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How comorbidities affect SARS-CoV-2 viral entry

Almost from the start of the current COVID-19 pandemic, it has become clear that individuals suffering from other medical conditions like diabetes, cardiovascular disease, and lung disease are far more likely to contract the infection and to have a poorer outcome.

28 May 2020

Face masks essential in combating asymptomatic spread of SARS-CoV-2 aerosols and droplets

The coronavirus disease (COVID-19) occurs through the transmission of droplets and aerosols from infected people through speaking, breathing, coughing, and sneezing. Wearing masks can reduce the airborne transmission of the novel coronavirus, a new study finds. The research is published in the journal Science.

28 May 2020

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

An international research team has for the first time obtained the structure of the light-sensitive sodium-pumping KR2 protein in its active state.

28 May 2020

Stem cell treatments elicit full structural regeneration of the sun-aged skin

For a while now, some plastic surgeons have been using stem cells to treat aging, sun-damaged skin. But while they've been getting good results, it's been unclear exactly how these treatments - using adult stem cells harvested from the patient's own body - work to rejuvenate "photoaged" facial skin.

28 May 2020

Research finds delayed treatment for ischemic stroke patients during COVID-19 pandemic

New research published today in the Journal of NeuroInterventional Surgery shows ischemic stroke patients are arriving to hospitals and treatment centers an average of 160 minutes later during the COVID-19 pandemic, as compared with a similar timeframe in 2019.

28 May 2020

Ludwig Cancer Research study profiles immune landscape of brain tumors

A Ludwig Cancer Research study has profiled, in a sweeping comparative analysis, the distinct immune landscapes of tumors that arise in the brain, or gliomas, and those that metastasize to the organ from the lungs, breast and skin.

28 May 2020

Dual-pathway approach can lead to better outcomes in patients with heart stents

Pairing a blood-thinning drug with aspirin daily for patients who have an angioplasty with a stent can contribute to better health outcomes, including lower risk of death, than aspirin alone, according to a recent study by cardiologists at the University of Alberta and Mazankowski Alberta Heart Institute.

28 May 2020

Brazilian researchers design low-cost mechanical ventilators

A group of researchers at the University of São Paulo's Engineering School (POLI-USP) in Brazil have developed a mechanical ventilator that costs only approximately 7% as much as a conventional ventilator.

28 May 2020

Nanoscope received NIH grant to advance ultrafast laser-based gene delivery to the retina

The Nanoscope team has developed Multi-Characteristic Opsins to sensitize cells toward low level of white light so that vision is improved at ambient room light.

28 May 2020

Oncologists highlight the need for more palliative care training

Oncologists who practice and teach at the Johns Hopkins Kimmel Cancer Center are calling on medical oncology training programs to invest substantially more time educating physicians about palliative care and how to talk to patients about "bad news."

28 May 2020

Genomic variation and descent of SARS-CoV-2 strains in India

The pandemic of COVID-19 that is still affecting over 188 countries and territories the world over has taken over 359,000 lives in just under five months, while affecting at least 5.8 million people. Different strains have diverged from the original strain detected in Wuhan, China.

28 May 2020

Study reports COVID-19 case-fatality trends among people with IDD

A new study published recently in ScienceDirect by researchers from Syracuse University and SUNY Upstate Medical University shows that people with intellectual and developmental disabilities (IDD) are more likely to die from COVID-19 than those without IDD.

28 May 2020

Combination therapy found to be effective against IDH1-mutated acute myeloid leukemia

A combination therapy of ivosenidib (IVO) plus venetoclax (VEN) with or without azacitidine (AZA) was found to be effective against a specific genetic subtype of acute myeloid leukemia (AML) in a Phase Ib/II trial led by researchers at The University of Texas MD Anderson Cancer Center.

28 May 2020

Targeted drugs shrink breast cancer tumors in mice without toxic side effects

A team of researchers led by Worcester Polytechnic Institute Provost Wole Soboyejo has identified targeted drugs that reduced the sizes of hard-to-treat breast cancer tumors in mice without inducing the toxic side effects that are typically associated with conventional chemotherapy.

28 May 2020

Temple research suggests new way to prevent abdominal aortic aneurysm therapeutically

The main thoroughfare that carries oxygen-rich blood from the heart to the abdomen is known as the abdominal aorta.

28 May 2020

Study provides groundwork for restoring nerve-muscle connection in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles.

28 May 2020

Scientists from gnomAD Consortium release first set of discoveries on human genetic variation

For the last eight years, the Genome Aggregation Database Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more than 125,000 exomes and 15,000 whole genomes from populations around the world.

28 May 2020

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

A new study published on the online preprint server bioRxiv in May 2020 reports the construction and testing of a new ferritin-based antigen-bearing protein that has biological activity towards the ACE2 receptor. This could indicate its potential for development as a vaccine or antiviral.

28 May 2020

$Study finds increase in pediatric fractures sustained at home during COVID-19 pandemic$

Study finds increase in pediatric fractures sustained at home during COVID-19 pandemic

COVID-19 social distancing measures, including the closure of schools and parks and the indefinite cancellation of team sports, have led to a nearly 60% decrease overall in pediatric fractures but an increase in the proportion of fractures sustained at home, according to a new study by researchers at Children's Hospital of Philadelphia.

28 May 2020

Study finds gender differences in autism severity changes during early childhood

During early childhood, girls with autism tend to show greater reduction and less rise in their autism symptom severity than boys with autism, a UC Davis MIND Institute study has found.

28 May 2020

Research News and Research

How comorbidities affect SARS-CoV-2 viral entry

Face masks essential in combating asymptomatic spread of SARS-CoV-2 aerosols and droplets

Biophysicists reveal molecular mechanism behind light-driven sodium pumping

Stem cell treatments elicit full structural regeneration of the sun-aged skin

Research finds delayed treatment for ischemic stroke patients during COVID-19 pandemic

Ludwig Cancer Research study profiles immune landscape of brain tumors

Dual-pathway approach can lead to better outcomes in patients with heart stents

Brazilian researchers design low-cost mechanical ventilators

Nanoscope received NIH grant to advance ultrafast laser-based gene delivery to the retina

Oncologists highlight the need for more palliative care training

Genomic variation and descent of SARS-CoV-2 strains in India

Study reports COVID-19 case-fatality trends among people with IDD

Combination therapy found to be effective against IDH1-mutated acute myeloid leukemia

Targeted drugs shrink breast cancer tumors in mice without toxic side effects

Temple research suggests new way to prevent abdominal aortic aneurysm therapeutically

Study provides groundwork for restoring nerve-muscle connection in ALS

Scientists from gnomAD Consortium release first set of discoveries on human genetic variation

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

Study finds increase in pediatric fractures sustained at home during COVID-19 pandemic

Study finds gender differences in autism severity changes during early childhood

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