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High levels of memory killer cells correlate with better survival in melanoma patients

Our skin contains specialized long-lived killer cells that protect against intruders. Researchers at Karolinska Institutet in Sweden and the University of Copenhagen in Denmark have now identified how these cells are formed, and shown that high levels of memory killer cells in cancer tissue correlate with a better survival rate in people with melanoma.

2 Jun 2023

Is having a new child associated with increased antidepressant treatment in men?

Study determines whether recent fatherhood was associated with increased antidepressant treatment.

2 Jun 2023

"Sepsis sensors" with magnetic nanoparticles rapidly detect bacterial pathogens

In the case of blood poisoning, the bacteria in the blood must be identified as fast as possible so that a life-saving therapy can be started.

1 Jun 2023

Smoke alarm: France's high maternal smoking rates fuel prematurity and low birth weight

Research highlights the adverse effects of active and passive maternal smoking on low birth weight and preterm delivery rates. It emphasizes the importance of smoking cessation and tobacco control policies to improve maternal and child health outcomes.

1 Jun 2023

Eye drops to slow the progression of nearsightedness in kids could be on the horizon

The results of a new clinical trial suggest that the first drug therapy to slow the progression of nearsightedness in kids could be on the horizon.

1 Jun 2023

NCI launches new initiative to test new drug combinations that target specific tumor alterations

The National Cancer Institute (NCI) has launched a large precision medicine cancer initiative to test the effectiveness of treating adults and children with new drug combinations that target specific tumor alterations.

1 Jun 2023

"Deep sequencing" of the genome informs diagnoses and treatment of vascular anomalies

Researchers from Children's Hospital of Philadelphia (CHOP) recently discovered that extremely thorough "deep sequencing" of the genome in tissue samples and cell-free DNA of patients with potentially life-threatening vascular anomalies captured several genetic variants related to disease that were not captured with conventional genetic sequencing methods.

1 Jun 2023

New data guides treatment choices for patients with r/r lymphoma during pregnancy

Today, Blood Advances published a study revealing that patients with relapsed/refractory (r/r) lymphoma during pregnancy experienced a progression-free survival rate of 24% and an overall survival rate of 83%.

1 Jun 2023

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Researchers reported on the treatment of rifampin-resistant tuberculosis in the United States using the FDA approved bedaquiline, pretomanid, and linezolid (BPaL) therapy.

1 Jun 2023

Pilot study reveals effective approach to boost adherence to Mediterranean ketogenic diet for memory concerns in older adults

Researchers explored strategies for enhancing compliance with a Mediterranean ketogenic nutrition program among older individuals.

1 Jun 2023

Special issue aims to deepen the conversation around cerebral palsy

Although cerebral palsy (CP) is the most common childhood-onset disability, there are very few evidence-based clinical practice guidelines or recommendations on how to treat and manage this condition.

31 May 2023

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) occurs in 30% of hospitalized cirrhosis patients, leading to over one million deaths worldwide each year.

31 May 2023

Scientists develop new immuno-therapeutic approach to target brain metastatic melanomas

Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models.

31 May 2023

New insights into how axons grow could lead to effective therapies for blindness, paralysis

Injuries to the nerves can blind or paralyze because adult nerve cells don't regenerate their connections. Now, a team of UConn School of Medicine researchers report in Development that at least a small population of nerve cells exist in everyone that could be coaxed to regrow, potentially restoring sight and movement.

31 May 2023

Cellular Origins Launches Constellation, its Configurable Robotic Platform to Enable Scalable Manufacture of Advanced Therapies

A closed, fully automated, and configurable robotic platform for cell therapy manufacture can achieve 30-fold increase in space efficiency and reduces production costs and labor by 51% and 16-fold, respectively.

From Cellular Origins 31 May 2023

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Melatonin, a hormone derived from the pineal gland, has diverse effects on cellular processes. This review explores its potential role as an epigenetic regulator, particularly in modulating DNA methylation, and suggests its use in combination therapy as a novel anticancer strategy.

30 May 2023

Experimental decoy provides long-term protection from SARS-Cov-2 infection

An experimental "decoy" provided long-term protection from infection by the pandemic virus in mice, a new study finds.

30 May 2023

Ultraflexible nanoelectrodes improve the efficacy of brain stimulation

Conventional implantable medical devices designed for brain stimulation are often too rigid and bulky for what is one of the body's softest and most delicate tissues.

30 May 2023

New method may help identify the essential ingredients for making an effective HIV vaccine

Since it was identified in 1984 as the cause of Acquired Immune Deficiency Syndrome (AIDS), the human immunodeficiency virus (HIV) has infected more than 80 million people and been responsible for some 40 million deaths worldwide, according to the World Health Organization (WHO).

30 May 2023

ENDO 2023 news conferences to highlight latest research in diabetes, obesity, reproductive health

Researchers will delve into the latest research in diabetes, obesity, reproductive health and other aspects of endocrinology during the Endocrine Society's ENDO 2023 news conferences June 15-18.

30 May 2023

Therapy News and Research

High levels of memory killer cells correlate with better survival in melanoma patients

Is having a new child associated with increased antidepressant treatment in men?

"Sepsis sensors" with magnetic nanoparticles rapidly detect bacterial pathogens

Smoke alarm: France's high maternal smoking rates fuel prematurity and low birth weight

Eye drops to slow the progression of nearsightedness in kids could be on the horizon

NCI launches new initiative to test new drug combinations that target specific tumor alterations

"Deep sequencing" of the genome informs diagnoses and treatment of vascular anomalies

New data guides treatment choices for patients with r/r lymphoma during pregnancy

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Pilot study reveals effective approach to boost adherence to Mediterranean ketogenic diet for memory concerns in older adults

Special issue aims to deepen the conversation around cerebral palsy

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

Scientists develop new immuno-therapeutic approach to target brain metastatic melanomas

New insights into how axons grow could lead to effective therapies for blindness, paralysis

Cellular Origins Launches Constellation, its Configurable Robotic Platform to Enable Scalable Manufacture of Advanced Therapies

Unlocking the potential of melatonin: A promising epigenetic weapon against cancer

Experimental decoy provides long-term protection from SARS-Cov-2 infection

Ultraflexible nanoelectrodes improve the efficacy of brain stimulation

New method may help identify the essential ingredients for making an effective HIV vaccine

ENDO 2023 news conferences to highlight latest research in diabetes, obesity, reproductive health

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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