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Gene modulation goes wireless hacking the "boss gene"

Researchers from the University at Buffalo have successfully used technology to wirelessly tweak the functioning of a gene FGFR1. This gene is vital in the growth of embryos into adults. Their experiments were successful in the lab grown brain tissues and shows potential in therapeutics.

16 Jul 2019

EMBL study reveals uncoupling between chromatin topology and gene expression

Molecular biologists long thought that domains in the genome’s 3D organization control how genes are expressed.

16 Jul 2019

HIV therapy leaves unrepaired holes in the immune system's wall of defense

If they don't receive antiretroviral therapy (ART), most HIV patients see a progressive weakening of their immune system.

16 Jul 2019

New study identifies eight genetic variants associated with anorexia nervosa

A new large-scale genome-wide association study published in Nature Genetics, has identified eight genetic variants significantly associated with anorexia nervosa; and the research shows that the origins of this serious disorder appear to be both metabolic and psychiatric.

16 Jul 2019

Scientists discover hundreds of protein-pairs through coevolution study

Scientists have discovered hundreds of new protein-protein interactions by looking for co-evolution in some residues of aligned protein sequences.

15 Jul 2019

Research sheds light on sun-induced DNA damage and repair

It is a well known fact that the sun’s ultraviolet rays can damage the skin. Now, a new study sheds light on what happens after DNA damage occurs, and how the body initiates repair.

15 Jul 2019

Nanoparticles used to deliver CRISPR gene editing tools into the cell

Researchers from Tufts University and the Chinese Academy of Sciences have developed a novel method to effectively deliver the CRISPR/Cas9 (clustered regularly interspaced short palindromic repeat (CRISPR) associated protein 9) gene editing tools into the liver for genetic studies.

15 Jul 2019

Researchers discover gene linked to healthy aging in worms

People with the same lifespan do not necessarily have the same quality of life. As we live longer, extending quality of life -- "healthspan" -- is gaining importance.

12 Jul 2019

New therapeutic food boosts key growth-promoting gut microbes in malnourished children

A new type of therapeutic food, specifically designed to repair the gut microbiomes of malnourished children, is superior to standard therapy in an initial clinical trial conducted in Bangladesh.

12 Jul 2019

Ancient epigenetic change deactivates some genes linked to cancer

An epigenetic change, a form of DNA control, that deactivates some genes linked to cancer late in human development has been conserved for more than 400 million years, new research led by the Garvan Institute of Medical Research suggests.

11 Jul 2019

Researchers explain how 'viral' agents of neurological diseases ended up in our DNA

What if the missing ‘environmental’ factor in some of our deadliest neurological diseases were really written in our genome?

11 Jul 2019

Research reveals genetic cause of deadly digestive disease in children

Nearly 10 years ago, a group of Israeli clinical researchers emailed Lawrence Berkeley National Laboratory (Berkeley Lab) geneticist Len Pennacchio to ask for his team's help in solving the mystery of a rare inherited disease that caused extreme, and sometimes fatal, chronic diarrhea in children.

11 Jul 2019

UCR scientists decode genome of black-eyed peas

UC Riverside scientists have decoded the genome of black-eyed peas, offering hope for feeding Earth's expanding population, especially as the climate changes.

10 Jul 2019

New gene-editing protocol allows perfect mutation-effect matching

Geneticists have long awaited the ability to simply knock out or add a single gene here and there, as desired, with accuracy and efficiency, and then study the exact consequences caused by the loss or addition of that genetic information.

9 Jul 2019

Virus killing protein could be the real antiviral hero finds study

Researchers have identified a protein that can kill viruses and it forms the missing clue to the natural antiviral mechanism of the body that can target the viruses based on their genetic patterns. This newly identified protein is called KHNYN.

9 Jul 2019

How electrical stimulation promotes wound healing

Scientists have known for decades that electrical stimulation promotes healing of chronic wounds, such as diabetic ulcers and bedsores, but how it happens has been a mystery-until now.

9 Jul 2019

New research uncovers mechanism behind the newest generation of cancer drugs

New research that uncovers the mechanism behind the newest generation of cancer drugs is opening the door for better targeted therapy.

9 Jul 2019

Does genetic testing affect psychosocial health?

A recent report from the Hastings Center brings out evidence for the first time that knowing about one’s increased genetic risk for diseases such as obesity, cancer and Alzheimer’s can actually alter one’s functioning negatively.

9 Jul 2019

Using NMR to Study Protein Structure, Dynamics and Mechanisms

Fábio Almeida describes how NMR can be used to elucidate protein structure and how this data can be applied to human disease.

From Bruker BioSpin Group 4 Jul 2019

Study reveals first complete wiring diagram of an animal's nervous system

In a study published online today in Nature, researchers at Albert Einstein College of Medicine describe the first complete wiring diagram of the nervous system of an animal, the roundworm Caenorhabditis elegans, used by scientists worldwide as a model organism.

4 Jul 2019