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New gene therapy strategy shows promise for Parkinson's disease

Researchers from the Shenzhen Institute of Advanced Technology (SIAT) of the Chinese Academy of Sciences (CAS) and their collaborators have developed a gene therapy strategy to selectively manipulate Parkinson's disease-affected circuitry and attenuate the core motor symptoms of Parkinson's disease in rodent and nonhuman primate animals.

2 Nov 2023

New mechanism discovered for aspirin's cancer-fighting properties

LMU researchers have identified a signaling pathway by which aspirin can inhibit colorectal cancer.

2 Nov 2023

LMU medical scientists discover new mechanism of alarmin release

LMU medical scientists have demonstrated that important pro-inflammatory mediators are released into the bloodstream through tiny pores in the cell membrane at a very early stage of the immune response.

2 Nov 2023

Study uncovers how sex differences emerge and evolve in animals

Researchers at the Francis Crick Institute and Heidelberg University in Germany have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

2 Nov 2023

Science, Innovation, and Xenotransplantation: A Discussion with Dr. Wenning Qin

In this interview, we delve deep into the pioneering world of xenotransplantation and the evolving landscape of gene editing.

2 Nov 2023

Study uncovers link between salt-adding habits and type 2 diabetes

A recent study explored the possible interaction of added salt in food with the rate of new type 2 diabetes mellitus (T2DM) to understand the contribution of long-term sodium intake to diabetes incidence.

2 Nov 2023

Mast cell receptor linked to alcohol withdrawal-associated headaches

Researchers investigate the role of the mast-cell-specific receptor Mas-related G-protein-coupled receptor B2 (MrgprB2) in alcohol-withdrawal-induced headaches.

2 Nov 2023

Study sheds light on origins of breast cancer in people with BRCA2 mutations

A pioneering study led by Professor Ashok Venkitaraman from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore and Dr Mona Shehata from the University of Cambridge (UK) has uncovered vital insights into the distinct effects of BRCA2 mutations on breast tissue cells, shedding light on early breast cancer development in people with BRCA2 mutations.

1 Nov 2023

Existing drug could be repurposed to treat type 1 diabetes, study suggests

Type 1 diabetes is an autoimmune disease that causes the body's immune system to attack and destroy insulin-producing beta cells in the pancreas. Traditional management of type 1 diabetes has primarily involved replacing the missing insulin with injections which, though effective, can be expensive and burdensome.

1 Nov 2023

Cancer neuroscience: A new frontier in cancer treatment

Cancer cells hijack normal biological processes, allowing them to multiply. For example, tumors spur construction of new blood vessels, building themselves "highways" to supply nutrients.

1 Nov 2023

$13M NIH grant funds research to rejuvenate immune system in older adults

University of Arizona Health Sciences researchers received a $13.1 million grant from the National Institute on Aging to continue studies aimed at rejuvenating the immune system of older people in order to improve health throughout the lifespan.

1 Nov 2023

Repurposing of DFMO could lead to innovative therapies for type 1 diabetes

A recent study led by Indiana University School of Medicine in collaboration with the University of Chicago Medicine presents exciting future possibilities for the management of type 1 diabetes and the potential reduction of insulin dependency.

1 Nov 2023

Highly sensitive blood test shows promise for early detection of common deadly cancers

Most cancers become deadly by keeping a low profile, causing no symptoms until they're too advanced to treat. Ovarian and gastroesophageal cancers are among the most notorious for this sly disease progression, often leading to late-stage diagnoses.

1 Nov 2023

Study finds health care barriers for most pet owners with HIV

People living with HIV may face hard choices when balancing their own health needs with caring for a pet, a study led by a University of Florida College of Public Health and Health Professions researcher finds.

1 Nov 2023

Clinical trial demonstrates the effectiveness of ALS drug in treating people with acute spinal cord injuries

A small clinical trial with a pharmacokinetic sub-study, led by a world-renowned pharmacologist at the University of Houston, has demonstrated the promising effectiveness of the drug Riluzole for improving functionality in people with acute spinal cord injuries (SCI) if the drug is taken within 12 hours post-injury.

1 Nov 2023

Major new campaign launched in the UK to encourage flu and COVID-19 vaccinations

The UK Health Security Agency (UKHSA), Department of Health and Social Care and NHS England are urging those eligible who've not yet come forward for the flu and COVID-19 vaccines to 'get winter strong' and join the millions of others in taking up the offer ahead of the festive and new year season when flu and COVID-19 are expected to peak.

1 Nov 2023

New drug shows promise in killing cancer cells with genetic vulnerability

Imagine the body's cells are well-behaved students in the classroom. The "teachers" are tumor suppressor genes, and they make sure cells follow the rules. But when tumor suppressor genes are away, cells may go astray.

1 Nov 2023

New gene editing method creates first mice with human-like COVID-19

Researchers have genetically engineered the first mice that get a human-like form of COVID-19, according to a study published online November 1 in Nature.

1 Nov 2023

How to optimize nuclei extraction & counting for single cell sequencing

In this interview, News Medical talks to DeNovix about the best way to prepare nuclei samples before single cell sequencing workflows and optimize nuclei extraction.

From DeNovix Inc. 1 Nov 2023

PacBio announces Kinnex RNA Kits, further scaling HiFi Sequencing in Full-Length RNA, Single-Cell RNA and 16S rRNA applications

PacBio today announced it has begun taking orders for its groundbreaking Kinnex RNA kits, which increase throughput for full-length RNA, single-cell RNA, and 16S rRNA sequencing on PacBio’s long-read sequencing systems to enable large-scale studies at a resolution difficult to attain with short-read RNA sequencing.

From PacBio 1 Nov 2023