to continue development of a new ‘glyco-immune’ checkpoint inhibitor

Fatty liver promotes the spread of colorectal cancer to the liver

Research sheds light on the early cellular events that give rise to pancreatic cancer

Johns Hopkins scientists get $35 million gift to study the biological roots of cancer metastasis

Breast cancer tumors disrupt the development of an immune response to favor their own growth

Study finds a pharmacological-based approach to revert immune escape of breast cancer cells

Researchers develop a deep learning model to classify cancer cells by type

Inhibiting mitochondrial regulator ATAD3A could prevent head and neck cancer development

Unique treatment can eradicate pancreatic tumors while stopping cancer progression

Melanoma research unveils landscape of DNA and RNA alterations across multiple organs of metastasis

Research develops unique delivery system to treat osteosarcoma

Novel cell signaling pathway could be targeted against aggressive pancreatic cancers

Sphere Fluidics begins work with partners on 3DSecret program to investigate mechanisms of metastasis in cancer

Study reveals DCAF1 protein's role in colon cancer development through EZH2 phosphorylation

Changes to tumor DNA can help predict cancer's next move

DPE analysis may help improve the diagnosis and management of colorectal cancer

New model can speed up the evaluation process for drugs used to combat cervical cancer

Drugs to activate STING could help prevent cancer metastasis

Lab Matters host Harriet Gould on building a more connected lab community

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