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Preemies treated with caffeine have better lung function in mid-childhood, study finds

Premature babies treated with caffeine have better lung function in mid-childhood than preemies not treated with caffeine, according to a randomized controlled trial published in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

14 Jul 2017

FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

A Food and Drug Administration (FDA) panel created history by recommending a gene therapy for patients with cancer. In this therapy the patient’s own genes would be modified to fight the cancer cells. The patient’s cells which are thus altered to treat the cancer would thus be termed as “living drugs” as they act as soldiers to treat the cancer. These cells boost up the immune system and help the body fight the cancer.

14 Jul 2017

Cellular antennae play key role in muscle-to-fat transformation

Like it or not, as we age, our muscle cells are slowly exchanged, one by one, for fat cells. This process quickens when we injure a muscle, and an extreme form of this process is also seen in muscle-wasting diseases such as Duchenne muscular dystrophy (DMD).

13 Jul 2017

Aflatoxin detection in milk research, the SYMPHONY project, is completed

On 11 July 2017, Epigem celebrated the completion of its research into Aflatoxin detection in milk, as part of the EU-funded SYMPHONY project. At the same time, the company announced that it has filed a patent based on this work.

From Epigem Ltd. 13 Jul 2017

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia.

13 Jul 2017

E-Scape Bio announces extension of funding to develop novel drug for Alzheimer's disease

E-Scape Bio announced an extension of its Series A funding to a total of $63 million. Created as a spin-off from research conducted at the Gladstone Institutes, E-Scape Bio is a biopharmaceutical company with a mission to develop new therapies to treat neurodegenerative disorders such as Alzheimer's disease.

12 Jul 2017

Diabetes-induced changes in oral microbiome promote periodontal bone loss

A new study led by University of Pennsylvania researchers has found that the oral microbiome is affected by diabetes, causing a shift to increase its pathogenicity.

12 Jul 2017

Targeting acid metabolite reduces size and spread of breast cancer

It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability to spread to the lungs.

12 Jul 2017

UIC researchers identify enzyme that triggers corneal inflammation

One of the symptoms of herpes simplex virus-1 infection of the eye is lingering inflammation of the cornea – the clear outer layer of the eyeball.

11 Jul 2017

Synthetic compound that reads mitochondrial DNA could lead to treatments for nerve, muscle diseases

For the first time, a synthetic compound has been made that can bind to DNA in the cells' energy powerhouses, suppressing a gene associated with nerve and muscle disease.

11 Jul 2017

Collagen found to regulate epidermal proliferation in juvenile and aged skin

Type XVII collagen (COL17) is found to regulate the proliferation of epidermal cells and therefore the thickness of juvenile and aged skin, suggesting COL17 can potentially be used for future anti-aging strategies.

11 Jul 2017

Brazilian researchers reveal nanoparticle-based strategy to combat antibiotic-resistant bacteria

A new strategy to combat antibiotic-resistant bacteria has been described by Brazilian researchers in Scientific Reports, an online journal owned by Springer Nature.

11 Jul 2017

New technology could help patients requiring stem cell therapies for Parkinson's, stroke, other diseases

A groundbreaking advancement in materials from Northwestern University could potentially help patients requiring stem cell therapies for spinal cord injuries, stroke, Parkinson's disease, Alzheimer's disease, arthritic joints or any other condition requiring tissue regeneration, according to a new study.

10 Jul 2017

Clinical management of patients with Cancer of Unknown Primary using new epigenetic test

The invention of the EPICUP epigenetic test last year allowed physicians to elucidate what type of primary tumor had metastasized in patients with Cancer of Unknown Primary (CUP).

10 Jul 2017

UT Southwestern researchers develop novel chemical reaction that could accelerate drug development

Chemists have long sought to develop new reactions for the direct conversion of simple hydrocarbon building blocks into valuable materials such as pharmaceuticals in a way that dependably creates the same chemical bonds and orientations.

7 Jul 2017

Nanolock-nanopore detects cancer driver mutations to facilitate early diagnosis, treatment

The moment when healthy cells turn into cancer cells is a critical point. And if caught early enough, many cancers can be stopped in their tracks.

7 Jul 2017

Novel small molecule tracer for PET imaging spots blood clots

Blood clots in veins and arteries can lead to heart attack, stroke, and pulmonary embolism, which are major causes of mortality.

6 Jul 2017

New single probe method provides PCR-free detection of microRNA linked to liver toxicity

Quanterix Corporation, a company digitizing biomarker analysis with the goal of advancing the science of precision health, and DestiNA Genomics Ltd, a manufacturer of patented reagents for nucleic acid detection, today announced that PLOS ONE has published a proof-of-concept single probe method for detecting microRNA biomarkers associated with liver toxicity.

6 Jul 2017

IRB Barcelona scientists reveal role of Dpp gene in wing growth of fruit flies

Researchers working in the Development and Growth Control Lab at IRB Barcelona reveal that the Dpp gene (BMP in humans) plays a double role in the structural organization and growth of the wings of the fruit fly Drosophila melanogaster.

5 Jul 2017

Discovery could impact understanding, treatment of autoimmune and inflammatory diseases

Scientists from the Research Institute of the McGill University Health Centre may have cracked the code to understanding the function of special cells called regulatory T Cells.

5 Jul 2017

Molecule News and Research

Preemies treated with caffeine have better lung function in mid-childhood, study finds

FDA panel recommends new breakthrough gene therapy for B-cell acute lymphoblastic leukemia (ALL)

Cellular antennae play key role in muscle-to-fat transformation

Aflatoxin detection in milk research, the SYMPHONY project, is completed

Cord-blood-derived natural killer cells can be modified to destroy B-cell cancers

E-Scape Bio announces extension of funding to develop novel drug for Alzheimer's disease

Diabetes-induced changes in oral microbiome promote periodontal bone loss

Targeting acid metabolite reduces size and spread of breast cancer

UIC researchers identify enzyme that triggers corneal inflammation

Synthetic compound that reads mitochondrial DNA could lead to treatments for nerve, muscle diseases

Collagen found to regulate epidermal proliferation in juvenile and aged skin

Brazilian researchers reveal nanoparticle-based strategy to combat antibiotic-resistant bacteria

New technology could help patients requiring stem cell therapies for Parkinson's, stroke, other diseases

Clinical management of patients with Cancer of Unknown Primary using new epigenetic test

UT Southwestern researchers develop novel chemical reaction that could accelerate drug development

Nanolock-nanopore detects cancer driver mutations to facilitate early diagnosis, treatment

Novel small molecule tracer for PET imaging spots blood clots

New single probe method provides PCR-free detection of microRNA linked to liver toxicity

IRB Barcelona scientists reveal role of Dpp gene in wing growth of fruit flies

Discovery could impact understanding, treatment of autoimmune and inflammatory diseases

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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