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Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

Researchers from Japan discover that glucagon-like peptide-2 (GLP-2) analogs can deeply and beneficially reshape the intestinal environment.

27 Aug 2025

CURE GABA-A and Grann Pharmaceuticals announce global partnership to advance rare neurological therapies

CURE GABA-A (https://curegabaa.org/) is proud to announce a major new partnership with Grann Pharmaceuticals. CURE GABA-A is a nonprofit patient advocacy group founded by Monica Joanna Elnekaveh, mother to Eleanor Elnekaveh.

27 Aug 2025

Transcutaneous vagal nerve stimulation shows promise for gastrointestinal disorders

Imbalanced autonomic function, characterized by reduced vagal activity and sympathetic dominance, is increasingly recognized in various gastrointestinal (GI) disorders.

27 Aug 2025

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

GLP-1 receptor agonists are transforming obesity and diabetes care, but may reduce skeletal muscle mass, raising concerns about sarcopenic obesity. This comprehensive review explores the mechanisms, clinical implications, and mitigation strategies, including exercise, protein intake, and adjunct therapies.

26 Aug 2025

First comprehensive road map shows how the ovarian reserve forms in primates

UCLA scientists have developed the first comprehensive road map showing how the ovarian reserve forms in primates, providing crucial insights into women's health that could revolutionize treatments for infertility and hormonal disorders such as polycystic ovary syndrome, or PCOS.

26 Aug 2025

Mediterranean diet with lifestyle changes lowers diabetes risk by 31%

A Mediterranean-style diet, in combination with reduced caloric intake, moderate physical activity, and professional support for weight loss, may cut the risk of type 2 diabetes (T2D) by 31%, according to a new study co-authored by researchers at Harvard T.H. Chan School of Public Health.

25 Aug 2025

Shame linked to lower quality of life in people with gut disorders

Feelings of shame are linked to reduced quality of life - as shown by the first study to measure shame as a factor influencing the connection between chronic gastrointestinal disorders and mental health.

25 Aug 2025

Gut bacteria and insomnia influence each other in small but significant ways, study shows

Scientists used Mendelian randomisation to explore the two-way relationship between gut microbiota and insomnia, analyzing GWAS data from over 386,000 individuals and two major microbiome cohorts. The study found only limited taxa surviving strict correction, suggesting small but causal links that highlight the gut–brain axis in sleep health.

21 Aug 2025

Evidence review questions ketamine’s role in chronic pain treatment

A Cochrane review assessed ketamine and other NMDA receptor antagonists for chronic non-cancer pain. The evidence was low to very low certainty, showing no clear pain relief and potential adverse effects with intravenous ketamine.

21 Aug 2025

COVID-19 vaccine successes boosted hesitancy - can trust and equity restore immunization?

Researchers show that countries with higher initial COVID-19 vaccine acceptance also achieved stronger booster uptake, but trust and access remain decisive. The commentary warns that vaccine successes also fueled hesitancy, demanding structural reforms, clear communication, and proactive strategies to protect immunization.

21 Aug 2025

Boston University launches project to improve colonoscopy access for autistic adults

Boston University has been approved for a funding award through the Eugene Washington PCORI Engagement Award Program, an initiative of the Patient-Centered Outcomes Research Institute (PCORI).

21 Aug 2025

Genetic variants influencing vitamin D synthesis, metabolism, and transport

A Canadian review synthesizes genetic factors that influence vitamin D synthesis, metabolism, and transport, highlighting how polymorphisms affect circulating levels. It also explores how gene-environment interactions shape individual responses to supplementation and sunlight.

20 Aug 2025

Metabolic syndrome linked to higher risk of Parkinson's disease

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of Parkinson's disease, according to a study published on August 20, 2025, in Neurology, the medical journal of the American Academy of Neurology.

20 Aug 2025

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

In a new study led by the University of Pennsylvania School of Veterinary Medicine (Penn Vet) and Children's Hospital of Philadelphia (CHOP), researchers found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with 22qDS.

20 Aug 2025

Ciliary Hedgehog signaling controls the fate of fat precursor cells

Too much fat can be unhealthy: how fat cells, so-called adipocytes, develop, is crucial for the function of the fat tissue.

20 Aug 2025

COVID-19 accelerates vascular aging in women

Research shows COVID-19 accelerates vascular aging, especially in women, with implications for long-term cardiovascular health and recovery strategies.

20 Aug 2025

Low FODMAP diet increases GLP-1 and relieves IBS symptoms

This study reveals that a low FODMAP diet alleviates IBS symptoms and increases GLP-1 levels, suggesting new avenues for dietary interventions in gut health.

20 Aug 2025

Researchers call for comprehensive menstrual education in British schools

Teaching about periods in schools is still too focused on basic biological facts with insufficient information around how menstruation can affect a woman's mood and wellbeing, problems associated with menstrual bleeding and the impact on physical and academic performance, concludes a new study by UCL (University College London) researchers.

20 Aug 2025

COVID-19 ages arteries prematurely with women most affected

COVID-19 may leave arteries biologically “older,” with women showing more persistent stiffness and symptom links than men. Findings from the large CARTESIAN cohort suggest this vascular aging effect is partly reversible over time.

19 Aug 2025

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Texas Children's is pleased to announce that a three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency.

19 Aug 2025

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Syndrome News and Research

Longitudinal study reveals how GLP-2 analog therapy transforms the intestinal environment

CURE GABA-A and Grann Pharmaceuticals announce global partnership to advance rare neurological therapies

Transcutaneous vagal nerve stimulation shows promise for gastrointestinal disorders

Do GLP-1 drugs shrink your muscles? New study explains the risks and what to do

First comprehensive road map shows how the ovarian reserve forms in primates

Mediterranean diet with lifestyle changes lowers diabetes risk by 31%

Shame linked to lower quality of life in people with gut disorders

Gut bacteria and insomnia influence each other in small but significant ways, study shows

Evidence review questions ketamine’s role in chronic pain treatment

COVID-19 vaccine successes boosted hesitancy - can trust and equity restore immunization?

Boston University launches project to improve colonoscopy access for autistic adults

Genetic variants influencing vitamin D synthesis, metabolism, and transport

Metabolic syndrome linked to higher risk of Parkinson's disease

Mitochondrial dysfunction in the blood-brain barrier may contribute to neuropsychiatric disease in 22qDS

Ciliary Hedgehog signaling controls the fate of fat precursor cells

COVID-19 accelerates vascular aging in women

Low FODMAP diet increases GLP-1 and relieves IBS symptoms

Researchers call for comprehensive menstrual education in British schools

COVID-19 ages arteries prematurely with women most affected

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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