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Researchers discover cancer-fighting properties in beta blockers

A new study finds that carvedilol, a drug typically used to treat high blood pressure, can protect against the sun-induced cell damage that leads to skin cancer. Researchers serendipitously discovered the beta blocker's cancer-fighting properties after making an error in the lab.

24 Apr 2017

New report suggests innovative approaches for better response to chemical inhalation disasters

Better medical responses to the accidental or intentional release of inhaled toxic chemicals are being developed, but the field faces considerable challenges, according to a new report by an international panel of experts.

21 Apr 2017

UC San Diego Amazonian Center to receive NIH funding for malaria research

The Amazonian Center of Excellence for Malaria Research, headed by Joseph Vinetz, MD, professor of medicine and tropical disease specialist at University of California San Diego School of Medicine, will receive up to approximately $8.3 million over seven years from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

21 Apr 2017

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Biogen today announced the Committee for Medicinal Products for Human Use of the European Medicines Agency adopted a positive opinion recommending the granting of a marketing authorization for SPINRAZA to treat patients with spinal muscular atrophy (SMA).

21 Apr 2017

Hockey players with multiple concussions may have other injuries in their brains, research reveals

The relationship between head injuries suffered during contact sport and Alzheimer's disease is now being called into question thanks to research by the Sahlgrenska Academy, which has revealed that hockey players with multiple concussions probably have other injuries in their brains.

21 Apr 2017

MGH researchers provide direct link between ‘leaky gut’ and chronic inflammatory disease

With the help of genetically engineered mice, scientists at the Massachusetts General Hospital are moving closer to establishing the role that increased intestinal permeability, sometimes called a "leaky gut," plays in chronic inflammatory conditions.

20 Apr 2017

Study paves way to develop noninvasive diagnostic test for colorectal cancer

The type of bacteria in your gut may help diagnose colorectal cancer. Researchers at Baylor College of Medicine and other institutions have identified specific types of bacteria that seem to be abundant in individuals with colorectal cancer.

19 Apr 2017

Addressing unmet needs in prostate cancer

Prostate cancer is the second most diagnosed cancer globally with over a million men diagnosed worldwide. We are fortunate in that better diagnostic techniques and better awareness means that men are often being diagnosed earlier, which gives them a better chance of being cured.

19 Apr 2017

UTHealth researchers identify less invasive way to screen for colorectal cancer

Specific strains of bacteria in the gut are significantly associated with colorectal cancer, according to a new study by researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.

18 Apr 2017

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Cocaine, nicotine, capsaicin. These are just three familiar examples of the hundreds of thousands of small molecules (also called specialized or secondary metabolites) that plants use as chemical ammunition to protect themselves from predation.

17 Apr 2017

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

A vaccine targeting cytomegalovirus (CMV) antigen pp65, combined with high-dose chemotherapy (temozolomide), improved both progression-free survival and overall survival for a small group of glioblastoma (GBM) patients.

17 Apr 2017

Clemson University researcher receives NIH grant to advance study into abdominal aortic aneurysms

One of the top ten killers for men older than 55 is the target of Clemson University research that could lead to a new life-saving therapy and a better way of telling whether surgery is necessary.

12 Apr 2017

TSRI study could lead to personalized treatments for alcohol dependence

A new study led by scientists at The Scripps Research Institute could help researchers develop personalized treatments for alcoholism and alcohol use disorder.

12 Apr 2017

Gut microbes cause age-associated inflammation and premature death, mice study shows

Gut microbes cause age-associated inflammation and premature death in mice, McMaster University researchers have found. The study could lead to new strategies to improve intestinal health and immune function in older adults.

12 Apr 2017

NIH study provides unprecedented detail on host response to Ebola virus disease

Analysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health (NIH) in 2015 found changes in antiviral and immune response genes that pinpointed key transition points in the response to infection.

12 Apr 2017

NIH scientists identify protein complexes involved in promoting HSV infection and reactivation

Herpes simplex virus (HSV) infections last a lifetime. Once a person has been infected, the virus can remain dormant (latent) for years before periodically reactivating to cause recurrent disease. This poorly understood cycle has frustrated scientists for years.

12 Apr 2017

'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

More than 1,800 individuals carrying loss-of-function mutations in both copies of their genes, so-called "human knockouts," are described in the first major study to be published in Nature this week by an international collaboration led by the Perelman School of Medicine at the University of Pennsylvania and colleagues.

12 Apr 2017

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Zika virus is a mosquito-borne infectious disease linked to certain birth defects in infants in South and Central America and the United States.

11 Apr 2017

Research finding could offer new way to fight deadly pancreatic cancer

Pancreatic cancer, most frequently pancreatic ductal adenocarcinoma (PDAC), is the most lethal and aggressive of all cancers. Unfortunately, there are not many effective therapies available other than surgery, and that is not an option for many patients.

10 Apr 2017

Study compares insulin pump therapy and injections in type 1 diabetes patients during Ramadan fasting

A new study examining the risk of fasting during Ramadan for people with type 1 diabetes compared blood glucose control and the rates of hypoglycemia and hyperglycemia between users of insulin pump therapy versus multiple daily insulin injections.

7 Apr 2017

Therapeutics News and Research

Researchers discover cancer-fighting properties in beta blockers

New report suggests innovative approaches for better response to chemical inhalation disasters

UC San Diego Amazonian Center to receive NIH funding for malaria research

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Hockey players with multiple concussions may have other injuries in their brains, research reveals

MGH researchers provide direct link between ‘leaky gut’ and chronic inflammatory disease

Study paves way to develop noninvasive diagnostic test for colorectal cancer

Addressing unmet needs in prostate cancer

UTHealth researchers identify less invasive way to screen for colorectal cancer

Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

Clemson University researcher receives NIH grant to advance study into abdominal aortic aneurysms

TSRI study could lead to personalized treatments for alcohol dependence

Gut microbes cause age-associated inflammation and premature death, mice study shows

NIH study provides unprecedented detail on host response to Ebola virus disease

NIH scientists identify protein complexes involved in promoting HSV infection and reactivation

'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Research finding could offer new way to fight deadly pancreatic cancer

Study compares insulin pump therapy and injections in type 1 diabetes patients during Ramadan fasting

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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