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COSMIC'S new 3D system can help identify and characterize cancer drug targets

COSMIC-3D, the most comprehensive system for exploring cancer mutations in three dimensions, is launched today by COSMIC, based at the Wellcome Trust Sanger Institute, in collaboration with Astex Pharmaceuticals, Cambridge, UK.

15 May 2017

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

Boosting a part of the immune system known to have anti-tumor properties may actually help tumors grow in cancers linked to chronic inflammation.

12 May 2017

Mayo Clinic research advances understanding of DNA repair mechanisms

We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.

12 May 2017

TUM scientists develop new pH sensor that provides insights into tumor metabolism

Tumors, inflammation and circulatory disorders locally disturb the body's acid-base balance. These changes in pH value could be used for example to verify the success of cancer treatments.

12 May 2017

Scientists use new RNA sequencing and statistical techniques to track stem cells in the nose

Adult stem cells have the ability to transform into many types of cells, but tracing the path individual stem cells follow as they mature and identifying the molecules that trigger these fateful decisions are difficult in a living animal.

12 May 2017

Discovery of key signals in the lungs and liver could pave way for immune disorder treatments

The discovery of key signals that help tissues repair after injury could pave the way for new treatments for asthma and organ scarring, a study suggests.

12 May 2017

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

The low oxygen concentrations that prevail in many tumors enhance their propensity to metastasize to other tissues. Researchers at Ludwig-Maximilians-Universitaet in Munich led by Professor Heiko Hermeking have now uncovered the molecular mechanism that links the two phenomena.

11 May 2017

Rat study reveals new treatment approach that could potentially prevent osteoarthritis

Maintaining the supply of a molecule that helps to nourish cartilage prevented osteoarthritis in animal models of the disease, according to a report published in Nature Communications online May 11.

11 May 2017

Chemical stimuli by small molecule can improve production of cartilage cells

Cell-based therapies could offer a way to treat cartilage injuries before the ultimate damage of osteoarthritis on articular cartilage.

11 May 2017

Gut microbiome may play key role in pathology of common cerebrovascular disease

Bacteria in the gut microbiome drive the formation of cerebral cavernous malformations (CCMs), clusters of dilated, thin-walled blood vessels in the brain that can cause stroke and seizures, according to new research published this week in Nature by researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 May 2017

New electrochemical method can remove extremely low levels of pollutants from water

When it comes to removing very dilute concentrations of pollutants from water, existing separation methods tend to be energy- and chemical-intensive. Now, a new method developed at MIT could provide a selective alternative for removing even extremely low levels of unwanted compounds.

10 May 2017

New findings pinpoint key feature of rare childhood disease that could help fast-track diagnosis

Australian scientists have shown, for the first time, that a family of untethered proteins builds up in the cells of children with a rare and serious genetic condition, known as mevalonate kinase deficiency (MKD).

10 May 2017

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

A common treatment for asthma, which is the most prevalent chronic childhood disease, requires use of an inhaler. But a big problem with inhalers, used to deliver steroids and other drugs in an aerosol form, is that children often don't operate them properly.

10 May 2017

Contrary behavior by blood vessels in the brainstem is what keeps us breathing, research suggests

Certain blood vessels in the brainstem constrict when blood vessels elsewhere in the body would dilate. And that contrary behavior is what keeps us breathing, according to a new paper by UConn researchers published May 8 in eLife.

9 May 2017

Study: Brain injury can increase impulsivity problems in rats

New research from the University of British Columbia confirms for the first time that even mild brain injury can result in impulse control problems in rats.

8 May 2017

Study uncovers potential new therapeutic targets for HCV infections

An international study led by researchers at Monash University' Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

8 May 2017

Researchers pinpoint gene that plays crucial role in formation of neural tube defects

Researchers have identified a gene that plays a key role in the formation of neural tube defects, a problem commonly found in infants of pregnant women with diabetes.

5 May 2017

Researchers find new way to make influenza visible to the naked eye

Researchers at the University of Notre Dame have discovered a way to make influenza visible to the naked eye, according to a new study in the Journal of the American Chemical Society.

5 May 2017

Researchers identify biomarker that could predict disease severity in glaucoma patients

Glaucoma, a leading cause of blindness worldwide, most often is diagnosed during a routine eye exam. Over time, elevated pressure inside the eye damages the optic nerve, leading to vision loss. Unfortunately, there's no way to accurately predict which patients might lose vision most rapidly.

4 May 2017

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to demonstrate that this yeast had antibacterial properties against streptococcus bacteria.

4 May 2017

Molecule News and Research

COSMIC'S new 3D system can help identify and characterize cancer drug targets

Immunoreceptor promotes tumor growth in mouse models of liver cancer driven by inflammation

Mayo Clinic research advances understanding of DNA repair mechanisms

TUM scientists develop new pH sensor that provides insights into tumor metabolism

Scientists use new RNA sequencing and statistical techniques to track stem cells in the nose

Discovery of key signals in the lungs and liver could pave way for immune disorder treatments

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

Rat study reveals new treatment approach that could potentially prevent osteoarthritis

Chemical stimuli by small molecule can improve production of cartilage cells

Gut microbiome may play key role in pathology of common cerebrovascular disease

New electrochemical method can remove extremely low levels of pollutants from water

New findings pinpoint key feature of rare childhood disease that could help fast-track diagnosis

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

Contrary behavior by blood vessels in the brainstem is what keeps us breathing, research suggests

Study: Brain injury can increase impulsivity problems in rats

Study uncovers potential new therapeutic targets for HCV infections

Researchers pinpoint gene that plays crucial role in formation of neural tube defects

Researchers find new way to make influenza visible to the naked eye

Researchers identify biomarker that could predict disease severity in glaucoma patients

Synthetic biologists re-engineer yeast cells to manufacture antibiotic penicillin

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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