Electrophysiology News and Research

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Major gaps found in cholesterol management for young adults

Fewer than half of young adults with severely high low-density lipoprotein (LDL-C), or "bad" cholesterol, levels start taking a statin within five years of first high LDL-C measurement, according to a study published in JACC, the flagship journal of the American College of Cardiology, and presented at the American Heart Association's 2025 Scientific Sessions.

6 Nov 2025

AI-driven ECG improves detection of severe heart attacks

Using artificial intelligence (AI) to analyze electrocardiograms (ECG) improved detection of severe heart attacks, including those that presented with unconventional symptoms, or atypical ECG patterns, and reduced false positives, according to a study published in JACC: Cardiovascular Interventions and simultaneously presented at TCT 2025 in San Francisco.

29 Oct 2025

Novel AI ECG model outperforms standard triage for acute coronary occlusion

29 Oct 2025

Emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder

In a peer-reviewed article published today in Brain Medicine, a European research team presents a focused review of emerging neuromodulation techniques for treatment-resistant obsessive-compulsive disorder (OCD).

28 Oct 2025

New insight into TRPM3 heat sensor reveals how the body detects temperature

The ability to sense heat protects the body from burns and injury. But how the body actually feels temperature has remained an elusive mystery.

24 Oct 2025

Abstinence or limiting alcohol intake may lead to clinically meaningful blood pressure reductions

Light-to-moderate alcohol consumption is associated with increases in blood pressure (BP) and stopping drinking – even drinking less – may lead to clinically meaningful BP reductions, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

22 Oct 2025

Unusual heart rhythm disorder common in people with long COVID

A new study from Karolinska Institutet shows that an unusual heart rhythm disorder, POTS, is particularly common in people with long COVID. The majority of those affected are middle-aged women.

3 Oct 2025

New ACC Scientific Statement highlights inflammation in cardiovascular disease

The American College of Cardiology (ACC) released today its second Scientific Statement, Inflammation and Cardiovascular Disease (CVD).

29 Sep 2025

Scientists map step-by-step activation of brain receptors

When it comes to brain proteins, small changes can make a dramatic difference. Researchers studying NMDA (N-methyl-D-aspartate) receptors, which are essential for learning, memory and moment-by-moment consciousness, know that even slight changes in their activity level can mean the difference between normal function and serious neurological disorders.

24 Sep 2025

Study reveals how a key spinal circuit shapes the choreography of sex

For decades, it was thought that while the brain orchestrated male sexual behaviour – arousal, courtship, and copulation – the spinal cord merely executed the final act: ejaculation.

23 Sep 2025

Lab-grown mini brains reveal neural misfires linked to schizophrenia and bipolar disorder

Pea-sized brains grown in a lab have for the first time revealed the unique way neurons might misfire due to schizophrenia and bipolar disorder, psychiatric ailments that affect millions of people worldwide but are difficult to diagnose because of the lack of understanding of their molecular basis.

22 Sep 2025

New research links postictal symptoms in epilepsy to hidden brain waves

In everyday clinical practice, symptoms are regularly observed after epileptic seizures, known as "post-ictal symptoms", which, in contrast to the usually short duration of seizures, typically last several minutes to hours. Besides symptoms such as impaired speech and language comprehension, a state of disorientation may occur.

19 Sep 2025

Researchers identify seizure-associated depolarization as cause of post-ictal symptoms

People with temporal lobe epilepsy in particular often wander around aimlessly and unconsciously after a seizure. Researchers at the University Hospital Bonn (UKB), the University of Bonn, and the German Center for Neurodegenerative Diseases (DZNE) have identified a neurobiological mechanism that could be responsible for this so-called post-ictal wandering and potentially other postictal symptoms.

18 Sep 2025

Axxam and B'SYS partner to expand access to validated ion channel cell lines for high-throughput electrophysiology

Axxam S.p.A., a premier provider of integrated early drug discovery services, and B'SYS GmbH, a specialist in ion channel biology, are pleased to announce a strategic collaboration focused on enabling access to validated ion channel cell lines for hit and lead identification through high-throughput electrophysiological screening.

From Axxam S.p.A 8 Sep 2025

Artificial intelligence offers individualized anticoagulation decisions for atrial fibrillation

Mount Sinai researchers developed an AI model to make individualized treatment recommendations for atrial fibrillation (AF) patients-helping clinicians accurately decide whether or not to treat them with anticoagulants (blood thinner medications) to prevent stroke, which is currently the standard treatment course in this patient population.

1 Sep 2025

$New hypothesis links internal fat biology to heart failure with preserved ejection fraction$

New hypothesis links internal fat biology to heart failure with preserved ejection fraction

Heart failure with preserved ejection fraction (HFpEF) appears to develop as a result of changes in the biology of a person's internal fat tissue, according to the Adipokine Hypothesis, a new way of understanding how fat may impact the heart.

1 Sep 2025

Daily use of low-dose colchicine may slow growth of blood mutations linked to disease

Taking low-dose colchicine daily may slow the progression of a common acquired gene mutation found in the blood of older adults that can lead to certain blood cancers and increased risk of cardiovascular disease, according to a subanalysis of the LoDoCo2 trial published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at ESC Congress 2025.

29 Aug 2025

Fentanyl abuse impairs cardiac cell function and contributes to heart rhythm defects

In recent years, fentanyl, a synthetic opioid that is 50 to 100 times stronger than morphine, has been a main contributor to the opioid crisis.

28 Aug 2025

New guidelines highlight importance of vaccination for heart patients

The American College of Cardiology has issued Concise Clinical Guidance (CCG) recommending vaccines to protect adults with heart disease against respiratory illness, including influenza, COVID-19 and RSV, and other diseases where vaccination is shown to offer cardiovascular protective benefits.

26 Aug 2025

Unlocking neuroglia’s potential to halt neurodegeneration and restore brain homeostasis

In a revealing Genomic Press Interview published today in Brain Medicine, Professor Alexei Verkhratsky dismantles decades of neuroscience orthodoxy with discoveries that position neuroglia as active architects of brain function rather than passive cellular bystanders.