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Study demonstrates new method to synthesize gold nanoparticles in cancer cells

Dipanjan Pan, professor of chemical, biochemical, and environmental engineering at UMBC, and collaborators published a seminal study in Nature Communications that demonstrates for the first time a method of biosynthesizing plasmonic gold nanoparticles within cancer cells, without the need for conventional bench-top lab methods.

12 Sep 2020

Combined immunotherapy approaches increase the effectiveness of cancer treatment

Cancer immunotherapy is the manipulation of the immune responses naturally present in the human body to fight cancer.

11 Sep 2020

New antitumor vaccines control melanoma growth in preclinical models

Combining their expertise in protein engineering and synthetic DNA technology, scientists at The Wistar Institute successfully delivered nanoparticle antitumor vaccines that stimulated robust CD8 T cell immunity and controlled melanoma growth in preclinical models.

11 Sep 2020

Effective, simple, safe self-amplifying RNA vaccines

A recent review paper in the journal Current Opinion in Virology in September 2020 shows how a new generation of RNA vaccines called self-amplifying RNA vaccines are more potent than conventional mRNA vaccines and could hold the key to the global production of cost-effective potent COVID-19 vaccines.

11 Sep 2020

Study sheds light on how interferon-gamma drives response to immunotherapy in melanoma

A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center sheds light on how interferon-gamma (IFN-y), an immune response-stimulating signaling molecule that helps activate immune cells, guides the treatment response in people with advanced melanoma who are treated with one of the leading immunotherapies - immune checkpoint blockade.

10 Sep 2020

DLnano-vaccines may be a promising strategy for cancer immunotherapy

Researchers designed DLnano-vaccines displaying 60 copies of protein parts derived from the melanoma-specific antigens Trp2 and Gp100 and tested these in mouse models of melanoma, observing prolonged survival that depended on CD8 T cell activation both in therapeutic and prophylactic settings.

10 Sep 2020

Validation of AI tools for cancer immunotherapy may be a step closer

For Artificial Intelligence (AI) tools being developed at Case Western Reserve University to have impact in the fight against cancer, they're going to have to be validated in rigorous human clinical trials.

10 Sep 2020

Novel liver cancer treatment could shrink tumors in a mouse model

Hepatocellular carcinoma is a common liver cancer with poor prognosis. With symptoms not discovered until later stages, it is considered the most fatal malignant liver cancer worldwide.

10 Sep 2020

Brazilian red propolis contains substances with anti-cancer properties

Brazilian red propolis found in beehives along the coast and mangroves in the Northeast region contains two substances with anti-cancer properties. In laboratory tests, they considerably reduced the proliferation of ovarian, breast, and brain cancer cells

10 Sep 2020

Study uncovers genetic vulnerability in breast cancers tumors

The study, published in the scientific journal Nature, has uncovered a genetic vulnerability present in nearly 10% percent of all breast cancers tumours, and found a way to target this vulnerability and selectively kill cancer cells.

9 Sep 2020

Common diabetes drug controls aspects of inflammation in mice

The diabetes drug metformin--derived from a lilac plant that's been used medicinally for more than a thousand years--has been prescribed to hundreds of millions of people worldwide as the frontline treatment for type 2 diabetes.

9 Sep 2020

Novel drug could improve life expectancy and quality for patients with hard-to-treat cancers

The Sheffield researchers founded the spin-out Modulus Oncology with a team of experienced biotech entrepreneurs to fast-track the drug into clinical testing within two years.

9 Sep 2020

New drug can enhance life expectancy and quality for patients with hard-to-treat cancers

A new drug which could improve life expectancy and quality for patients with hard-to-treat cancers, such as pancreatic cancer and relapsed breast cancer, has been invented by scientists at the University of Sheffield.

9 Sep 2020

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

The cover for issue 36 of Oncotarget features, "Knockdown of APOBEC3B is associated with a lower tumor growth in an adrenocortical carcinoma xenograft mouse model," by Gara, et al. which reported that the role of APOBEC3B in adrenocortical carcinoma and the mechanisms through which its expression is regulated in cancer are not fully understood.

9 Sep 2020

New combination therapy helps fight cancer

Radiation causes key changes to immune cells in kidney cancer tumors.T cells in tumors are expanded in blood shortly after radiation, then decrease.

9 Sep 2020

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Hepatocellular carcinoma is a particularly stubborn form of cancer with few treatments and a high mortality rate.

8 Sep 2020

Six genomics research projects receive grants to address the role of ethnicity in major cancers

Leading cancer scientists working with the New York Genome Center (NYGC) announced today that grants are being awarded to fund six projects that address the role of ethnicity in several major cancer types, taking advantage of the diversity of patients being treated at health care institutions throughout the New York City area.

8 Sep 2020

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Researchers at Tel Aviv University, led by Prof. Ronit Satchi-Fainaro of TAU's Department of Physiology and Pharmacology at the Sackler School of Medicine, have developed an innovative nanotechnological drug delivery system that significantly enhances the effectiveness of treatment for the aggressive skin cancer melanoma.

8 Sep 2020

Researchers aim to improve digital thermal imaging as a tool for monitoring cancer

Thermal imaging has been available for decades to detect temperature differences on the skin that could signal breast cancer without exposing patients to radiation, although the method is not as reliable as mammography.

8 Sep 2020

Lack of oxygen can trigger tumor metastases

Metastases are formed by cancer cells that break away from the primary tumor. A research group at the University of Basel has now identified lack of oxygen as the trigger for this process.

8 Sep 2020

Tumor News and Research

Study demonstrates new method to synthesize gold nanoparticles in cancer cells

Combined immunotherapy approaches increase the effectiveness of cancer treatment

New antitumor vaccines control melanoma growth in preclinical models

Effective, simple, safe self-amplifying RNA vaccines

Study sheds light on how interferon-gamma drives response to immunotherapy in melanoma

DLnano-vaccines may be a promising strategy for cancer immunotherapy

Validation of AI tools for cancer immunotherapy may be a step closer

Novel liver cancer treatment could shrink tumors in a mouse model

Brazilian red propolis contains substances with anti-cancer properties

Study uncovers genetic vulnerability in breast cancers tumors

Common diabetes drug controls aspects of inflammation in mice

Novel drug could improve life expectancy and quality for patients with hard-to-treat cancers

New drug can enhance life expectancy and quality for patients with hard-to-treat cancers

Study sheds new light on function and regulation of APOBEC3B in adrenocortical carcinoma

New combination therapy helps fight cancer

Combination of gas embolization and chemotherapy can lead to complete tumor regression

Six genomics research projects receive grants to address the role of ethnicity in major cancers

Nanotechnological drug delivery system enhances the effectiveness of melanoma treatment

Researchers aim to improve digital thermal imaging as a tool for monitoring cancer

Lack of oxygen can trigger tumor metastases

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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