Genes News and Research

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Milestone study uncovers genetic risk factors for spine osteoarthritis

Scientists from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed), contributing as part of the 'Genetics of Osteoarthritis (GO)' consortium to the world's largest study of over 800,000 individuals, have identified genetic risk factors - variants associated with SOX5 and CHST3 genes, key regulators of the development of the intervertebral discs, to be implicated in spine osteoarthritis (OA).

8 Nov 2021

Study points to a new, effective treatment option for patients with mesothelioma

Combining the immunotherapy agent durvalumab with the chemotherapy agents pemetrexed and cisplatin or carboplatin may provide a new treatment option for patients who have inoperable pleural mesothelioma, a cancer of the tissues lining the lungs, according to a phase II clinical trial led by researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy.

8 Nov 2021

Discovery of potent neutralizing antibodies against SARS-CoV-2 variants

In a recent study, the researchers identify and characterize mAbs that are effective against the wild-type SARS-CoV-2 strain and B.1.351 variant.

8 Nov 2021

Identification of a candidate effector gene at COVID-19 risk locus

A new study focuses on developing a comprehensive platform to decode the effects of sequence variation identified by GWAS.

8 Nov 2021

Study shows how whole genome sequencing could benefit children with cancer

Unravelling the entire genetic code for each child who has been diagnosed with cancer can give a more accurate diagnosis or reveal new treatment options, according to research presented at the NCRI Festival. These are the results of a pilot study of the process known as whole genome sequencing.

8 Nov 2021

Study looks at how lupus genetics intersects with COVID-19

The study “Interferon pathway lupus risk alleles modulate risk of death from acute COVID-19” was recently published on the preprint medRxiv* server.

8 Nov 2021

Maternal exposure to flame retardants linked with ASD-relevant behavioral traits in offspring

Polybrominated diphenyl ethers, or PBDEs, are a class of fire-retardant chemicals that are ubiquitous. They are found on upholstery, carpets, curtains, electronics, and even infant products.

7 Nov 2021

Scientists create a rapid diagnostic technology to detect SARS-CoV-2

Blending experts from molecular genetics, chemistry and health sciences, researchers at the University of California San Diego have created a rapid diagnostic technology that detects SARS-CoV-2, the coronavirus that causes COVID-19.

6 Nov 2021

“Catching SARS-CoV-2 in the act” – viral infection of nasal mucosa spares nerve cells

A new study discusses the entry of SARS-CoV-2 into the respiratory and olfactory mucosa of the nasal cavity.

4 Nov 2021

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

Many people develop Alzheimer's or other forms of dementia as they get older. However, others remain sharp well into old age, even if their brains show underlying signs of neurodegeneration.

3 Nov 2021

Adaptive immunity in patients infected with SARS-CoV-2 Δ382 Variant

A comprehensive characterization of the immune responses between SARS-CoV-2 infected individuals with wildtype (WT) and Δ382 SARS-CoV-2.

3 Nov 2021

Researchers identify a single protein that balances sugar and fat metabolism in the liver

Keeping everything running smoothly inside the human body is a tricky business that involves a multitude of checks and balances to make sure that an exquisite equilibrium is maintained.

2 Nov 2021

Scientists discover key component of cellular malfunction that contributes to growth of tumors

Scientists have homed in on a crucial step within the sequence of chemical reactions that govern regulation of cell division, proliferation and death, and whose malfunction contributes to the growth of tumors.

2 Nov 2021

Trends in SARS-CoV-2 seroprevalence in Massachusetts

A new study reported findings from a retrospective, de-identified and systematic survey of SARS-CoV-2 seroprevalence among childbearing women in Massachusetts.

2 Nov 2021

Identification of common genes in COVID-19 and COPD

Based on protein-protein interactions, the paper shows the presence of ten genes that overlap between the two illnesses, also shared by several other deadly and debilitating diseases.

2 Nov 2021

Placental cell-type productively infected with SARS-CoV-2

A new preprint describes the development of a new platform for evaluating the risk of SARS-CoV-2 infection in placental tissue.

2 Nov 2021

Study reveals how bone cells form dendrites that are important for maintaining bone strength

Embedded within bone tissue are osteocytes, cells with tree-like projections called dendrites that are important for receiving communication from other cells.

1 Nov 2021

SARS-CoV-2 introduction events in Québec, Canada

Researchers from McGill University have been investigating the number of introduction events in Quebec.

1 Nov 2021

Researchers generate and characterize the hepatic organoid culture system

Organoid technologies have become a powerful emerging tool to model liver diseases, for drug screening, and for personalized treatments.

1 Nov 2021

Areas with higher 1968 influenza pandemic mortality have lower COVID-19 deaths

A new study demonstrates the influence of prior infectious outbreaks in a large population on succeeding pandemic outcomes.

31 Oct 2021

Genes News and Research

Milestone study uncovers genetic risk factors for spine osteoarthritis

Study points to a new, effective treatment option for patients with mesothelioma

Discovery of potent neutralizing antibodies against SARS-CoV-2 variants

Identification of a candidate effector gene at COVID-19 risk locus

Study shows how whole genome sequencing could benefit children with cancer

Study looks at how lupus genetics intersects with COVID-19

Maternal exposure to flame retardants linked with ASD-relevant behavioral traits in offspring

Scientists create a rapid diagnostic technology to detect SARS-CoV-2

“Catching SARS-CoV-2 in the act” – viral infection of nasal mucosa spares nerve cells

MIT researchers identify link between MEF2 gene and cognitive resilience in older individuals

Adaptive immunity in patients infected with SARS-CoV-2 Δ382 Variant

Researchers identify a single protein that balances sugar and fat metabolism in the liver

Scientists discover key component of cellular malfunction that contributes to growth of tumors

Trends in SARS-CoV-2 seroprevalence in Massachusetts

Identification of common genes in COVID-19 and COPD

Placental cell-type productively infected with SARS-CoV-2

Study reveals how bone cells form dendrites that are important for maintaining bone strength

SARS-CoV-2 introduction events in Québec, Canada

Researchers generate and characterize the hepatic organoid culture system

Areas with higher 1968 influenza pandemic mortality have lower COVID-19 deaths

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