Cholesterol News and Research

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Cholesterol is a waxy, fat-like substance made in the liver, and found in the blood and in all cells of the body. Cholesterol is important for good health and is needed for making cell walls, tissues, hormones, vitamin D, and bile acid.

Healthy lifestyle cuts hearing impairment risk by 14%, metabolism is key driver

Hearing impairment ranks as the third largest contributor to global disability among sensory disorders, with prevalence rising across younger and middle-aged populations alongside older adults.

12 Aug 2026

Researchers tracked biological aging for decades and found a striking pattern in women

Accelerated biological age in midlife was associated with higher risks of cardiovascular disease and death in both men and women over nearly three decades of follow-up. Women with accelerated biological age also showed a higher risk of dementia, although adding biological age to standard risk factors provided only minimal additional predictive value.

12 Aug 2026

Why pulses could play a bigger role in healthy and sustainable diets

A narrative review finds that pulses may support gut and metabolic health through their fiber, protein, phytochemicals, and interactions with the gut microbiota, while offering a lower environmental footprint than many animal protein sources. Human evidence is strongest for selected cardiometabolic outcomes, while many microbiome and fermentation-related benefits remain supported mainly by animal and laboratory studies.

9 Aug 2026

Genetic analysis of 1 million people points to FNIP1 as a promising metabolic target

Mega-scale exome sequencing of 1,032,116 people identified 59 independent genes linked to the TG:HDL ratio, including 44 rare-coding associations not detected in the previous largest analysis. Ultra-rare FNIP1 loss-of-function variants were associated with favorable fat distribution, lower liver fat and glycemia, and around 60% lower odds of a composite cardiometabolic disease outcome.

7 Aug 2026

New study explores cholesterol-driven survival mechanisms in pancreatic cancer

A University of Oklahoma researcher has received a five-year, $2 million grant from the National Cancer Institute to investigate how pancreatic cancer uses cholesterol to survive chemotherapy.

6 Aug 2026

HMGCR emerges as a promising target for precision cancer therapies

A growing body of evidence is reshaping how scientists and clinicians understand the role of cancer metabolism, placing the enzyme HMGCR at the center of a rapidly evolving therapeutic landscape.

5 Aug 2026

Tadalafil may increase glaucoma risk in men with enlarged prostates

An erectile dysfunction drug that is also used to treat symptoms like sudden urgency and frequency, which are associated with an enlarged prostate in men, may heighten the risk of the serious eye condition, glaucoma, finds a large comparative study published online in the British Journal of Ophthalmology.

4 Aug 2026

New study advances understanding of dementia after age 90

It may seem natural to assume that people experience cognitive decline after age 90, but until recently, researchers had limited evidence about how advanced age affects the brain.

4 Aug 2026

Exercise helps protect Hispanic adults from late life cognitive decline

Previous studies have examined the associations between adherence to LS7 and cognitive outcomes, with findings suggesting that higher LS7 scores are associated with better cognitive performance, reduced dementia risk and improved brain health.

4 Aug 2026

Blood filtration method helps clear circulating lipids and toxic microplastics

The machine is not new. Some version of it has run in hospital treatment rooms for about four decades, drawing blood from one arm, separating out the plasma, passing it across a filter or an adsorber, and returning it to the other arm.

4 Aug 2026

Perilla oil may curb platelet reactivity and inflammatory signaling in smokers

An eight-week randomized trial found that daily perilla oil increased plasma and red-cell ALA, plasma EPA, and platelet closure time in healthy smokers. Perilla oil also reduced TNF-α and TBX21 gene expression, but it did not improve broader coagulation, lipid, endothelial, or postprandial markers.

3 Aug 2026

Texas A&M study links polyethylene microplastics to fatty liver disease

Microplastics have become nearly impossible to avoid. They have been detected in oceans, drinking water and even the human body, but scientists are still uncovering how they affect human health.

3 Aug 2026

Microbial metabolites could help improve functional cure rates for hepatitis B

Chronic hepatitis B (CHB) remains a major global challenge. Current therapies suppress HBV but rarely achieve functional cure (sustained HBsAg loss).

30 Jul 2026

Study links dietary fructose to aggressive spread of ovarian cancer

A new study from The Wistar Institute has uncovered an unexpected link between fructose - a common dietary sugar - and the spread of an aggressive form of ovarian cancer.

30 Jul 2026

Researchers train AI to detect diabetes and assign four diagnostic labels

Researchers developed a two-stage machine learning framework that detected diabetes and classified records as prediabetes, type 1, type 2, or type 3c diabetes using two public datasets. XGBoost showed strong internal performance, but inconsistent model rankings, non-standard variables, and the absence of external clinical validation limit immediate use.

29 Jul 2026

Heatwave exposure associated with accelerated biological aging in middle-aged and older adults

As global climate change intensifies, heatwaves are becoming more frequent, longer, and more severe, emerging as an important environmental stressor for human health.

28 Jul 2026

Review finds blueberry and grape polyphenols may improve vascular health

A review of 37 publications found that grape- and blueberry-derived polyphenols were associated with modest improvements in cardiovascular risk markers, particularly endothelial function. However, most studies were small or short-term, frequently tested concentrated products, and measured biomarkers rather than cardiovascular events.

27 Jul 2026