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Spatial configuration of the genome is not inherited, but set up during embryogenesis

The architecture of the DNA-protein complexes that make up the genome in each cell nucleus regulates the course of early embryonic development.

23 May 2019

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

York University scientists have uncovered a unique set of genes that play a role in muscle cellular gene expression and differentiation which could lead to new therapeutic targets to prevent the spread of muscle cancer.

23 May 2019

Large study links rare DNA alterations to type 2 diabetes

An international consortium of scientists has analyzed protein-coding genes from nearly 46,000 people, linking rare DNA alterations to type 2 diabetes.

23 May 2019

Genetic variation in heart valve cells of developing fetus creates mitral valve prolapse

Genetic variation in heart valve cells of the developing fetus create the blueprint for the later development of mitral valve prolapse, according to the cover story of today's Science Translational Medicine.

23 May 2019

Researchers identify new anti-aging compounds among FDA-approved drugs

Researchers from Gero, Skolkovo Institute of Science and Technology, Moscow Institute of Physics and Technology, and University of Arkansas for Medical Sciences collaborated to derive a transcriptomic signature of aging, which they confirmed using large transcriptomic databases.

23 May 2019

Scientists develop new genetic tool to modify and understand gene function

Scientists of the National Center for Cardiovascular Research led by Rui Benedito have developed a new genetic tool (iSuRe-Cre) that provides certainty in Cre-inducible genetic modifications, a key technique for understanding gene function.

22 May 2019

Yeast species thrives, despite losing DNA repair genes years ago

Researchers have discovered an ancient species of budding yeast that has lost dozens of DNA repair genes, without any adverse effects.

22 May 2019

Researchers decode how molecular escorts help prevent cancer

The anti-tumor protein p53 can decide on the life or death of a cell: If it detects damage in the cell's genome, the protein pushes the cell to suicide.

22 May 2019

Scientists create bacteria with man-made DNA

In a landmark research study, a living organism (E. coli) has been made using entirely human-made DNA.

21 May 2019

Study explores why people at risk for Huntington's disease choose not to undergo genetic testing

As many as 90 percent of individuals who have a parent with Huntington's disease (HD) choose not to take a gene test that reveals if they will also develop the fatal disorder -- and a new study details the reasons why.

17 May 2019

Common bacterial pathogen of diarrhea diseases unknown to many people

Overall though, people are not as concerned as they were in the last survey in summer 2018.

17 May 2019

Researchers identify first gene that predisposes to fainting

Fainting is not solely caused by external factors. Your genes also play a part. This has recently been documented by research team from the University of Copenhagen, Statens Serum Institut and Rigshospitalet.

16 May 2019

CRISPR uncovers which gene fusions are critical for growth of cancer cells

In the first large-scale analysis of cancer gene fusions, which result from the merging of two previously separate genes, researchers at the Wellcome Sanger Institute, EMBL-EBI, Open Targets, GSK and their collaborators have used CRISPR to uncover which gene fusions are critical for the growth of cancer cells.

16 May 2019

Genome News and Research

Spatial configuration of the genome is not inherited, but set up during embryogenesis

Scientists uncover unique set of genes that play a role in muscle cellular gene regulation

Large study links rare DNA alterations to type 2 diabetes

Genetic variation in heart valve cells of developing fetus creates mitral valve prolapse

Researchers identify new anti-aging compounds among FDA-approved drugs

Scientists develop new genetic tool to modify and understand gene function

Yeast species thrives, despite losing DNA repair genes years ago

Researchers decode how molecular escorts help prevent cancer

Scientists create bacteria with man-made DNA

Study explores why people at risk for Huntington's disease choose not to undergo genetic testing

Common bacterial pathogen of diarrhea diseases unknown to many people

Researchers identify first gene that predisposes to fainting

CRISPR uncovers which gene fusions are critical for growth of cancer cells

Big data helps determine better research models to fight the spread of breast cancer

Researchers use cutting-edge technology to read the dark heart of chromosomes

New book examines circuitous history behind the investigation of cancer as contagious illness

Oxidative stress acts directly on telomeres to hasten cellular aging, study reveals

Harvard scientists uncover key mechanism that allows viruses to replicate

International team studies potential cancer suppression mechanisms in cetaceans

New recommendations on standards, ways to communicate quality of probiotics to end-users

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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