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The power of organoids in speeding up lifesaving drug development

Organoids are miniature tissue or organ models formed by stem cells (including pluripotent stem cells, tissue-specific adult stem cells, etc.) or progenitor cells in an in vitro three-dimensional culture system, which possess structural features and partial functions analogous to their corresponding in vivo organs. In 2009, the Hans Clevers laboratory developed the first intestinal organoid, marking the inception of organoid-based disease modeling.

8 May 2026

New ‘heart-on-a-chip’ to halt cardiac damage caused by Duchenne

Duchenne Parent Project Spain (DPPE) has launched the BEAT Project, a research initiative focused on one of the key challenges associated with Duchenne and Becker muscular dystrophies: progressive heart damage. Cardiomyopathy is the leading cause of death in patients with DMD.

7 May 2026

GADD45B promotes apoptosis in intestinal injury through DNA demethylation

Intestinal ischemia/reperfusion (I/R) injury is a common pathophysiological phenomenon that is widely present in various primary intestinal diseases and systemic critical illnesses, potentially leading to multiple organ dysfunction and failure, with high morbidity and mortality.

5 May 2026

New technique uses electronic jolt and nanoparticles to reveal early signs of pancreatic cancer

Scientists at Oregon Health & Science University have developed a new technique using an electronic jolt and nanoparticles to reveal the telltale signal of an insidious form of cancer.

4 May 2026

New genomic study tracks rare blood disease in children

Aplastic anemia is a rare, life-threatening blood disorder where patients are unable to make enough blood cells due to the immune system's attack on blood stem cells. The condition can progress to myelodysplastic syndrome (MDS) and leukemia. A study led by scientists at St. Jude Children's Research Hospital, with multiple collaborating institutions, used state-of-the-art genomic techniques to profile 619 children and adults with aplastic anemia.

4 May 2026

New tools for quicker and easier Mpox diagnosis

Following the rise in monkeypox (Mpox) cases, particularly in countries where the disease had not traditionally been observed, the World Health Organization (WHO) declared a Public Health Emergency of International Concern in June 2022 and again in August 2024.

4 May 2026

AI and CRISPR technologies drive proactive health monitoring

JMIR Publications today featured two new stories in its News and Perspectives section, highlighting a shift toward proactive, tech-integrated health monitoring.

30 Apr 2026

New cytometer measures cell stiffness to improve disease diagnosis

Researchers from Brown University and their collaborators have developed a new way to measure the properties of cells - an important development, they say, because accurate measurements of changes in cell elasticity can be used to better understand diseases, diagnose patient symptoms and provide more accurate prognoses.

25 Apr 2026

Newborns carry antibiotic resistance genes within first hours of life

Antibiotic resistance genes (ARGs) – segments of DNA that help bacteria survive the effects of antibiotics – can be present in newborns within the first hours of life, according to research presented at ESCMID Global 2026.

20 Apr 2026

New microfluidic device improves tumor cell enrichment from pleural effusions

Pleural effusion cytology is already used in cancer diagnosis, especially in metastatic settings, but its sensitivity can be limited.

20 Apr 2026

New imager separates UV and infrared light to find cancerous nodes

Researchers have developed a compact camera that captures ultraviolet, near-infrared and visible images using a single chip. Inspired by the multiwavelength vision capability of the mantis shrimp, the camera could help surgeons identify lymph nodes connected to a tumor and assess whether cancer has spread to them, making cancer surgery safer and less invasive.

17 Apr 2026

New biochip detects tiny genetic markers in 20 minutes

A team of scientists from Nanyang Technological University, Singapore (NTU Singapore) has developed a new biochip that, when paired with Artificial Intelligence (AI), can detect quickly and accurately extremely small amounts of microRNAs, which are tiny genetic markers linked to diseases such as heart disease.

15 Apr 2026

Medi-Cal immigrant enrollment is dropping. Researchers point to Trump’s policies.

For months, a cloud of fear has hovered over the immigrant community in San Bernardino, California, making it hard for María González to do her job as a community health worker in this city where almost a quarter of residents are foreign-born.

15 Apr 2026

How next-generation proteomics is decoding the language of life

This review examines how next-generation protein sequencing and analysis technologies are expanding proteomics beyond the limits of mass spectrometry, especially for detecting proteoforms and analyzing proteins at single-molecule resolution. It highlights maturing fluorescence-based and nanopore-based platforms that could complement existing methods and deepen insight into protein sequence, structure, function, and modification states.

13 Apr 2026

Experts call for expanded Medicaid coverage to improve children’s health

As states reassess Medicaid coverage following recent federal policy changes and the end of pandemic-era protections, researchers are advocating for evidence-based health care policy reform and expanded Medicaid coverage for children.

9 Apr 2026

Organ-on-chip model advances study of sexually transmitted infections

Sexually transmitted infections (STIs) not only impact an individual's health but also result in multibillion-dollar economic losses worldwide.

3 Apr 2026

Left-ventricular unloading during angioplasty fails to improve patient outcomes

The first randomized trial to compare standard percutaneous coronary intervention (PCI), also known as coronary angioplasty, with PCI accompanied by the use of a temporary, miniaturized pump to support the heart in patients with both severe coronary heart disease and moderate to severe heart failure found no significant difference between the two approaches.

29 Mar 2026

HOBIT device improves oxygen supply for drug-producing cells

Implanting living cells as long-term drug producers could transform treatment for numerous diseases, but it is difficult to house the tiny workers in quantities high enough to ensure dosage needs are met while also keeping the cells alive and thriving.

27 Mar 2026

Novo Nordisk principal scientist highlights the urgency of advancing human-relevant 3D tissue models ahead of the 11th 3D Tissue Models Summit

As regulatory momentum accelerates globally to reduce reliance on animal testing, leading experts in microphysiological systems (MPS), complex in vitro models (CIVMs), organoids, and organ‑on‑chip technologies are preparing to gather at the 11th 3D Tissue Models Summit, taking place April 28–30, 2026 in Boston.

From Hanson Wade Group - 11th 3D Tissue Models Summit 2026 27 Mar 2026

Microfluidic chips enable realistic modeling of tumor immune environments

The challenge is that the tumor immune microenvironment is not a static backdrop but a constantly shifting ecosystem shaped by cancer cells, immune cells, stromal cells, cytokines, and physical barriers.

26 Mar 2026