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Harnessing power of CRISPR to control behavior of DNA-responsive materials

The CRISPR-Cas system has become the go-to tool for researchers who study genes in an ever-growing list of organisms, and is being used to develop new gene therapies that potentially can correct a defect at a single nucleotide position of the vast reaches of the genome.

23 Aug 2019

Study finds genetic links to childhood obesity across different ethnicities

An international team of researchers who analyzed data across multiple ethnicities has produced the largest genetic study to date associated with common childhood obesity.

22 Aug 2019

'Kissing loops' in lncRNA essential for tumor suppressor function

Human cells - like those of many other organisms - have developed mechanisms to protect us from cancer.

22 Aug 2019

Swallowable balloon device for early detection of Barrett's esophagus receives FDA 510K clearance

Investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center developed the test for early detection of Barrett's esophagus that offers promise for preventing deaths from esophageal adenocarcinoma.

21 Aug 2019

Protein present in telomeres shows global action on genome which influences pleuripotency

Pluripotent cells can give rise to all cells of the body, a power that researchers are eager to control because it opens the door to regenerative medicine and organ culture for transplants.

21 Aug 2019

Geneticists prove therapeutic effects of probiotics on vaginal health

Scientists have found strong evidence that three genes from Lactobacillus species can mediate adhesion to the vaginal epithelium.

20 Aug 2019

Researchers develop new gene editing system that could be used for anticancer immunotherapy

Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology announced that they have developed a new gene-editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with the immune system expressed on the surface of lymphoma cells and activation of cytotoxic T lymphocyte, based on the results of joint research conducted with Prof. Seokmann Hong and his group at Sejong University.

20 Aug 2019

Study provides new insight into regional survival differences in glioblastoma

A team of researchers from Osaka University, in cooperation with the Institute for Clinical Research and medical institutes participating in the Kansai Molecular Diagnosis Network for CNS Tumors, conducted the largest-ever retrospective cohort study for Japanese patients with glioblastoma, proposing an underlying prognosis biomarker responsible for the survival difference between two cohorts: an original Japanese cohort and a dataset from The Cancer Genome Atlas.

19 Aug 2019

Researchers find biological system that manages cells' response to opioid drug exposure

A team at Scripps Research in Florida has discovered a biological system that manages cells' response to opioid drug exposure. The unexpected discovery offers new ideas for improving the safety of the one of the most effective, and most abused, group of pain medications.

19 Aug 2019

Molecular mechanism of enterovirus infection uncovered

Researchers from the Nanoscience Center at the University of Jyväskylä in collaboration with those at the University of Helsinki have found that body proteins called albumin and certain ions within the attacked host cells can affect the genetic workings of enteroviruses and enhance their infection.

19 Aug 2019

Research reveals physiological events leading to successful enterovirus infection

Enteroviruses are one of the most common human pathogens leading to high number of acute and chronic infections worldwide.

19 Aug 2019

Mortality risk from yellow fever can be identified sooner

Approximately ten out of every 100 people who are bitten by mosquitos infected by the yellow fever virus develop symptoms of the disease. Although most infected people do not develop the disease, it is lethal to approximately 40% of those who do.

14 Aug 2019

Researchers identify new transmembrane protein as chloride ion channel

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems.

14 Aug 2019

Study shows how cervicovaginal microbiome can elicit resistance to chlamydia

The vaginal microbiome is believed to protect women against Chlamydia trachomatis, the etiological agent of the most prevalent sexually transmitted infections in developed countries.

13 Aug 2019

Study unearths evolutionary history of antibiotic production and resistance

A study from McMaster University has unearthed new details about the evolutionary history of both antibiotic production and resistance and dates their co-emergence as far back as 350 to 500 million years.

13 Aug 2019

A newly-emerging species of C. difficile highly adapted to spread in hospitals

Scientists have discovered that the gut-infecting bacterium Clostridium difficile is evolving into two separate species, with one group highly adapted to spread in hospitals.

12 Aug 2019

UAMS Myeloma Center receives $542,486 grant from Leukemia & Lymphoma Society

Brian Walker, Ph.D., with the Myeloma Center at the University of Arkansas for Medical Sciences has received a $542,486, three-year grant from the Leukemia & Lymphoma Society to look at changes in the DNA sequence that effects the development and advancement of multiple myeloma, a cancer of plasma cells in the blood.

12 Aug 2019

Genome News and Research

Harnessing power of CRISPR to control behavior of DNA-responsive materials

Study finds genetic links to childhood obesity across different ethnicities

'Kissing loops' in lncRNA essential for tumor suppressor function

Swallowable balloon device for early detection of Barrett's esophagus receives FDA 510K clearance

Protein present in telomeres shows global action on genome which influences pleuripotency

Geneticists prove therapeutic effects of probiotics on vaginal health

Researchers develop new gene editing system that could be used for anticancer immunotherapy

Study provides new insight into regional survival differences in glioblastoma

Researchers find biological system that manages cells' response to opioid drug exposure

Molecular mechanism of enterovirus infection uncovered

Research reveals physiological events leading to successful enterovirus infection

Mortality risk from yellow fever can be identified sooner

Researchers identify new transmembrane protein as chloride ion channel

Study shows how cervicovaginal microbiome can elicit resistance to chlamydia

Study unearths evolutionary history of antibiotic production and resistance

A newly-emerging species of C. difficile highly adapted to spread in hospitals

UAMS Myeloma Center receives $542,486 grant from Leukemia & Lymphoma Society

New discovery could help doctors identify children at risk for Wilms’ tumor relapse

UCLA-led researchers identify 69 genes that increase risk for autism spectrum disorder

Neuronal gene malfunction is behind seizures associated with long QT syndrome, study suggests

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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