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Lipidomics and metabolomics as potential biomarkers for breast cancer progression

This review highlights the potential of lipidomic and metabolomic biomarkers in predicting breast cancer prognosis and therapy response, enhancing patient care.

5 Sep 2024

A new genetic perspective on monilethrix

From infancy and usually for life, some families suffer from broken hair due to a congenital form of hair loss called monilethrix. Researchers at the University Hospital Bonn and the University of Bonn have now identified causative mutations in another keratin gene, KRT31. They hope that this will improve the diagnosis of this rare disease. Their results have now been published in the renowned "British Journal of Dermatology".

5 Sep 2024

New insights into stiff-person syndrome, advancing diagnosis and treatment

Research explores the complexities of diagnosing and treating stiff-person syndrome, emphasizing the uncertain role of GAD antibodies and the promise of novel therapies.

5 Sep 2024

Scientists advance type 1 diabetes treatment with cutting-edge stem cell and gene editing technologies

Researchers review significant advancements and ongoing challenges in cell replacement therapies for type 1 diabetes, highlighting innovative approaches in stem cell-derived islets and immune protection strategies.

5 Sep 2024

Promising new strategy to combat fungal infections

A group of Brazilian researchers has found a potential target for novel therapeutic strategies to combat fungal infections – more specifically, those caused by Aspergillus fumigatus. An article reporting the discovery is published in the journal Communications Biology.

5 Sep 2024

Understanding the hormonal paradox in prostate cancer progression

A treatment paradox has recently come to light in prostate cancer: Blocking testosterone production halts tumor growth in early disease, while elevating the hormone can delay disease progression in patients whose disease has advanced.

4 Sep 2024

Astrocytes reprogrammed to brain stem cells through methylation

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain.

4 Sep 2024

Study explores the effects of hyperosmotic stress on microglial cells

Microglia are the brain's immune cells known to play a vital role in maintaining neural function and responding to potential threats.

4 Sep 2024

Study uncovers key enzyme link between obesity and atrial fibrillation

A cellular link between obesity and atrial fibrillation - a heart condition that afflicts over 33 million people worldwide - presents a promising target for new therapies, researchers from the University of Illinois Chicago report.

4 Sep 2024

Magnetic nanoparticles enhance safe thawing of cryopreserved tissues

Every day, people die waiting for an organ transplant. Time is at a premium, not just for those awaiting organs, but also for the organs themselves, which can deteriorate rapidly during transportation.

4 Sep 2024

Allen Institute and NYSCF launch collaboration to create inclusive cellular models

Today, the Allen Institute for Cell Science and New York Stem Cell Foundation (NYSCF) announced a pioneering collaboration to address this critical issue, combining two cutting-edge technologies to create more inclusive cellular models for studying disease.

4 Sep 2024

New immunotherapy approach shows promise for minimizing spinal cord injury damage

WashU Medicine researchers have designed, in mice, an approach to minimizing the damage from a spinal cord injury through the use of engineered immune cells.

4 Sep 2024

Evaluating underwater endoscopic mucosal resection for gastrointestinal neuroendocrine tumors

Neuroendocrine tumors (NETs) of the gastrointestinal (GI) tract are a rare and heterogeneous group of malignancies arising from the neuroendocrine cell system.

4 Sep 2024

Understanding the impact of BMI on colorectal cancer risk in Asia

Researchers report that body mass index values in Asians population may predict the risk of developing colorectal cancer.

4 Sep 2024

Scientists uncover shared gene expression patterns in aging and psychiatric disorders

Researchers reveal how aging and psychiatric disorders converge at the cellular level in the orbitofrontal cortex, identifying key gene expression changes that could lead to new therapies.

4 Sep 2024

Study reassures patients about semaglutide safety

Taking the weight loss medication semaglutide did not increase the risk of depressive symptoms, suicidal thoughts, or suicidal behavior in persons without known major mental health disorders, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania published this week in JAMA Internal Medicine.

4 Sep 2024

CDK4/6 inhibitors show promise for pediatric high-grade glioma treatment

CDK4/6 inhibitors, which are already FDA approved for the treatment of other forms of cancer, show early signs of promise in the treatment of a subtype of pediatric high-grade glioma, according to new research from Dana-Farber Cancer Institute and the Institute of Cancer Research in London.

3 Sep 2024

Discovery of cellular process could impact the understanding of cancer and aging

Researchers at UC Merced used fruit flies to uncover a cellular process common to many organisms that could dramatically impact the understanding of cancer and aging.

3 Sep 2024

PQBP3 protein found to play key role in aging and brain disorders

In a recent study published online on August 5 2024 in The EMBO Journal, researchers from Tokyo Medical and Dental University (TMDU) in Japan have uncovered a crucial piece of this puzzle by focusing on the role of a single nucleolar protein.

3 Sep 2024

Delayed antiviral treatment still beneficial for immunocompromised COVID-19 patients

Starting antiviral treatment as late as 14 days after infection with SARS-CoV-2 may still be beneficial in hosts with compromised immune systems, who are at greatest risk of developing severe COVID-19, according to researchers in the Center for Translational Antiviral Research at Georgia State University's Institute for Biomedical Sciences.

3 Sep 2024

Cell News and Research

Lipidomics and metabolomics as potential biomarkers for breast cancer progression

A new genetic perspective on monilethrix

New insights into stiff-person syndrome, advancing diagnosis and treatment

Scientists advance type 1 diabetes treatment with cutting-edge stem cell and gene editing technologies

Promising new strategy to combat fungal infections

Understanding the hormonal paradox in prostate cancer progression

Astrocytes reprogrammed to brain stem cells through methylation

Study explores the effects of hyperosmotic stress on microglial cells

Study uncovers key enzyme link between obesity and atrial fibrillation

Magnetic nanoparticles enhance safe thawing of cryopreserved tissues

Allen Institute and NYSCF launch collaboration to create inclusive cellular models

New immunotherapy approach shows promise for minimizing spinal cord injury damage

Evaluating underwater endoscopic mucosal resection for gastrointestinal neuroendocrine tumors

Understanding the impact of BMI on colorectal cancer risk in Asia

Scientists uncover shared gene expression patterns in aging and psychiatric disorders

Study reassures patients about semaglutide safety

CDK4/6 inhibitors show promise for pediatric high-grade glioma treatment

Discovery of cellular process could impact the understanding of cancer and aging

PQBP3 protein found to play key role in aging and brain disorders

Delayed antiviral treatment still beneficial for immunocompromised COVID-19 patients

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo