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Discovery of new biological pathway involved in pain processing offers hope for new treatments

The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at McGill University.

8 Aug 2017

Newly discovered biomarker linked to rare metabolic disorders may facilitate better diagnosis

A newly discovered biomarker associated with a rare metabolic disorder may facilitate better diagnosis and identification of new drugs for clinical trials for the disease, according to researchers in the Perelman School of Medicine at the University of Pennsylvania.

7 Aug 2017

New clinical trial examines potential role of drug combination therapy to eliminate LAM cells

Researchers at the University of Cincinnati begin a new clinical trial this fall, examining the potential role of a drug combination therapy to eliminate lymphangioleiomyomatosis (LAM) cells.

7 Aug 2017

Bioactive 'tissue papers' show potential for regenerative medicine

Northwestern Medicine scientists and engineers have invented a range of bioactive "tissue papers" made of materials derived from organs that are thin and flexible enough to even fold into an origami bird.

7 Aug 2017

Hitgen and LEO Pharma collaborate to discover small molecule leads for multiple therapeutic targets

HitGen Ltd announced that the company has entered into a multi-target multi-year collaboration with LEO Pharma A/S, to discover novel small molecule leads for multiple therapeutic targets of interest to LEO Pharma.

7 Aug 2017

New profiling procedure reveals role of immunoresolvents in blood coagulation

Stopping a wound from bleeding is essential for human health. Blood coagulation - in which blood goes from liquid to gel and forms a clot - can prevent excessive bleeding and infection. But exactly what molecular events transpire when blood coagulates has remained somewhat mysterious.

4 Aug 2017

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Omeros Corporation today announced that OMS721 has received orphan drug designation from the U.S. Food and Drug Administration for the treatment of Immunoglobulin A (IgA) nephropathy.

4 Aug 2017

Botulinum neurotoxin type X holds potential to open up new field of toxin therapeutics

Botulinum toxins are currently used on more than 80 medical conditions including Muscle spasms, Overactive bladder, Chronic migraine, Cervical dystonia, Sweating and Cerebral Palsy (CP).

3 Aug 2017

In-depth tumor sequencing reveals key molecular drivers of metastatic cancers

Five hundred cancer patients are getting an in-depth look at their genomes as part of a new clinical study that is revealing some of the key molecular drivers of metastatic cancers.

3 Aug 2017

SNMMI recognizes contributions to nuclear medicine and molecular imaging at 2017 annual meeting

The Society of Nuclear Medicine and Molecular Imaging (SNMMI), an international scientific and medical organization, recognized contributions to the field of nuclear medicine and molecular imaging during its 2017 Annual Meeting in Denver, Colorado. Several awards ceremonies were held to recognize the valuable role SNMMI members play in advancing the diagnosis and treatment of heart disease, cancer and neurological conditions.

2 Aug 2017

Takeda and Cardurion announce creation of new cardiovascular development partnership

Takeda Pharmaceutical Company Limited and Cardurion Pharmaceuticals today announced the creation of a new cardiovascular development partnership.

2 Aug 2017

U.S. FDA approves updated labeling for pan-genotypic single tablet regimen for HCV/HIV co-infected patients

Gilead Sciences, Inc. today announced that the U.S. Food and Drug Administration has approved updated labeling for Epclusa (sofosbuvir 400mg/velpatasvir 100mg), the first all-oral, pan-genotypic, once-daily single tablet regimen (STR) for the treatment of adults with chronic hepatitis C virus (HCV) infection, to include use in patients co-infected with HIV.

1 Aug 2017

Cell signaling molecules may be key to repairing diabetic nerve injury

Molecules that help cells communicate with each other--called cytokines--might be the key to repairing diabetic nerve damage, according to a new study published in Experimental Neurology. painful side effects.

1 Aug 2017

Bringing highly potent cell therapy products to market

There are two main challenges and both relate to manufacturing. The first one is to make sure you can manufacture therapies with reasonable costs and the second one is to make sure that you can balance the capacity you need with the demands.

31 Jul 2017

Juvenescence AI to develop first compounds generated by Insilico's deep-learned drug discovery engines

Insilico Medicine, a Baltimore-based leader in artificial intelligence for drug discovery and biomarker development, is pleased to announce a multi-year drug development agreement with the biotechnology company Juvenescence AI Limited.

28 Jul 2017

Synthetic molecule can disrupt hunger-signaling pathway, research suggests

New research suggests that a man-made cousin of a small molecule found in olive oil can disrupt the hunger-signaling pathway.

27 Jul 2017

Stem cell-based method selectively targets cancerous tissue while preventing toxic side effects

A stem cell-based method created by University of California, Irvine scientists can selectively target and kill cancerous tissue while preventing some of the toxic side effects of chemotherapy by treating the disease in a more localized way.

27 Jul 2017

Researchers discover potential chemical 'silver bullet' to reduce risk of colon cancer

In preclinical experiments, researchers at VCU Massey Cancer Center have uncovered a new way in which colon cancer develops, as well as a potential "silver bullet" for preventing and treating it.

26 Jul 2017

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

A new cooperative research study including Norris Cotton Cancer Center's Lionel Lewis, MB BCh, MD, finds that nivolumab plus ipilimumab therapy demonstrated manageable safety, notable antitumor activity, and durable responses with promising long term overall survival in patients with metastatic renal cell cancer (mRCC).

26 Jul 2017

MRI techniques can help spot, track cognitive impairment in professional fighters

Images of the brain's gray and white matter obtained with multiple MRI techniques can help identify and track cognitive impairment in active professional fighters, according to a new study published online in the journal Radiology.

25 Jul 2017

Therapeutics News and Research

Discovery of new biological pathway involved in pain processing offers hope for new treatments

Newly discovered biomarker linked to rare metabolic disorders may facilitate better diagnosis

New clinical trial examines potential role of drug combination therapy to eliminate LAM cells

Bioactive 'tissue papers' show potential for regenerative medicine

Hitgen and LEO Pharma collaborate to discover small molecule leads for multiple therapeutic targets

New profiling procedure reveals role of immunoresolvents in blood coagulation

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Botulinum neurotoxin type X holds potential to open up new field of toxin therapeutics

In-depth tumor sequencing reveals key molecular drivers of metastatic cancers

SNMMI recognizes contributions to nuclear medicine and molecular imaging at 2017 annual meeting

Takeda and Cardurion announce creation of new cardiovascular development partnership

U.S. FDA approves updated labeling for pan-genotypic single tablet regimen for HCV/HIV co-infected patients

Cell signaling molecules may be key to repairing diabetic nerve injury

Bringing highly potent cell therapy products to market

Juvenescence AI to develop first compounds generated by Insilico's deep-learned drug discovery engines

Synthetic molecule can disrupt hunger-signaling pathway, research suggests

Stem cell-based method selectively targets cancerous tissue while preventing toxic side effects

Researchers discover potential chemical 'silver bullet' to reduce risk of colon cancer

Combination therapy shows efficacy, safety in treating metastatic renal cell cancer

MRI techniques can help spot, track cognitive impairment in professional fighters

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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