Clinical Trial News and Research

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Scientists target metastasis in the battle against cancer

An experimental combination drug therapy attacking the DNA integrity of cancer cells is showing promise for a possible new cancer therapy in the future.

29 Mar 2019

Cancer prevention drug also reduces virulence of H. pylori bacterium

A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.

29 Mar 2019

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

Researchers at Dana-Farber/Boston Children's Cancer and Blood Disorders Center and the University of Massachusetts Medical School have developed a strategy to treat two of the most common inherited blood diseases -- sickle cell disease and beta thalassemia -- applying CRISPR-Cas9 gene editing to patients' own blood stem cells.

29 Mar 2019

FDA approves treatment for adults with non-radiographic axial spondyloarthritis

The U.S. Food and Drug Administration today approved Cimzia (certolizumab pegol) injection for treatment of adults with a certain type of inflammatory arthritis called non-radiographic axial spondyloarthritis (nr-axSpA), with objective signs of inflammation. This is the first time that the FDA has approved a treatment for nr-axSpA.

28 Mar 2019

Lab-grown blood vessels provide hope for dialysis patients

Research published this week describes how lab-grown blood vessels were transformed into living tissue when grafted into dialysis patients needing replacement blood vessels.

28 Mar 2019

European Research Council awards grant for research on insulin-producing cells

The ERC Advanced Grant is one of the most prestigious funding programmes for research in Europe. Per-Olof Berggren, professor of experimental endocrinology at Karolinska Institutet, is now awarded this grant for the second time.

28 Mar 2019

First-of-its-kind smartphone app predicts dietary lapses

More than two-thirds of adults in the United States are overweight and half of them are trying to lose weight, according to the Centers for Disease Control and Prevention.

28 Mar 2019

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

A pioneering clinical trial investigating medicinal cannabis as a potential treatment for people living with severe Tourette syndrome will be conducted by Wesley Medical Research, in Brisbane in Australia, with cannabis supply facilitated by Lambert Initiative for Cannabinoid Therapeutics at University of Sydney.

28 Mar 2019

FDA approves new oral treatment for men with certain forms of hypogonadism

The U.S. Food and Drug Administration today approved Jatenzo (testosterone undecanoate), an oral testosterone capsule to treat men with certain forms of hypogonadism.

27 Mar 2019

Male contraceptive pill crosses the human clinical trial hurdle

Birth control pills have been around for the past six decades but have been for use of women only. A team of researchers this week have announced the success of the first male birth control pill that could safely prevent pregnancy.

27 Mar 2019

FDA approves new drug to treat adults with relapsing forms of MS

The U.S. Food and Drug Administration today approved Mayzent (siponimod) tablets to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease.

27 Mar 2019

LNC Therapeutics announces grant of Cornell University patent relating to christensenella bacteria

LNC Therapeutics, a French biotech company specializing in gut microbiome-based drug discovery, announced today the grant of the Cornell University (Ithaca, New-York, USA) patent relating to christensenella bacteria.

26 Mar 2019

New self-guided treatment using smartphone and VR viewer effective in reducing fear of heights

A fully self-guided treatment using virtual reality is effective in reducing fear of heights. A team of researchers from Vrije Universiteit Amsterdam and the University of Twente, led by Dr. Tara Donker, developed ZeroPhobia (www.zerophobia.app), a treatment delivered through a smartphone app and a basic VR viewer.

26 Mar 2019

Inherited form of rickets improves more with new injectable medicine than conventional therapy

Burosumab, a new injectable medicine to treat X-linked hypophosphatemia (XLH), an inherited form of rickets, demonstrates superior improvements in rickets and other outcomes compared with conventional therapy in an international, phase 3 clinical trial in children.

25 Mar 2019

Older adults with type 1 diabetes have hypoglycemia over an hour a day

Older adults with type 1 diabetes typically have low blood sugar, or hypoglycemia, for more than an hour a day, suggests research to be presented Monday, March 25 at ENDO 2019, the annual meeting of the Endocrine Society, in New Orleans, La.

25 Mar 2019

Shaping new treatments for tuberculosis

To commemorate World TB Day, a Special Collection has been released by PLOS Medicine containing a series of articles that articulate the essential new steps in clinical research that will pave the way for the development of tomorrow's optimal treatment for all forms of tuberculosis.

25 Mar 2019

Financial incentives fail to increase completion rates of colorectal cancer screening tests mailed to patients

Financial incentives didn't increase completion rates of colorectal cancer screening tests mailed to patients.

25 Mar 2019

NIH starts clinical trial of drug to treat cravings associated with opioid use disorder

A clinical trial of an experimental drug designed to treat cravings associated with opioid use disorder has begun in the National Institutes of Health Clinical Center.

22 Mar 2019

Pitt engineers win $550,000 NSF CAREER award to develop new intervention for people with ASD

Autism was first described by U.S. researchers more than 70 years ago, and today the Centers for Disease Control and Prevention estimates that 1 in 59 children are identified with autism spectrum disorder, affecting more than 3.5 million Americans.

22 Mar 2019

City of Hope exhibits current studies and data on cancer therapies at AACR

City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, will showcase ongoing studies and data on chimeric antigen receptor T cell therapy, immunotherapy against solid tumors and more at the American Association for Cancer Research annual meeting from March 29 through April 3 in Atlanta.

22 Mar 2019

Clinical Trial News and Research

Scientists target metastasis in the battle against cancer

Cancer prevention drug also reduces virulence of H. pylori bacterium

Researchers develop new strategy to treat sickle cell disease and beta thalassemia

FDA approves treatment for adults with non-radiographic axial spondyloarthritis

Lab-grown blood vessels provide hope for dialysis patients

European Research Council awards grant for research on insulin-producing cells

First-of-its-kind smartphone app predicts dietary lapses

Clinical trial examines medicinal cannabis as potential treatment for severe Tourette syndrome

FDA approves new oral treatment for men with certain forms of hypogonadism

Male contraceptive pill crosses the human clinical trial hurdle

FDA approves new drug to treat adults with relapsing forms of MS

LNC Therapeutics announces grant of Cornell University patent relating to christensenella bacteria

New self-guided treatment using smartphone and VR viewer effective in reducing fear of heights

Inherited form of rickets improves more with new injectable medicine than conventional therapy

Older adults with type 1 diabetes have hypoglycemia over an hour a day

Shaping new treatments for tuberculosis

Financial incentives fail to increase completion rates of colorectal cancer screening tests mailed to patients

NIH starts clinical trial of drug to treat cravings associated with opioid use disorder

Pitt engineers win $550,000 NSF CAREER award to develop new intervention for people with ASD

City of Hope exhibits current studies and data on cancer therapies at AACR

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