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Catalent expands OneBio® suite for integrated development, manufacturing and supply across biologic modalities

Catalen today announced that it has expanded its integrated development, manufacturing and supply solution, OneBio® Suite, across a range of biologic modalities, including antibody and recombinant proteins, cell and gene therapies, and mRNA.

From Catalent 16 Jun 2023

New research finds most women diagnosed with early breast cancer can expect to become long-term survivors

Researchers reported longitudinal outcomes among British women suffering from early invasive-type breast tumors as their initial tumor and those initially treated by surgical methods such as conservative surgery or mastectomy.

16 Jun 2023

Is maternal obsessive-compulsive disorder associated with adverse pregnancy, delivery, and neonatal outcomes?

Researchers assessed the correlation between maternal OCD and pregnancy outcomes.

16 Jun 2023

$Fruquintinib improved survival in patients with refractory metastatic colorectal cancer$

Fruquintinib improved survival in patients with refractory metastatic colorectal cancer

Researchers from The University of Texas MD Anderson Cancer Center reported study results showing that the targeted therapy fruquintinib significantly improved overall survival (OS) and progression-free survival (PFS) in patients with refractory metastatic colorectal cancer.

16 Jun 2023

No improvement in freedom from progression rates for patients: Study

Results from the NRG Oncology NRG-RTOG 0232 clinical trial adding external beam radiotherapy (EBRT) to brachytherapy (BT) in men with intermediate-risk prostate cancer indicate that there was no improvement in freedom from progression (FFP) rates for patients.

16 Jun 2023

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

A new therapy is on the horizon for patients with metastatic colorectal cancer who have run out of treatment options.

16 Jun 2023

$11.7M from Department of Defense to fund research on discovering a treatment for hydrocephalus

Researchers at the School of Science at IUPUI will lead two grants totaling $11.7 million from the U.S. Department of Defense to fund research on discovering a drug treatment for hydrocephalus, a condition commonly associated with complications from traumatic brain injury that causes cerebrospinal fluid to accumulate in the brain.

15 Jun 2023

Destroying the tether of shattered chromosomal fragments may help prevent cancerous mutations

Healthy cells work hard to maintain the integrity of our DNA, but occasionally, a chromosome can get separated from the others and break apart during cell division.

15 Jun 2023

$1.9 million grant awarded to explore the effect of antifungal drugs in Crohn's patients

Dr. Iliyan D. Iliev, an associate professor of immunology in medicine in the Division of Gastroenterology and Hepatology, co-director of the Microbiome Core and a member of the Jill Roberts Institute for Research in Inflammatory Bowel Disease (IBD) at Weill Cornell Medicine, is the lead investigator on a grant to Weill Cornell Medicine from The Leona M. and Harry B. Helmsley Charitable Trust to target pathogenic fungi in patients with Crohn's disease.

15 Jun 2023

Bempedoic acid may offer an alternative to the popular cholesterol-lowering drugs

A medication called bempedoic acid reduced the risk of cardiac events as well as statins and may offer an alternative to the popular cholesterol-reducing medications, according to industry-supported research being presented Thursday at ENDO 2023, the Endocrine Society's annual meeting, in Chicago, Ill.

15 Jun 2023

New approach improves diagnosis of limb-girdle muscular dystrophy

It's not easy to distinguish between the dozens of subtypes of limb girdle muscular dystrophy - a rare, genetic muscle disease characterized by weakness in the hips and shoulders that causes difficulty walking and lifting the arms.

15 Jun 2023

Review: Pathophysiology, diagnosis and management of carcinoid heart disease

Announcing a new article publication for Cardiovascular Innovations and Applications journal.

15 Jun 2023

Promising emerging treatment for cardiac arrest patients yields similar results to targeted standard care

A promising emerging treatment (hypercapnia) for comatose adult cardiac arrest patients has been found to yield similar results to current treatment, in a new study published today in the prestigious medical journal New England Journal of Medicine.

15 Jun 2023

$Study: Hip fracture cases estimated to nearly double by 2050$

Study: Hip fracture cases estimated to nearly double by 2050

An international group of researchers led by the Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), and including Douglas P Kiel, MD, MPH, Director Musculoskeletal Research Center, Marcus Institute for Aging Research, Hebrew SeniorLife, and Professor of Medicine, Harvard Medical School, evaluated the secular trends in hip fracture incidence, treatment patterns following a hip fracture, and all-cause mortality in 19 countries and regions from 2005 to 2018.

15 Jun 2023

Routine testing may help to reduce health disparities for people with peripheral artery disease

Low-cost, routine testing may help to reduce disparities and health care costs for people with peripheral artery disease (PAD), according to a new scientific statement from the American Heart Association, published today in the Association's flagship peer-reviewed journal Circulation.

15 Jun 2023

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Researchers examined the serum proteome of unvaccinated adults who had PASC.

15 Jun 2023

Measuring the receipt of medications and behavioral health services for AUD

Heavy drinking commonly begins in adolescence and is a known risk factor for the development of alcohol use disorder (AUD). Data from adult clinical trials suggest offering evidence-based medications for AUD to younger adults could promote their engagement in treatment and improve clinical outcomes.

15 Jun 2023

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Three young patients with relapsed T-cell leukemia have now been treated with base-edited T-cells, as part of a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

15 Jun 2023

Light exercise speeds healing after a concussion

People who did light exercise within 48 hours after a concussion saw their symptoms resolve in about half the time as those who waited more than a week to exercise, a new University of Michigan study found.

14 Jun 2023

Exploring how Bourbon virus-carrying ticks travel through wildlife and to people

On a cold spring morning, Washington University in St. Louis virologist Jacco Boon, PhD, and wildlife ecologist Solny Adalsteinsson, PhD, flap and drag a large white flag through a woodsy area on the western edge of St. Louis County. Boon, an associate professor of medicine in infectious diseases at Washington University School of Medicine in St. Louis, and Adalsteinsson, a senior scientist at the university's Tyson Research Center, are looking for lone star ticks that carry the potentially deadly Bourbon virus.

14 Jun 2023

Therapy News and Research

Catalent expands OneBio® suite for integrated development, manufacturing and supply across biologic modalities

New research finds most women diagnosed with early breast cancer can expect to become long-term survivors

Is maternal obsessive-compulsive disorder associated with adverse pregnancy, delivery, and neonatal outcomes?

Fruquintinib improved survival in patients with refractory metastatic colorectal cancer

No improvement in freedom from progression rates for patients: Study

New selective targeted therapy for metastatic colorectal cancer prolongs overall survival

$11.7M from Department of Defense to fund research on discovering a treatment for hydrocephalus

Destroying the tether of shattered chromosomal fragments may help prevent cancerous mutations

$1.9 million grant awarded to explore the effect of antifungal drugs in Crohn's patients

Bempedoic acid may offer an alternative to the popular cholesterol-lowering drugs

New approach improves diagnosis of limb-girdle muscular dystrophy

Review: Pathophysiology, diagnosis and management of carcinoid heart disease

Promising emerging treatment for cardiac arrest patients yields similar results to targeted standard care

Study: Hip fracture cases estimated to nearly double by 2050

Routine testing may help to reduce health disparities for people with peripheral artery disease

Molecular insights into long COVID: serum proteome reveals dominant signaling pathways

Measuring the receipt of medications and behavioral health services for AUD

New base-edited T-cells proven effective to treat lymphoblastic leukemia

Light exercise speeds healing after a concussion

Exploring how Bourbon virus-carrying ticks travel through wildlife and to people

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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