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Researchers uncover novel and non-invasive way to track dengue infection

Commonly used to detect solid tumors, positron emission tomography (PET) paired with the glucose metabolism probe, fluorodeoxyglucose (FDG), is considered 'old' technology in the field of cancer.

6 Jun 2017

Researchers develop new approach to build better blood-brain barrier model

Delivering drugs to the brain is no easy task. The blood-brain barrier -a protective sheath of tissue that shields the brain from harmful chemicals and invaders - cannot be penetrated by most therapeutics that are injected into a person's blood stream.

6 Jun 2017

Tiny microRNA could act as protective mechanism to reduce risk of epileptic seizures, say scientists

A tiny microRNA has been shown to play a beneficial role in protecting the brain from epileptic seizures in specially engineered transgenic mice. Scientists at the Hebrew University of Jerusalem say it could act as a protective mechanism to reduce the risk of epileptic seizures in humans.

5 Jun 2017

Novartis to collaborate with IBM Watson Health for improving outcomes in advanced breast cancer

Novartis today announced a first-of-its-kind collaboration with IBM Watson Health on an initiative to optimize cancer care and improve patient outcomes.

5 Jun 2017

EFMT technology results in greater reduction of major depressive disorder symptoms

A treatment for depression using Emotional Faces Memory Task (EFMT), a technology originally developed by two Mount Sinai researchers, resulted in a significantly greater reduction of major depressive disorder (MDD) symptoms compared to a control group, according to initial clinical results presented at the Society of Biological Psychiatry Annual Scientific Convention on May 19, 2017, in San Diego.

5 Jun 2017

Recommendations to facilitate optimal CGM use and reporting of data in diabetes clinical research

The advantages of continuous glucose monitoring (CGM) for obtaining real-time blood glucose measurements and its ability to detect and even predict hypo- and hyperglycemic events make it a very useful tool for evaluating experimental glucose-lowering drugs and new approaches for treating diabetes.

2 Jun 2017

Researchers find new way to block type 1 diabetes

Researchers at The Jackson Laboratory, Cyteir Therapeutics and collaborating institutions have found a way to protect beta cells from destruction -- achieving a longtime, elusive goal that could lead to therapies preventing type 1 diabetes (T1D).

1 Jun 2017

Differences in uptake of toxins, nutritional elements during late pregnancy and early life linked to ASD risk

Using evidence found in baby teeth, researchers from The Senator Frank R. Lautenberg Environmental Health Sciences Laboratory and The Seaver Autism Center for Research and Treatment at Mount Sinai found that differences in the uptake of multiple toxic and essential elements over the second and third trimesters and early postnatal periods are associated with the risk of developing autism spectrum disorders (ASD), according to a study published June 1 in the journal Nature Communications.

1 Jun 2017

Researchers gain new insights into factors crucial for STIM1 activation

Triggered by decreases in ER Ca2+ level, conformational changes of the endoplasmic reticulum (ER) luminal domain in STIM1 would switch on its cytoplasmic domain (CT) to engage and gate ORAI channels on plasma membrane, resulting in Ca2+ influx.

1 Jun 2017

Phase 2 clinical study examines Alzheimer's disease drug to treat adults with Down syndrome

A phase 2 clinical trial in young adults with Down syndrome of a drug being investigated for the treatment of Alzheimer's disease supports further investigation of its potential.

1 Jun 2017

Case Western Reserve University awarded $6 million grant to continue research on Barrett's Esophagus

The National Cancer Institute recently awarded a $6 million grant to the Case Comprehensive Cancer Center and Case Western Reserve University School of Medicine to continue research on Barrett's Esophagus, a potentially fatal condition caused by long-term acid reflux.

31 May 2017

Brain changes after stroke may lead to increased preference for alcohol, research suggests

Brain changes after stroke may lead to increase in alcohol-seeking behavior, at least in animal models, according to research published Wednesday in the journal Scientific Reports.

31 May 2017

Oxytocin treatment may help overcome drug addiction, study suggests

Many people have suggested that addiction hijacks the body's natural drives in the service of compulsive drug use.

31 May 2017

GW researcher receives NIH funding to explore ways for standardization of cancer genomics data

One of the biggest challenges facing cancer genomics researchers is the lack normalized data on cancer genes. Multitudes of genomics projects have been funded over the years that have resulted in data being placed on several different databases, making a wide array of data and annotations difficult to integrate and compare.

30 May 2017

Clinical study tests 100-year-old drug in children with autism spectrum disorder

In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

26 May 2017

Study: Early-stage breast cancer patients undergo inappropriate tests that may increase financial burden

A study from Fred Hutchinson Cancer Research Center that will be presented at the American Society of Clinical Oncology annual meeting on June 5 in Chicago shows that asymptomatic women who have been treated for early-stage breast cancer often undergo advanced imaging and other tests that provide little if any medical benefit, could have harmful effects and may increase their financial burden.

25 May 2017

Pulmonary thrombosis-on-a-chip enables unprecedented study of blood responses to organ-level injury

The average human pair of lungs is permeated by a network of about 164 feet of blood vessels (roughly the width of a football field), including microscopic blood capillaries, which facilitate the diffusion of oxygen into the bloodstream in exchange for carbon dioxide.

23 May 2017

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

Liver cirrhosis is the 12th leading cause of mortality worldwide and approximately half of those deaths are due to alcohol abuse.

23 May 2017

New anti-viral tool could become game-changer in the fight against MERS

In June 2012, a 60 year-old man with flu-like symptoms walked into a private hospital in Jeddah, Saudi Arabia. Two weeks later, he died from multiple organ failure, becoming the first victim of a mysterious virus that came to be known as Middle East Respiratory Syndrome or MERS.

19 May 2017

New findings could lead to first broadly effective ebolavirus therapies and vaccines

After analyzing the blood of a survivor of the 2013-16 Ebola outbreak, a team of scientists from academia, industry and the government has discovered the first natural human antibodies that can neutralize and protect animals against all three major disease-causing ebolaviruses.

19 May 2017

Therapeutics News and Research

Researchers uncover novel and non-invasive way to track dengue infection

Researchers develop new approach to build better blood-brain barrier model

Tiny microRNA could act as protective mechanism to reduce risk of epileptic seizures, say scientists

Novartis to collaborate with IBM Watson Health for improving outcomes in advanced breast cancer

EFMT technology results in greater reduction of major depressive disorder symptoms

Recommendations to facilitate optimal CGM use and reporting of data in diabetes clinical research

Researchers find new way to block type 1 diabetes

Differences in uptake of toxins, nutritional elements during late pregnancy and early life linked to ASD risk

Researchers gain new insights into factors crucial for STIM1 activation

Phase 2 clinical study examines Alzheimer's disease drug to treat adults with Down syndrome

Case Western Reserve University awarded $6 million grant to continue research on Barrett's Esophagus

Brain changes after stroke may lead to increased preference for alcohol, research suggests

Oxytocin treatment may help overcome drug addiction, study suggests

GW researcher receives NIH funding to explore ways for standardization of cancer genomics data

Clinical study tests 100-year-old drug in children with autism spectrum disorder

Study: Early-stage breast cancer patients undergo inappropriate tests that may increase financial burden

Pulmonary thrombosis-on-a-chip enables unprecedented study of blood responses to organ-level injury

Researchers link intestinal fungi to increased risk of death in patients with alcoholic liver disease

New anti-viral tool could become game-changer in the fight against MERS

New findings could lead to first broadly effective ebolavirus therapies and vaccines

Event guide: The Non-Opioid Pain Therapeutics Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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