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Organ-transplant drug may aid in lupus fight

A compound related to a drug used in humans to prevent organ-transplant rejection attacks a key biochemical process in the faulty immune cells of lupus-prone mice, suggesting a possible new approach to combating the disease, UT Southwestern Medical Center researchers have found.

15 Aug 2007

Killer T cell treatment shows promise against cancers in transplant patients

Blood cell donations could be used to treat transplant patients with a particular form of cancer, according to a Cancer Research UK study reported in the journal Blood.

15 Aug 2007

Living donor swap for kidney transplants

New and innovative programs to obtain donor organs have the potential to revolutionize kidney transplantation.

13 Aug 2007

Researchers discover how Bcl-3 protein stops inflammation

Researchers at the University of Pennsylvania School of Medicine recently identified how a regulatory protein called Bcl-3 helps to control the body's inflammation response to infection by interfering a critical biochemical process called ubiquitination.

12 Aug 2007

Staggering costs of end-stage renal disease in U.S.

Recent progress in the prevention and treatment of end-stage renal disease (ESRD) in the United States give reason for "cautious optimism," but skyrocketing costs are a major concern, according to a Special Article in the October Journal of the American Society of Nephrology.

12 Aug 2007

New pathway for inflammation-induced cancer

A well-known inflammatory protein spawns an enzyme that inactivates two tumor-suppressing genes, ultimately triggering production of new blood vessels to nourish breast cancer cells, researchers at The University of Texas M. D. Anderson Cancer Center report in the August edition of the journal Cell .

11 Aug 2007

Chemotherapy and blood stem cell transplantation results in long-term survival for amyloidosis patients

Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center (BUMC) have found that high-dose chemotherapy and blood stem cell transplantation can result in long-term survival for patients diagnosed with primary systemic light chain (AL) Amyloidosis.

8 Aug 2007

Bcl-3 protein regulates inflammation by blocking ubiquitination

8 Aug 2007

Implantable artificial lung

The University of Michigan Medical School laboratory working to develop an implantable artificial lung that can serve as a bridge to lung transplantation is entering the home stretch.

6 Aug 2007

Predicting outcomes before and after liver transplants

The most appropriate system for organ allocation for liver transplants is a subject of continuing debate.

3 Aug 2007

First case of successful ovarian tissue transplantation between two, nonidentical sisters

A woman, whose ovaries had failed due to damage caused by chemotherapy and radiotherapy, has received a successful ovarian transplant from her genetically non-identical sister.

3 Aug 2007

Key signs of appendicitis

A 5-year-old with abdominal pain, nausea and fever may have appendicitis or any of a number of other problems.

3 Aug 2007

Stem cell therapy rescues motor neurons in ALS model

In a study that demonstrates the promise of cell-based therapies for diseases that have proved intractable to modern medicine, a team of scientists from the University of Wisconsin-Madison has shown it is possible to rescue the dying neurons characteristic of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder also known as Lou Gehrig's disease.

3 Aug 2007

Delta-9-tetrahydrocannabinol opens door for virus that causes Kaposi's sarcoma

The major active component of marijuana could enhance the ability of the virus that causes Kaposi's sarcoma to infect cells and multiply, according to a team of researchers at Harvard Medical School.

2 Aug 2007

Aggressive therapy best for certain acute myeloid leukemia patients

A new study suggests that acute leukemia patients whose cancer cells show a genetic change that usually predicts a swift return of the disease following remission may remain disease-free longer when given aggressive therapy.

2 Aug 2007

Woman has successful ovarian transplant from her sister

A woman whose ovaries were damaged by chemotherapy and radiotherapy, has received a successful ovarian transplant from her sister.

1 Aug 2007

Stem cell therapy rescues motor neurons in amyotrophic lateral sclerosis model

31 Jul 2007

Bone marrow restores fertility in female mice

A new study from Massachusetts General Hospital (MGH) researchers confirms that female mice that receive bone marrow transplantation after fertility-destroying chemotherapy can go on to have successful pregnancies throughout their normal reproductive life.

31 Jul 2007

Bio-engineered bladders a step closer to reality

Researchers at the University of York are using an understanding of the special cells that line the bladder to develop ways of restoring continence to patients with serious bladder conditions, including cancer.

31 Jul 2007

Europe approves MIRCERA to treat anaemia

Roche has announced that the European Commission has approved its innovative drug MIRCERA to treat anaemia associated with chronic kidney disease (CKD).

27 Jul 2007