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Two new subtypes of HPV+ head and neck cancers identified

Cases of human papillomavirus (HPV)-associated cancers of the head and neck, known as head and neck squamous cell carcinoma (HNSCC), are rapidly increasing throughout the United States.

31 Jul 2023

Tiny amounts of hydrogen sulfide could help people live healthier for longer

Future therapies to help people live healthy lives for longer could be developed from drugs that release tiny amounts of the gas hydrogen sulfide (H2S), new research has indicated.

31 Jul 2023

Early antiplatelet medication linked to improved stroke recovery

Administering antiplatelet medication within 24 hours of mechanical thrombectomy, an effective procedure for stroke, may help patients more successfully recover and prevent high-risk individuals from experiencing additional strokes, according to a study presented today at the Society of NeuroInterventional Surgery's (SNIS) 20th Annual Meeting.

31 Jul 2023

Newly identified protein plays a key role in the action of emerging anticancer therapies

Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers.

31 Jul 2023

Scrambler therapy: A new non-invasive treatment for chronic pain

A new review paper co-authored by two Johns Hopkins pain experts suggests that scrambler therapy, a noninvasive pain treatment, can yield significant relief for approximately 80%–90% of patients with chronic pain, and it may be more effective than another noninvasive therapy: transcutaneous electrical nerve stimulation (TENS).

31 Jul 2023

Researchers investigate the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma

Researchers investigated the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma.

31 Jul 2023

University Hospitals receives multiple stroke care awards

University Hospitals (UH) has received numerous American Heart Association/American Stroke Association Get With The Guidelines - Stroke achievement awards for demonstrating commitment to following the latest, research-based guidelines for the treatment of stroke, ultimately leading to more lives saved, shorter recovery times and fewer readmissions to the hospital.

28 Jul 2023

RNF41 protein could be a new therapeutic target against cirrhosis and liver inflammation

The RNF41 protein could be a new therapeutic target in the fight against two chronic liver diseases: cirrhosis and liver inflammation.

28 Jul 2023

Reinforcement learning improves performance of AI-based skin cancer diagnosis

Artificial intelligence (AI) is already being used to diagnose skin cancer, but it cannot (yet) keep pace with the complex decision-making of doctors in practice.

28 Jul 2023

Enhanced light sensitivity may worsen Alzheimer's symptoms

New Alzheimer’s research from UVA Health suggests that enhanced light sensitivity may contribute to “sundowning” – the worsening of symptoms late in the day – and spur sleep disruptions thought to contribute to the disease’s progression.

28 Jul 2023

New class of antibody could benefit patients with treatment-resistant cancers

A Cancer Research UK-funded clinical trial has shown, for the first time, that a new class of antibody could benefit cancer patients whose existing treatments have stopped working.

28 Jul 2023

Researchers seek to understand the Achilles' heel of insulin pump technology

Since the insulin pump started widespread use in the early 1980s, it's become the option of choice for type 1 diabetes patients to manage their glucose levels in a way that doesn't require testing their blood sugar and injecting insulin multiple times daily.

27 Jul 2023

New gene therapy shows promise in reversing chronic pain

Researchers at NYU College of Dentistry's Pain Research Center have developed a gene therapy that treats chronic pain by indirectly regulating a specific sodium ion channel, according to a new study published in the Proceedings of the National Academy of Sciences.

27 Jul 2023

Two new compounds can block cancer cell’s escape route

Cancer cells are capable of escaping chemotherapy and radiotherapy by activating a signaling pathway that prevents them from dying.

27 Jul 2023

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

A gene encoding a protein linked to tau production - tripartite motif protein 11 (TRIM11) - was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

Tails on engineered T cells could help fight cancer

In a promising form of immunotherapy known as CAR T-cell (chimeric antigen receptor) therapy, the patient's T cells are engineered to better recognize and attack antigens on the surface of cancer cells.

27 Jul 2023

Transcription factors may drive development of different colorectal cancer subtypes

New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors — proteins that help turn specific genes on or off by binding to nearby DNA — may play a central role in the degree of DNA methylation across the genome, contributing to the development of different subtypes of these cancers.

27 Jul 2023

Study finds that patients with systemic autoimmune rheumatic diseases had a lower antibody response than healthy controls after Omicron infection

Study investigated if patients with systemic autoimmune rheumatic diseases (SARDs) have a reduced immunological response.

27 Jul 2023

COVID-19 treatment: study evaluates ACEi and ARB effects on clinical outcomes

A group of researchers compared the effects of angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers.

27 Jul 2023

Therapy News and Research

Two new subtypes of HPV+ head and neck cancers identified

Tiny amounts of hydrogen sulfide could help people live healthier for longer

Early antiplatelet medication linked to improved stroke recovery

Newly identified protein plays a key role in the action of emerging anticancer therapies

Scrambler therapy: A new non-invasive treatment for chronic pain

Researchers investigate the efficacy of a novel intra-tumoral drug delivery carrier in treating oral squamous cell carcinoma

University Hospitals receives multiple stroke care awards

RNF41 protein could be a new therapeutic target against cirrhosis and liver inflammation

Reinforcement learning improves performance of AI-based skin cancer diagnosis

Enhanced light sensitivity may worsen Alzheimer's symptoms

New class of antibody could benefit patients with treatment-resistant cancers

Researchers seek to understand the Achilles' heel of insulin pump technology

New gene therapy shows promise in reversing chronic pain

Two new compounds can block cancer cell’s escape route

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

New gene editing approach could revolutionize the treatment of blood disorders

Tails on engineered T cells could help fight cancer

Transcription factors may drive development of different colorectal cancer subtypes

Study finds that patients with systemic autoimmune rheumatic diseases had a lower antibody response than healthy controls after Omicron infection

COVID-19 treatment: study evaluates ACEi and ARB effects on clinical outcomes

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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