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p38 MAPK drives epigenetic activation of fibrotic genes in lung fibroblasts

A new research paper was published in Volume 18 of Aging-US on March 3, 2026, titled "P38 MAPK is involved in epigenetic regulation of fibrotic genes in replication induced senescence in lung fibroblasts."

10 Mar 2026

Integrated laser chip could bring biosensor diagnostics to patients’ homes

A research team at Chalmers University of Technology, Sweden, has developed new laser technology that could lead to tiny, cost-effective biosensors.

10 Mar 2026

How somatic mutations shape disease and reveal new drug targets

Researchers reviewed how somatic mutations accumulate in normal and diseased tissues, showing that natural selection can expand clones that influence disease risk, tissue adaptation, or cellular resilience. The study proposes somatic genomics as a powerful strategy to uncover disease mechanisms and identify new therapeutic targets across multiple conditions.

8 Mar 2026

Studies highlight benefits of osseointegration for patients with limb amputations

Three new studies from Hospital for Special Surgery (HSS) highlight the use and advantages of osseointegration (OI) for individuals with an amputation, in some instances challenging prevailing beliefs about which patients would benefit.

6 Mar 2026

BCAT2 enzyme identified as a target for diabetic foot recovery

Diabetic macrovascular complications are the main cause of death and disability in diabetes patients, of which vascular calcification is one of the key pathological mechanisms. Calcification in atherosclerotic plaque can cause stiffness and decreased compliance of the vascular wall, and induce atherosclerotic plaque rupture, which increases the risk of acute cardiovascular events.

6 Mar 2026

MIMETAS publishes breakthrough study on 3D blood-brain barrier model with unidirectional flow

Scientists at MIMETAS have published a new study describing a scalable, self-assembling human blood-brain barrier (BBB) model that combines physiological relevance with high-throughput capability.

5 Mar 2026

Study finds most sustainable diet indices overlook industrial food processing

A scoping review of 57 studies found that most tools used to assess sustainable diets focus on food production and consumption while largely ignoring food processing and other stages of the food system. The findings suggest that overlooking ultra-processed foods and processing impacts may lead to incomplete sustainability assessments and highlight the need for more comprehensive evaluation frameworks.

4 Mar 2026

New method isolates true transcription factor targets in tuberculosis bacteria

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.

2 Mar 2026

Brain organoids show goal-directed learning in control task

Imagine balancing a ruler vertically in the palm of your hand: you have to constantly pay attention to the angle of the ruler and make many small adjustments to make sure it doesn't fall over. It takes practice to get good at this.

19 Feb 2026

Gut microbiome may shape response to GLP-1 drugs, new review suggests

This review examines how GLP-1 receptor agonists and the gut microbiome influence one another through bile acid signaling, short-chain fatty acids, and inflammatory pathways. It explores how microbial composition may shape treatment response and highlights the need for controlled human studies to enable microbiome-informed precision therapy.

19 Feb 2026

Vascularized liver tissueoid-on-a-chip recreates tissue regeneration and transplant rejection

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a vascularized liver tissueoid-on-a-chip (LToC) platform that recapitulates key structural, functional, and immunological features of human liver tissue, enabling the study of liver regeneration and immune-mediated allograft rejection in a physiologically relevant human system.

18 Feb 2026

Why lung cancer in never smokers is rising and how targeted detection could reduce deaths

Lung cancer in never smokers is an increasingly recognized global health issue with distinct biological drivers, environmental risk factors, and genetic susceptibilities. Improved risk modelling, targeted screening strategies, and preventive approaches are needed to enable earlier detection and reduce mortality in this growing patient group.

15 Feb 2026

Clinics sour on CMS after agency scraps 10-year primary care program only months in

On a 15-degree morning in January, a clinic in the Appalachian Mountains of North Carolina began to fill up with patients.

13 Feb 2026

Rising lung cancer in never smokers demands urgent research focus

Lung cancer patients who have never smoked make up a significant and growing share of global lung cancer cases, yet remain an understudied group, according to a new review written by UCL (University College London) researchers.

12 Feb 2026

SCAI applauds bipartisan law removing barriers to pediatric specialty care

The Society for Cardiovascular Angiography and Interventions (SCAI) applauds the enactment of the Accelerating Kids' Access to Care Act. This bipartisan law removes longstanding administrative barriers that have delayed access to out-of-state specialty care for children with complex or congenital medical conditions.

6 Feb 2026

Revvity unveils new high-impact discovery platforms and showcases recent innovations at SLAS2026

Revvity, Inc. announced the launch of multiple new discovery platforms and technologies at SLAS2026, which are designed to accelerate high-throughput drug discovery workflows.

5 Feb 2026

Poison at play: Unsafe levels of lead found in half of New Orleans playgrounds

Sarah Hess started taking her toddler, Josie, to Mickey Markey Playground in 2010 because she thought it would offer a refuge from lead.

5 Feb 2026

Ride Cincinnati grant funds research on immune activating wafer for glioblastoma treatment

A multidisciplinary team of University of Cincinnati Cancer Center researchers has received a $40,000 Ride Cincinnati grant to study a delayed release preparation, or wafer, of an immunostimulatory molecule to stimulate the central nervous system (CNS) immune system after surgery to remove glioblastoma, a form of primary brain cancer.

3 Feb 2026

Engineered liver tissue model mimics early metabolic liver disease

More than 100 million people in the United States suffer from metabolic dysfunction-associated steatotic liver disease (MASLD), characterized by a buildup of fat in the liver.