Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Scientists block early step in metastasis of prostate cancer cells

Recent studies have suggested an association between chronic inflammation and cancers of the prostate, colon, stomach and liver.

9 Apr 2008

Blood test in the pipeline for early Parkinson's and Alzheimer's

A company in the U.S. says it has a blood test in the pipeline which is able to detect the early signs of Parkinson's and Alzheimer's disease.

9 Apr 2008

Salivary diagnostics

Accuracy, convenience, and non-invasiveness are the most critical characteristics for any diagnostic tool.

7 Apr 2008

Mitochondria play role in pathogenesis of AD and estrogen-induced neuroprotection

As the major source of free radicals in cells, mitochondria contribute to the high levels of oxidative stress believed to play a role in the pathogenesis of Alzheimer's disease.

7 Apr 2008

New blood test gives early diagnosis of neurodegenerative diseases

A new blood test that can give an early diagnosis of neurodegenerative disease and distinguish between Parkinson's and Alzheimer's disease could be launched this summer, reports Marina Murphy in SCI's Chemistry & Industry magazine.

7 Apr 2008

Continuous oral contraceptives better at easing pain, bleeding

Continuous oral contraceptives may be more effective than the standard 28-day birth control pills in suppressing the ovary, according to researchers.

4 Apr 2008

Satoris enters collaboration to validate early Alzheimer's test

Satoris, Inc., a molecular diagnostics company focused on developing blood-based tests for Alzheimer ' s disease, will shortly begin a collaborative study with the Mayo Foundation for Medical Education and Research (Mayo Clinic) to validate the utility of plasma biomarkers for early detection of mild to moderate Alzheimer ' s disease.

2 Apr 2008

A new way to test for lung cancer

Researchers from Boston University School of Medicine have developed a new “clinicogenomic model” to accurately test for lung cancer.

2 Apr 2008

Eli Lilly starts trial of treatment of mild to moderate Alzheimer's disease

Eli Lilly and Company has announced the start of a Phase III clinical trial studying LY450139, an investigational gamma secretase inhibitor for the treatment of mild to moderate Alzheimer's disease.

1 Apr 2008

New tool to identify the molecular signatures of serious diseases

University of Florida chemists are the first to use a new tool to identify the molecular signatures of serious diseases - without any previous knowledge of what these microscopic signatures or "biomarkers" should look like.

1 Apr 2008

Expansion of monocyte subset could serve as a biomarker for HIV progressions

An increase in the CD163+/CD16+ monocyte subset could be a biomarker for the progression of HIV disease, according to researchers at Temple University.

31 Mar 2008

New method for cancer screening

Ongoing research at Missouri University of Science and Technology has uncovered a new method for the early detection of cancer with the potential to save millions of lives.

31 Mar 2008

Scientists discover how salmonella becomes lethal for AIDS patients

Nearly half of all HIV-positive African adults who become infected with Salmonella die from what otherwise would be a seven-day bout of diarrhea.

25 Mar 2008

Near-infrared light used to detect signs of Alzheimer's disease

A team of researchers in Bedford, Mass. has developed a way of examining brain tissue with near-infrared light to detect signs of Alzheimer's disease.

20 Mar 2008

Disruption of the Contactin 4 gene on chromosome 3 may be linked to autism spectrum disorder

Eli Hatchwell, M.D., Ph.D., Associate Professor of Pathology at Stony Brook University Medical Center, and colleagues have found that a disruption of the Contactin 4 gene on chromosome 3 may be linked to autism spectrum disorder (ASD).

20 Mar 2008

Millionaire leaves millions for research into motor neuron disease

A self-made millionaire Peter Goodenough who died from motor neuron disease (MND) left more than $6 million to the University's Queensland Brain Institute (QBI) to help find a cure for MND.

19 Mar 2008

Compound found in soybeans may halt spread of prostate cancer

A compound found in soybeans almost completely prevented the spread of human prostate cancer in mice, according to a study published in the March 15 issue of Cancer Research, a journal of the American Association for Cancer Research.

17 Mar 2008

Near-infrared light used to detect signs of Alzheimer's disease

A team of researchers in Bedford, Mass. has developed a way of examining brain tissue with near-infrared light to detect signs of Alzheimer's disease.

17 Mar 2008

Artificial butter chemical acetyl harmful to lungs

A new study shows that exposure to a chemical called diacetyl, a component of artificial butter flavoring, can be harmful to the nose and airways of mice.

14 Mar 2008

Simple laboratory test predicts risk of kidney injury after surgery

A simple laboratory test may provide a new way for doctors to identify patients at risk of developing potentially severe acute kidney injury (AKI) after surgery up to three days before the problem would otherwise be detected, reports a pilot study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology .

14 Mar 2008