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Phase 2 clinical study examines Alzheimer's disease drug to treat adults with Down syndrome

A phase 2 clinical trial in young adults with Down syndrome of a drug being investigated for the treatment of Alzheimer's disease supports further investigation of its potential.

1 Jun 2017

Therapeutic small molecules safely prevent blood clots without excessive bleeding

It may be possible to disrupt harmful blood clots in people at risk for heart attack or stroke without increasing their risk of bleeding, according to a new study published in Nature Communications.

31 May 2017

Clinical trial uses small molecule to treat men with incurable prostate cancer

NewYork-Presbyterian and Weill Cornell Medicine have begun the first clinical trial in the United States that uses a small molecule to treat men with progressive prostate cancer that has spread beyond the prostate and is no longer responding to hormonal therapy.

31 May 2017

Dutch scientists design self-destroying nanomotors to deliver and release drugs

Autonomous targeting and release of drugs at their site of action are desired features of nanomedical systems. Now, a team of Dutch scientists has designed a nanomotor that has these functions: An antitumor drug encapsulated in self-propelled, self-assembled stomatocytes is carried across the cellular membrane and released inside the cell upon a chemical redox signal that disassembles the vesicle membrane.

31 May 2017

Oxytocin treatment may help overcome drug addiction, study suggests

Many people have suggested that addiction hijacks the body's natural drives in the service of compulsive drug use.

31 May 2017

Rice University scientists develop and evaluate analogs of potent cancer fighters

Rice University scientists have developed and evaluated analogs of potent anti-tumor agents known as epothilones using designs and methods that both improve their biological properties and simplify their manufacture.

31 May 2017

TSRI scientists give new superpowers to lifesaving antibiotic

Scientists at The Scripps Research Institute have given new superpowers to a lifesaving antibiotic called vancomycin, an advance that could eliminate the threat of antibiotic-resistant infections for years to come.

30 May 2017

Scripps scientists make important advance in HIV vaccine design

Scientists at The Scripps Research Institute (TSRI) have made another important advance in HIV vaccine design. The development was possible thanks to previous studies at TSRI showing the structures of a protein on HIV’s surface, called the envelope glycoprotein. The scientists used these structures to design a mimic of the viral protein from a different HIV subtype, subtype C, which is responsible for the majority of infections worldwide.

29 May 2017

Scientists discover receptor protein that promotes chronic heart failure

Researchers in Japan have identified a receptor protein on the surface of heart cells that promotes chronic heart failure.

26 May 2017

New NMR machine at TSRI’s Florida campus will help advance drug development process

The Nuclear Magnetic Resonance facility at the Florida campus of The Scripps Research Institute is becoming one of the most advanced in South Florida, thanks to a new $600,000 grant from the National Institutes of Health.

26 May 2017

Clinical study tests 100-year-old drug in children with autism spectrum disorder

In a small, randomized Phase I/II clinical trial (SAT1), researchers at University of California San Diego School of Medicine say a 100-year-old drug called suramin, originally developed to treat African sleeping sickness, was safely administered to children with autism spectrum disorder (ASD), who subsequently displayed measurable, but transient, improvement in core symptoms of autism.

26 May 2017

Researchers discover size-sensing protein that controls glucose uptake and storage in fat cells

Researchers at the University of Iowa have discovered that a molecule which can sense the swelling of fat cells also controls a signaling pathway that allows fat cells to take up and store excess glucose.

25 May 2017

Leica introduces new DMi8 S solution for fast, versatile microscopic imaging of living cells

Leica introduces the DMi8 S, a new complete solution designed to give researchers the ultimate tool for fast, versatile microscopic imaging of living cells allowing scientists to find, observe and interact with living cells like never before.

From Leica Microsystems GmbH 25 May 2017

Molecule discovered in worm spit could offer solution for non-healing wounds

Every day 12 Australian diabetics have a limb amputated because of a non-healing wound. Globally, it's one every 30 seconds.

25 May 2017

BGU researchers redesign portion of FDA-approved drug into new molecule to treat ALS

Ben-Gurion University of the Negev researchers are developing a new therapy for Amyotrophic Lateral Sclerosis using part of an existing FDA-approved drug that restores the central nervous system's (CNS) immune defenses and increases life expectancy.

25 May 2017

Researchers discover new anti-thrombotic drug target for developing more protective blood thinners

Blood platelets shore up open wounds and help cuts heal, but they can also cause heart attacks and strokes when a congealed ball of platelets known as a thrombus breaks free from a site of injury and gets lodged in blood vessels that feed oxygen to the brain or heart.

24 May 2017

Molecule News and Research

Phase 2 clinical study examines Alzheimer's disease drug to treat adults with Down syndrome

Therapeutic small molecules safely prevent blood clots without excessive bleeding

Clinical trial uses small molecule to treat men with incurable prostate cancer

Dutch scientists design self-destroying nanomotors to deliver and release drugs

Oxytocin treatment may help overcome drug addiction, study suggests

Rice University scientists develop and evaluate analogs of potent cancer fighters

TSRI scientists give new superpowers to lifesaving antibiotic

Scripps scientists make important advance in HIV vaccine design

Scientists discover receptor protein that promotes chronic heart failure

New NMR machine at TSRI’s Florida campus will help advance drug development process

Clinical study tests 100-year-old drug in children with autism spectrum disorder

Researchers discover size-sensing protein that controls glucose uptake and storage in fat cells

Leica introduces new DMi8 S solution for fast, versatile microscopic imaging of living cells

Molecule discovered in worm spit could offer solution for non-healing wounds

BGU researchers redesign portion of FDA-approved drug into new molecule to treat ALS

Researchers discover new anti-thrombotic drug target for developing more protective blood thinners

Intranasal oxytocin can influence how individuals with autism perceive emotion in others

U-M research reveals important clues about invasion of polyomaviruses

Study points to new pharmacologic approach to target chemo-resistant lung cancer

Study findings could lead to quick and new way for predicting efficacy of cancer treatments

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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