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Study highlights the need for caution while using CRISPR-based gene therapies

A comprehensive study - conducted by researchers at Sanford Burnham Prebys, the National Cancer Institute (NCI) and other groups - has shown that gene editing, specifically gene knockout (KO), with CRISPR -Cas9 can favor cells with mutated forms of genes linked to cancer.

11 Nov 2021

RT-LAMP coupled solid-state nanopores for SARS-CoV-2 detection

Researchers discuss a highly sensitive, specific, and rapid SARS-CoV-2 detection platform by coupling the RT-LAMP with glass nanopore sensors.

11 Nov 2021

Urothelial cancers in Lynch Syndrome patients can be detected using a simple, cheap urine test

Researchers have shown for the first time that it is possible to detect signs of urothelial cancer using a simple, postal, urine test in Lynch Syndrome (LS) patients who are at high risk of developing tumors.

11 Nov 2021

New study offers genetic insight into why we look the way we do

Which genes control the defining features that make us look as we do? And how do they make it happen?

11 Nov 2021

Whole senome sequencing can effectively secure a diagnosis for people with rare diseases

A world-first scientific study, published today in the New England Journal of Medicine, has shown that whole genome sequencing can uncover new diagnoses for people across the broadest range of rare diseases investigated to date and could deliver enormous benefits across the NHS.

10 Nov 2021

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

10 Nov 2021

Identifying an important protein for motor coordination

News-Medical speaks to Professor Jorge Ruas about how he has identified an important protein involved in motor coordination.

10 Nov 2021

Cell-based viral replication system for screening of SARS-CoV-2 drugs

The current study reports a SARS-CoV-2 replicon system within stable cell lines that can be cultured with ease in a standard biosafety level 2 laboratory.

10 Nov 2021

Western boom cities see spike in harmful ozone

The reduction of harmful ground-level ozone across most of the U.S. over the past several decades has been an air pollution success story.

10 Nov 2021

New epigenetic editing technique may advance the treatment of many diseases

Type 1 diabetes, rheumatoid arthritis, and cancer are just some of the disorders associated with specific genes not "turning on" and "turning off" as they should.

9 Nov 2021

Researchers investigate how intestinal bacteria distribute metabolic products in membrane vesicles

Bacteria in the intestine pack a wide spectrum of their biomolecules into small capsules. These are transported via the bloodstream to various organs in the body and even absorbed and processed by nerve cells in the brain.

9 Nov 2021

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

In a groundbreaking study of people living with HIV, University of Alberta researchers found that elusive white blood cells called neutrophils play a role in impaired T cell functions and counts, as well as the associated chronic inflammation that is common with the virus.

9 Nov 2021

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

A new study explores the potential of MV-based vaccines targeting the S protein of SARS-CoV-2.

9 Nov 2021

SARS-CoV-2 infection regulates protein arginylation

A new study explores the role of arginylation during SARS-CoV-2 infection.

9 Nov 2021

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Leptin, a molecule produced by fat cells, appears to cancel out the effects of the estrogen-blocking therapy tamoxifen, a drug commonly used to treat and prevent breast cancers, suggests a new study led by researchers from the Johns Hopkins Kimmel Cancer Center.

9 Nov 2021

Scientists discover gene responsible for doubling the risk of respiratory failure from COVID-19

Scientists at Oxford University have identified the gene responsible for doubling the risk of respiratory failure from COVID-19.

9 Nov 2021

Multiplex network offers a systematic approach to study rare, uncharacterized diseases

Rare diseases are usually caused by a single genetic defect. Nevertheless, the search for the cause and the assessment of the effects is highly complex and difficult.

9 Nov 2021

Pregnant women’s humoral response is dependent on SARS-CoV-2 strain

The current study from Israel discusses the change in antibody response with the trimester of infection and the infecting variant.

9 Nov 2021

Non-invasive breathing support to treat COVID-19 does not pose higher risk of infection

New research has found that the use of non-invasive breathing support to treat moderate to severe COVID-19 infection, isn’t linked to a heightened infection risk, as currently thought.

9 Nov 2021

Pfizer-BioNTech COVID-19 vaccine is associated with lower viral load in breakthrough infections

Several vaccines have been rapidly developed to help control the COVID-19 pandemic, including the BNT162b2 vaccine (Pfizer/BioNTech). This severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine has been shown in both clinical trials and in the real world to be highly efficacious in preventing infection, symptoms, hospitalizations, severe disease, and death related to coronavirus disease (COVID-19).

9 Nov 2021

Genes News and Research

Study highlights the need for caution while using CRISPR-based gene therapies

RT-LAMP coupled solid-state nanopores for SARS-CoV-2 detection

Urothelial cancers in Lynch Syndrome patients can be detected using a simple, cheap urine test

New study offers genetic insight into why we look the way we do

Whole senome sequencing can effectively secure a diagnosis for people with rare diseases

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Identifying an important protein for motor coordination

Cell-based viral replication system for screening of SARS-CoV-2 drugs

Western boom cities see spike in harmful ozone

New epigenetic editing technique may advance the treatment of many diseases

Researchers investigate how intestinal bacteria distribute metabolic products in membrane vesicles

Elusive white blood cells play a role in impaired T cell functions and counts in people with HIV

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

SARS-CoV-2 infection regulates protein arginylation

Fat-secreted molecule may cancel out the effects of common breast cancer treatment

Scientists discover gene responsible for doubling the risk of respiratory failure from COVID-19

Multiplex network offers a systematic approach to study rare, uncharacterized diseases

Pregnant women’s humoral response is dependent on SARS-CoV-2 strain

Non-invasive breathing support to treat COVID-19 does not pose higher risk of infection

Pfizer-BioNTech COVID-19 vaccine is associated with lower viral load in breakthrough infections

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