Antibodies News and Research

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Steroids and immunotherapy improve outcomes in children with COVID-related multi-system inflammatory syndrome

Treatment with antibodies purified from donated blood - immune globulin therapy - and steroids restored heart function in the majority of children with COVID-related multi-system inflammatory syndrome, according to new research published yesterday in Circulation, the flagship journal of the American Heart Association.

19 May 2020

X-ray experiments demonstrate a new way to block the entry of SARS-CoV-2

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

19 May 2020

New capsules are critical for addressing the rapidly changing bacteria, says expert

Vaccines that protect people from infection by Streptococcus pneumonia, which kills up to 1 million children every year worldwide, train the immune system to recognize the pathogen's thick sugar capsule.

19 May 2020

‘Last responders’ seek to expand postmortem COVID testing in unexplained deaths

Examining dead bodies and probing for a cause of death is rarely seen as a heroic or glamorous job. Rather, as the coronavirus pandemic has unfolded, all eyes have been on the medical workers and public health disease detectives fighting on the front lines - and sometimes giving their lives — to bring the novel coronavirus under control.

19 May 2020

Fewer traffic collisions during shutdown means longer waits for organ donations

On Day Two of the San Francisco Bay Area's stay-at-home orders in March, Nohemi Jimenez got into her car in San Pablo, California, waved goodbye to her 3-year-old son and drove to her regular Wednesday dialysis appointment.

19 May 2020

Gene variants can increase risk of schizophrenia, shows study

Variants in a gene of the human immune system cause men and women to have different vulnerabilities to the autoimmune diseases lupus and Sjögren's syndrome, according to findings published in the journal Nature.

19 May 2020

Study: Certain inflammatory demyelinating diseases belong to different category than multiple sclerosis

An antibody appears to make a big difference between multiple sclerosis and other disorders affecting the protective myelin sheath around nerve fibers, report Tohoku University scientists and colleagues in the journal Brain.

19 May 2020

Oxford Immunotec releases the T-SPOT® Discovery™ SARS-CoV-2 kit

Oxford Immunotec Global PLC, a global, high-growth diagnostics company, today announces the release of the T-SPOT Discovery SARS-CoV-2 test kit.

19 May 2020

New vaccine appears to be highly protective against Ebola infection in mice

As the world focuses on finding a COVID-19 vaccine, research continues on other potentially catastrophic pandemic diseases, including Ebola and Marburg viruses.

18 May 2020

Human immune repertoire may not commonly produce cross-neutralizing antibodies to coronaviruses

Patients infected with either severe acute respiratory syndrome coronavirus (SARS-CoV) or SARS-CoV-2 produce antibodies that bind to the other coronavirus, but the cross-reactive antibodies are not cross protective, at least in cell-culture experiments, researchers report May 17 in the journal Cell Reports.

18 May 2020

Scant clinical research for pregnant and lactating women with COVID-19

Pregnant and breastfeeding women have been excluded from clinical trials of drugs to treat COVID-19, and as result, there is no safety data to inform clinical decisions. Such drugs include remdesivir according to a new article in the peer-reviewed journal Breastfeeding Medicine.

18 May 2020

SMART researchers awarded NMRC funding to develop rapid paper-based COVID-19 tests

Singapore-MIT Alliance for Research and Technology, MIT's research enterprise in Singapore, has received a grant from the National Medical Research Council COVID-19 Research fund for the acceleration of research and development of rapid paper-based serological and diagnostic tests for COVID-19.

18 May 2020

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

A research group from Harvard Medical School reported two cryo-electron microscopy structures derived from a single preparation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein in their paper available on the preprint server bioRxiv. Understanding the nuances of prefusion and postfusion conformations shed light on viral cell entry and may, in turn, guide the development of vaccines and drugs.

18 May 2020

Cross-neutralization of SARS and COVID-19 coronaviruses by a monoclonal antibody

An antibody first identified in a blood sample from a patient who recovered from Severe Acute Respiratory Syndrome in 2003 inhibits related coronaviruses, including the cause of COVID-19.

18 May 2020

University of Valencia files patent application for COVID-19 vaccine

The University of Valencia has filed a patent application for a vaccine candidate against COVID-19, developed by a research team from the Department of Microbiology

18 May 2020

Avacta's SARS-COV-2 neutralizing Affimer reagents show therapeutic potential for COVID-19

Avacta Group plc, the developer of Affimer biotherapeutics and reagents, is pleased to announce that several of the Affimer reagents recently generated for development of a point-of-care COVID-19 antigen saliva test have now also been shown to block the interaction between the virus’ spike protein and ACE2, a receptor on human cells that is key to the virus infection pathway.

From Avacta Life Sciences Ltd. 18 May 2020

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

Boehringer Ingelheim today announced the acquisition of Northern Biologics Inc., a wholly owned subsidiary of Northern LP. By acquiring this entity, which focuses on therapeutic antibodies targeting the tumor microenvironment, Boehringer Ingelheim is now positioned at the forefront of the stromal biology space - an emerging area in cancer immunology.

From Boehringer Ingelheim International GmbH 18 May 2020

Oxford University vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

As the world continues to grapple with the coronavirus pandemic, many scientists, institutions, and pharmaceutical companies are working hard to develop an effective vaccine.

18 May 2020

Kawasaki disease outbreak in children with COVID-19

The ongoing COVID-19 pandemic has marched its way to almost all parts of the world, with hundreds of thousands of deaths and over 4.5 million cases as of May 15, 2020. One saving grace has been the apparent sparing of children, though the mortality in older people is quite high.

17 May 2020

New and unexplored angle in the binding of SARS-CoV-2 to host cells

Researchers in the Netherlands, Cuba, and Italy have made important discoveries about the carbohydrate-mediated binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to host cell lectin receptors and host lung microbiota.

17 May 2020

Antibodies News and Research

Steroids and immunotherapy improve outcomes in children with COVID-related multi-system inflammatory syndrome

X-ray experiments demonstrate a new way to block the entry of SARS-CoV-2

New capsules are critical for addressing the rapidly changing bacteria, says expert

‘Last responders’ seek to expand postmortem COVID testing in unexplained deaths

Fewer traffic collisions during shutdown means longer waits for organ donations

Gene variants can increase risk of schizophrenia, shows study

Study: Certain inflammatory demyelinating diseases belong to different category than multiple sclerosis

Oxford Immunotec releases the T-SPOT® Discovery™ SARS-CoV-2 kit

New vaccine appears to be highly protective against Ebola infection in mice

Human immune repertoire may not commonly produce cross-neutralizing antibodies to coronaviruses

Scant clinical research for pregnant and lactating women with COVID-19

SMART researchers awarded NMRC funding to develop rapid paper-based COVID-19 tests

Novel insights on SARS-CoV-2 cell entry may inform further vaccine and treatment development

Cross-neutralization of SARS and COVID-19 coronaviruses by a monoclonal antibody

University of Valencia files patent application for COVID-19 vaccine

Avacta's SARS-COV-2 neutralizing Affimer reagents show therapeutic potential for COVID-19

Boehringer Ingelheim acquires Northern Biologics to expand cancer immunology portfolio

Oxford University vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

Kawasaki disease outbreak in children with COVID-19

New and unexplored angle in the binding of SARS-CoV-2 to host cells

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