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New method could increase number of genetic components in synthetic biologists' toolkit

Through the assembly of genetic components into "circuits" that perform logical operations in living cells, synthetic biologists aim to artificially empower cells to solve critical problems in medicine, energy and the environment. To succeed, however, they'll need far more reliable genetic components than the small number of "off-the-shelf" bacterial parts now available.

3 Aug 2012

Iced tea can lead to formation of kidney stones

This is the peak season for drinking iced tea, but a Loyola University Medical Center urologist is warning the popular drink can contribute to painful kidney stones.

3 Aug 2012

Researchers develop robotic companion and intelligent home environment for elderly people

A team of EU-funded researchers has developed a robotic companion and intelligent home environment that could help elderly people live richer and more independent lives and reduce the burden placed on healthcare services.

3 Aug 2012

Weill Cornell Medical College receives NCATS grant to fund Clinical and Translational Science Center

Weill Cornell Medical College has received $49.6 million from the National Center for Advancing Translational Sciences (NCATS), of the National Institutes of Health (NIH), to fund its Clinical and Translational Science Center (CTSC).

3 Aug 2012

Access to dental care alone is not sufficient to meet oral health needs of adults with I/DD

A comprehensive study using electronic dental records to profile the oral health status of adults with intellectual and developmental disabilities (I/DD) has concluded that access to specialized dental care alone is not sufficient to meet the community's substantial oral health needs.

2 Aug 2012

IHME study identifies discrepancies between national surveys that track obesity

Despite the increasing awareness of the problem of obesity in the United States, most Americans don't know whether they are gaining or losing weight, according to new research from the Institute for Health Metrics and Evaluation at the University of Washington.

2 Aug 2012

BMC to implement and evaluate opioid risk reduction model in primary care settings

Researchers at Boston Medical Center (BMC) have received a $2.67 million grant from the National Institute on Drug Abuse (NIDA) to implement and evaluate a new model of care in primary care settings aimed at decreasing the misuse of and addiction to opioids among patients with chronic pain.

2 Aug 2012

FDA clearance - scoliosis - DePuy synthes spine

DePuy Synthes Spine announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for use of its EXPEDIUM®, VIPER®, and VIPER®2 Spine Systems on patients with adolescent idiopathic scoliosis (AIS), an abnormal curvature of the spine that typically affects children between the ages of 10 and 18.(1) This expands the scoliosis indication for the pedicle screw systems, which now are indicated for both adolescents and adults.

2 Aug 2012

Internet infant sleep safety information may be suspect

Only around 60% of websites provide information on infant sleep safety that is consistent with the American Academy of Pediatrics official recommendations, report US researchers.

2 Aug 2012

Increased cortical thinning in schizophrenia patients

Patients with schizophrenia show greater cortical thinning in selected subregions of both the frontal and temporal lobes over a 2-year period than mentally healthy individuals, study results show.

2 Aug 2012

Train-Match-Fit-Streamline uses 11 factors to quickly pair likely drugs and diseases

With the cost of putting a single new drug on the pharmacy shelves topping a staggering $1 billion, scientists are reporting development of a way to determine if an already-approved drug might be used to treat a different disease. The technique for repurposing existing medicines could cut drug development costs and make new medicine available to patients faster, they report in ACS' Journal of Medicinal Chemistry.

2 Aug 2012

Investigational drug shows promise against most severe form of congenital hyperinsulinism

A pilot study in adolescents and adults has found that an investigational drug shows promise as the first potential medical treatment for children with the severest type of congenital hyperinsulinism, a rare but potentially devastating disease in which gene mutations cause insulin levels to become dangerously high.

2 Aug 2012

Researchers report one-third cut in the rate of lethal SSIs after colorectal operations

A patient safety team including researchers in the Johns Hopkins Armstrong Institute for Patient Safety and Quality reported a one-third cut in the rate of costly and potentially lethal surgical site infections (SSIs) following colorectal operations after requiring use of a simple safety checklist and urging caregivers to speak up if they see potentially unsafe practices.

