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Spring fatigue is a cultural rather than biological phenomenon

When the days start to get longer again, Dr Christine Blume's phone rings more often. That's because journalists want to ask the sleep researcher what spring fatigue is all about.

9 Mar 2026

Ketone body can strengthen the fitness and antitumor activity of CAR T cells

A naturally occurring byproduct of liver metabolism–the ketone body, β-hydroxybutyrate (BHB)–can strengthen the fitness and antitumor activity of CAR T cells.

6 Mar 2026

Scientists identify ANKIB1 as key regulator of innate immune signaling

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or viral intruders.

6 Mar 2026

Researchers identify TRIM13 protein as key driver of immune suppression in sepsis

Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction.

4 Mar 2026

Exercise during chemotherapy boosts breast cancer patients' quality of life

For many women with breast cancer, the very treatment that saves their lives can also bring fatigue, loss of muscle mass, emotional strain and other daunting obstacles.

26 Feb 2026

No evidence connects tick bites to chronic health problems

When researchers studied Norwegians who thought tick bites caused their chronic health problems, they found no objective evidence linking the symptoms to ticks.

25 Feb 2026

Moments of awe show measurable links to reduced loneliness in daily life

Daily diary data from healthcare workers and community adults during COVID lockdowns showed that people reported less loneliness on days when they experienced greater awe. This association was partly explained by increased feelings of connectedness to nature, although the observational design prevents causal conclusions.

23 Feb 2026

Delirium after cardiac procedures carries serious long-term risks

Delirium is a sudden onset of acute confusion in which those affected are disoriented, have impaired attention, and experience altered perception -often accompanied by hallucinations or sleep disturbances.

20 Feb 2026

Remote-controlled CAR T cells offer safer cancer therapy

Among the most promising tools of cancer therapy, engineered immune cells known as chimeric antigen-receptor (CAR) T cells have already transformed the treatment of blood cancers.

19 Feb 2026

Lifestyle medicine practice linked to lower clinician burnout

Healthcare professionals report that treating patients with lifestyle medicine helps to reduce burnout by increasing professional satisfaction, meaning, and a sense of effectiveness at work, according to a new study published in BMC Health Services Research.

18 Feb 2026

Preoperative combination treatment shows promise for some patients with pancreatic cancer

A new UCLA investigator-initiated study sponsored by the UCLA Health Jonsson Comprehensive Cancer Center has found that adding immunotherapy to standard chemotherapy before surgery is safe and shows promise for some patients with borderline-resectable pancreatic cancer, a disease that has historically been difficult to treat.

17 Feb 2026

Chronic inflammation shapes cancer progression and immunotherapy response

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

16 Feb 2026

SLAMF6 discovery offers hope for non-responding cancer patients

Cancer researchers working on immunotherapies have made a big discovery: SLAMF6, a molecule on the surface of immune cells that prevents T cells from effectively attacking tumors – and, in mice, they've found a way to neutralize it.

12 Feb 2026

IVF study finds shorter insemination protects embryo availability without harming success

Short-term sperm–oocyte co-incubation during IVF cycles with only one or two retrieved oocytes produced cumulative live birth rates comparable to conventional overnight insemination. It also improved fertilisation metrics and reduced cancellation or no-embryo cycles, suggesting practical laboratory advantages without improving overall live birth probability.

4 Feb 2026

Immune dysfunction persists after combined TB and HIV therapy

The immune system remains seriously out-of-whack – in an inflammatory state of overactivation and impaired functionality – following the international gold standard for treating people with latent tuberculosis (TB) and HIV, a team at Texas Biomedical Research Institute reports in Nature Communications.

14 Jan 2026

New research identifies faulty TRPM3 ion channel in ME/CFS immune cells

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), providing long-awaited validation for hundreds of thousands of Australians living with the debilitating illness.

13 Jan 2026

Spleen-driven immune tolerance may protect transplanted organs

New research from the University of Minnesota Medical School offers a new view of how the immune system responds to organ transplants.

7 Jan 2026

Endurance athletes experience significant training challenges during menopause

A new study finds menopause symptoms to be very frequently reported by female endurance athletes, with many perceiving a negative effect on their training and performance.

18 Dec 2025

Combined physical frailty and depression may sharply raise dementia risk

Concurrent physical frailty and depression likely boost the risk of dementia in older people, with the interaction of these 2 factors alone contributing around 17% of the overall risk, suggest the findings of a large international study, published in the open access journal General Psychiatry.

16 Dec 2025

Gut bacteria mimicry can accelerate the progression of multiple sclerosis

If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system.

15 Dec 2025