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New discovery about microglia heralds myriad possibilities for treating neurodegenerative diseases

Combating Alzheimer's and other neurodegenerative diseases by inserting healthy new immune cells into the brain has taken a leap toward reality.

30 Jan 2023

Researchers discover mechanism underlying the development and intensification of cancer treatment-related pain

A combination of chemotherapy and drugs that stimulate the immune system to combat cancer is increasingly used to control progression of the disease in patients.

30 Jan 2023

New EV platform could help streamline the development and delivery of vaccines worldwide

To many, EV stands for "electric vehicle." To researchers at Harvard University and the University of Nebraska–Lincoln, it's shorthand for another vehicle - this one nanoscopic - that might help streamline the development and delivery of vaccines worldwide.

30 Jan 2023

New candidate molecule could become an effective non-hormonal male contraceptive

Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize an egg, yet these may not work for everyone.

30 Jan 2023

Novel class of sulfonamides to block malaria transmission

Malaria is a devastating disease, with 247 million cases and 619,000 deaths reported in 2021 alone. Malaria causes fever and a flu-like illness that occurs when people are infected with the parasite Plasmodium falciparum, which is spread by mosquitoes.

30 Jan 2023

Direct stochastic optical reconstruction microscopy combined with different labeling approaches for the visualization and quantification of ACE2 on different cells

Researchers performed dSTORM (direct stochastic optical reconstruction microscopy) with several labeling techniques for visualizing and quantifying ACE2 receptor expression on various cells.

30 Jan 2023

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Researchers investigated whether endothelial TLR3 insufficiency contributes to lung vascular remodeling induced by SARS-CoV-2.

30 Jan 2023

Does a second monovalent SARS-CoV-2 mRNA booster increase neutralizing activity to Omicron variants in nursing home residents and healthcare workers?

Researchers investigated whether the second booster dose of monovalent COVID-19 mRNA vaccines increases antibody titers and neutralization potential against the SARS-CoV-2 Omicron VOC among NH residents and HCWs.

30 Jan 2023

A baby spent 36 days in an in-network NICU. Why did the hospital next door send a bill?

Brenna Kearney was seven months pregnant in December 2019 when she experienced what she thought were bad flu symptoms.

30 Jan 2023

Study suggests robust lung mucosal immunity against SARS-CoV-2 can be better achieved through hybrid immunity, as opposed to peripheral vaccination alone

Researchers characterized immunological responses by pulmonary mucosal tissues post-COVID-19 vaccination and/or SARS-CoV-2 infection, to assess the impact of hybrid immune protection on the durability of mucosal immunological responses.

30 Jan 2023

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Dual-action cell therapy engineered to eliminate established tumors and train the immune system to eradicate primary tumor and prevent cancer’s recurrence.

30 Jan 2023

Study shows COVID-19 induces body fat and other metabolic changes

In a recent study published in the journal Cureus, researchers explored the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and levels of serum insulin, body fat distribution, and insulin resistance (IR) estimated by homeostasis model assessment (HOMA).

29 Jan 2023

Study evaluates SARS-CoV-2-specific antibody response in human milk

In a recent study published in the journal Communications Biology, researchers investigated the effect of the coronavirus disease 2019 (COVID-19) vaccine booster on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies in the milk of lactating women. Additionally, they explored whether the booster-induced antibody response differed from the homologous and heterologous boosting schedule of their primary vaccination.

29 Jan 2023

Keto diet as a PCOS treatment

A recent study explores the role of the ketogenic diet in the treatment of polycystic ovarian syndrome.

29 Jan 2023

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

A recent study evaluates the presence of SARS-CoV-2 in children’s tonsils during the COVID-19 pandemic.

29 Jan 2023

Antiviral activity of natural flavonoids against various coronaviruses

A recent study describes the binding affinity and docking sites of several natural compounds, as well as their inhibitory activity against 3CLpro.

29 Jan 2023

Serotonin can potentially accelerate degenerative mitral regurgitation, study says

Serotonin can impact the mitral valve of the heart and potentially accelerate a cardiac condition known as degenerative mitral regurgitation, according to a new study led by researchers at Columbia University's Department of Surgery in collaboration with the Pediatric Heart Valve Center at Children's Hospital of Philadelphia, the University of Pennsylvania, and the Valley Hospital Heart Institute.

29 Jan 2023

Protein C News and Research

New discovery about microglia heralds myriad possibilities for treating neurodegenerative diseases

Researchers discover mechanism underlying the development and intensification of cancer treatment-related pain

New EV platform could help streamline the development and delivery of vaccines worldwide

New candidate molecule could become an effective non-hormonal male contraceptive

Novel class of sulfonamides to block malaria transmission

Direct stochastic optical reconstruction microscopy combined with different labeling approaches for the visualization and quantification of ACE2 on different cells

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Does a second monovalent SARS-CoV-2 mRNA booster increase neutralizing activity to Omicron variants in nursing home residents and healthcare workers?

A baby spent 36 days in an in-network NICU. Why did the hospital next door send a bill?

Study suggests robust lung mucosal immunity against SARS-CoV-2 can be better achieved through hybrid immunity, as opposed to peripheral vaccination alone

Scientists Develop a Cancer Vaccine to Simultaneously Kill and Prevent Brain Cancer

Study shows COVID-19 induces body fat and other metabolic changes

Study evaluates SARS-CoV-2-specific antibody response in human milk

Keto diet as a PCOS treatment

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

Antiviral activity of natural flavonoids against various coronaviruses

Serotonin can potentially accelerate degenerative mitral regurgitation, study says

Researchers discover how measles virus can cause a rare but fatal neurological disorder

Activated neutrophils can become potent cancer fighters

Protein adduction and p53 tumor suppressor inhibition

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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