2 Aug 2012

MDCH unveils Michigan’s Infant Mortality Reduction Plan

The Michigan Department of Community Health (MDCH) has unveiled the state's Infant Mortality Reduction Plan, a strategy that includes significant recommendations developed from medical research conducted by the Perinatology Research Branch (PRB) of the Eunice Kennedy Shriver National Institute for Child Health and Human Development, National Institutes of Health (NICHD/NIH), at the Wayne State University School of Medicine.

2 Aug 2012

Combination hormonal therapy improves survival in advanced breast cancer

A study co-authored by a Loyola researcher and published in the New England Journal of Medicine is offering new hope to women with advanced breast cancer.

2 Aug 2012

Internet searches related to infant sleep safety often do not reflect AAP recommendations

In 2010, 59% of the U.S. population used internet searches for health information, and parents searching for information regarding their children were among the top users. In 2011, the American Academy of Pediatrics (AAP) published recommendations for infant sleep safety to reduce the risk of sudden infant death syndrome (SIDS), suffocation, strangulation, and other accidental sleep-related deaths.

2 Aug 2012

Combination of anastrozole and fulvestrant extends survival in women with metastatic breast cancer

Results of a SWOG clinical trial published August 2 in the New England Journal of Medicine show the combination of anastrozole and fulvestrant extended the median survival time of women with hormone receptor-positive metastatic breast cancer by more than six months compared to women treated with a standard therapy of anastrozole alone (47.7 months vs 41.3 months).

2 Aug 2012

B-cell substances may play a role in MS progression

Wayne State University School of Medicine researchers, working with colleagues in Canada, have found that one or more substances produced by a type of immune cell in people with multiple sclerosis (MS) may play a role in the disease's progression. The finding could lead to new targeted therapies for MS treatment.

2 Aug 2012

New FDA risk management plan aims to reduce opioid abuse in the U.S.

A new risk management plan from the U.S. Food and Drug Administration to help clinicians properly prescribe drugs with addiction potential aims to help reduce the growing epidemic of opioid abuse in the United States.

2 Aug 2012

Three papers focus on nucleosomes and may help uncover the rules governing gene transcription

A trio of groundbreaking publications from researchers in Northwestern University's Physical Sciences-Oncology Center (PS-OC) report important methodological advances that will enable a better understanding of how gene expression is regulated, both in normal cells and in cancer cells. This knowledge could lead to the development of more effective therapeutic agents to treat cancer patients.

2 Aug 2012

Medicine News and Research

New method could increase number of genetic components in synthetic biologists' toolkit

Iced tea can lead to formation of kidney stones

Researchers develop robotic companion and intelligent home environment for elderly people

Weill Cornell Medical College receives NCATS grant to fund Clinical and Translational Science Center

Access to dental care alone is not sufficient to meet oral health needs of adults with I/DD

IHME study identifies discrepancies between national surveys that track obesity

BMC to implement and evaluate opioid risk reduction model in primary care settings

FDA clearance - scoliosis - DePuy synthes spine

Internet infant sleep safety information may be suspect

Increased cortical thinning in schizophrenia patients

Train-Match-Fit-Streamline uses 11 factors to quickly pair likely drugs and diseases

Investigational drug shows promise against most severe form of congenital hyperinsulinism

Researchers report one-third cut in the rate of lethal SSIs after colorectal operations

MDCH unveils Michigan’s Infant Mortality Reduction Plan

Combination hormonal therapy improves survival in advanced breast cancer

Internet searches related to infant sleep safety often do not reflect AAP recommendations

Combination of anastrozole and fulvestrant extends survival in women with metastatic breast cancer

B-cell substances may play a role in MS progression

New FDA risk management plan aims to reduce opioid abuse in the U.S.

Three papers focus on nucleosomes and may help uncover the rules governing gene transcription

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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