Antigen News and Research

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Discovery of key immune system molecules that helps determine how effectively a person resists HIV infection

A team of researchers based partly in South Africa has identified a key set of immune system molecules that helps determine how effectively a person resists infection with human immunodeficiency virus (HIV).

8 Dec 2004

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

"All cancers are marked by some form of DNA replication gone awry, so a basic understanding of DNA replication is of paramount importance to those designing cancer-fighting drugs,"

8 Dec 2004

First live imaging of specialized immune system cells reveals new clues about body’s security system

To keep the body safe, the immune system enlists more than one form of protection. A circulating task force of immune system cells monitors the body’s periphery, and sends information back to field command centers — the lymph nodes — located at pivotal traffic points.

6 Dec 2004

Alliance to develop and commercialize fully-human anti-anthrax antibody

MDX-1303 was developed by Medarex using its UltiMAb Human Antibody Development System, and this antibody is currently in preclinical development by Medarex for use against human anthrax infection.

6 Dec 2004

Fossil record of the human immune system reveals antibodies that block cancer metastasis

A team of researchers at The Scripps Research Institute has reconstructed the "fossil record" of the immune systems of a group of human cancer patients to investigate if they had ever produced antibodies against their disease.

4 Dec 2004

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

A new study published in the New England Journal of Medicine confirms that stem cells derived from the umbilical cords of newborn babies are a viable and effective transplant source for thousands of leukemia patients who have no other treatment option.

24 Nov 2004

Scientists have determined the crystal structure of a protein kinase C (PKC) isozyme

This structure should prove extremely useful in the rational design of small molecule inhibitors of PKCÈ, which has been implicated in T-cell mediated disease processes including inflammation and autoimmunity.

19 Nov 2004

Transport route explain why peanuts are one of the most allergenic foods

A UK scientist has discovered the route and type of transport taken by peanut proteins through the gut to the immune system. This route favours an immune response, which helps explain why peanuts are one of the most allergenic foods.

18 Nov 2004

Prevalence of occult HBV in hemodialysis patients is 4 to 5 times higher than standard HBsAg testing would suggest

Some kidney dialysis patients contract hepatitis B virus (HBV) during the course of their treatment, possibly from other members of the dialysis population with occult HBV.

8 Nov 2004

VaxGen gets $877.5 million to supply 75 million doses of anthrax vaccine

VaxGen announced today that the U.S. government has awarded the company an $877.5 million contract to supply 75 million doses of anthrax vaccine for civilian defense.

4 Nov 2004

New understanding of the role viruses play in the development of autoimmune diseases

Researchers at the La Jolla Institute for Allergy & Immunology have added a significant milestone to scientific understanding of the role viruses play in the development of autoimmune diseases, such as diabetes.

4 Nov 2004

European approval for Taxotere (docetaxel) in prostate cancer

Aventis, part of the sanofi-aventis Group announced today that the European Commission has approved Taxotere (docetaxel) Injection Concentrate for use in combination with prednisone as a treatment for men with androgen-independent (hormone- refractory) metastatic prostate cancer.

4 Nov 2004

Study aims to improve information and support for older men with prostate cancer

The Centre for Health Services Studies (CHSS) at the University of Kent, England is currently engaged in an exploratory study of the information and support needs for men aged 75+ with prostate cancer.

4 Nov 2004

$73 million to tackle infectious diseases such as West Nile virus and influenza

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded 14 contracts totaling more than $73 million to fund the Large-Scale Antibody and T Cell Epitope Discovery Program, an initiative aimed at quickly identifying the regions of selected infectious agents that elicit immune reactions.

1 Nov 2004

Scientists have uncovered a significant new link in the chain of immune system events through which estrogen prevents bone loss

Through research in mice, the scientists discovered that an immune signaling molecule called type b transforming growth factor (TGFb) is responsible for a cascade of events that leads estrogen to prevent bone loss.

29 Oct 2004

Study suggests safer immunization approach to Alzheimer's

Researchers at the University of Illinois at Chicago have had preliminary success with a method of immunization intended to dissolve the plaques in brain tissue that are associated with Alzheimer's disease.

28 Oct 2004

QIMR researchers have received a 5 year grant to develop a vaccine against Group A streptococcus

QIMR researchers have received a 5 year grant from the National Institutes of Health in the USA to develop a vaccine against Group A streptococcus. This extremely prestigious grant makes QIMR one of the most successful recipients of NIH funding in Australia.

18 Oct 2004

Presentation of the most recent and advanced work in the rapidly progressing field of fertility preservation

Each year approximately 50,000 women under the age of 40 are diagnosed with breast cancer. Treatments vary but most involve the administration of chemotherapeutic agents or radiation which can disrupt ovarian function or damage a patient’s eggs.

18 Oct 2004

Malaria vaccine candidate looks extremely promising

In a proof-of-concept study published this week in The Lancet, researchers report that GlaxoSmithKline's RTS,S/AS02A malaria vaccine candidate protected a significant percentage of children against uncomplicated malaria, infection, and even severe forms of the disease for at least six months.

16 Oct 2004

Prostate cancer patients who no longer respond to hormone therapy may benefit from a combination of docetaxel and estramustine

Prostate cancer patients whose cancer has spread to other parts of the body and who no longer respond to hormone therapy may benefit from a combination of the cancer drugs docetaxel and estramustine, according to a new study published in the Oct. 8 issue of the New England Journal of Medicine.

8 Oct 2004

Antigen News and Research

Discovery of key immune system molecules that helps determine how effectively a person resists HIV infection

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

First live imaging of specialized immune system cells reveals new clues about body’s security system

Alliance to develop and commercialize fully-human anti-anthrax antibody

Fossil record of the human immune system reveals antibodies that block cancer metastasis

Stem cells derived from umbilical cords are a viable and effective transplant source for thousands of leukemia patients

Scientists have determined the crystal structure of a protein kinase C (PKC) isozyme

Transport route explain why peanuts are one of the most allergenic foods

Prevalence of occult HBV in hemodialysis patients is 4 to 5 times higher than standard HBsAg testing would suggest

VaxGen gets $877.5 million to supply 75 million doses of anthrax vaccine

New understanding of the role viruses play in the development of autoimmune diseases

European approval for Taxotere (docetaxel) in prostate cancer

Study aims to improve information and support for older men with prostate cancer

$73 million to tackle infectious diseases such as West Nile virus and influenza

Scientists have uncovered a significant new link in the chain of immune system events through which estrogen prevents bone loss

Study suggests safer immunization approach to Alzheimer's

QIMR researchers have received a 5 year grant to develop a vaccine against Group A streptococcus

Presentation of the most recent and advanced work in the rapidly progressing field of fertility preservation

Malaria vaccine candidate looks extremely promising

Prostate cancer patients who no longer respond to hormone therapy may benefit from a combination of docetaxel and estramustine

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

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Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

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Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics