Fibrosis News and Research

RSS

Fibrosis is the growth of fibrous tissue.

Study reveals unexpected mechanism driving extreme antibiotic resistance

A patient with a severe infection is prescribed a potent antibiotic. Hopes for improvement are high, but just after treatment is given, resistance to the drug increases thousands of times. How could this happen?

23 Jul 2026

Emerging PPAR therapies offer new hope for primary biliary cholangitis

Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Although a first-line treatment exists, 40% of patients do not respond adequately to it or cannot tolerate it, so new treatment options need to be developed.

23 Jul 2026

AI platform uncovers promising target for chronic pain treatmen

Despite the widespread availability of analgesics, pain management remains one of the most significant and pervasive challenges in modern medicine, with more than 20% of the global population suffering from chronic pain, especially chronic neuropathic pain characterized by central sensitization.

22 Jul 2026

Study tests chronotype’s liver link and finds no significant association

Researchers found no significant association between chronotype and FibroScan-derived liver fat or stiffness in 119 medication-naïve adults with overweight or obesity. The exploratory findings cannot exclude smaller effects, particularly for fibrosis, and require confirmation in larger longitudinal studies.

21 Jul 2026

Vitamin D falls short as an add-on treatment for endometriosis

An eight-week randomized trial of 66 women found that adjunctive vitamin D did not significantly or meaningfully improve endometriosis pain or quality of life compared with placebo during dienogest therapy. The results do not support routine short-term adjunctive supplementation, although the brief trial and absence of post-treatment vitamin D measurements leave longer-term effects uncertain.

19 Jul 2026

NOX4 inhibition may protect hearts affected by Duchenne muscular dystrophy

Researchers at the University of South Florida USF Health Morsani College of Medicine have identified a potential pathway that could protect cardiac function in people with Duchenne muscular dystrophy, a progressive and fatal genetic disease that weakens the body's muscles.

17 Jul 2026

Computational framework identifies synergistic compound pairs in herbal medicines

Herbal medicines have long been used in disease treatment, often through formulas that combine multiple herbs to enhance therapeutic effects and reduce side effects.

16 Jul 2026

Discovery of lung protein offers hope for pulmonary fibrosis

Pulmonary fibrosis is a deadly disease where scar tissue grows in the lungs, making breathing more difficult. Approximately 2,170 Australians are diagnosed annually with idiopathic pulmonary fibrosis (IPF), a form of the disease with no known cause and very few treatments.

16 Jul 2026

Patient-derived organoids uncover new targets for chronic pancreatitis treatment

Around three million people worldwide struggle with chronic pancreatitis, a condition wherein the pancreas becomes inflamed, scarred, and painful.

14 Jul 2026

Insilico and Bora Pharmaceuticals forge strategic AI-driven drug discovery alliance

Insilico Medicine, a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, today announced a multi-target strategic alliance with Bora Pharmaceuticals Co., Ltd., a global leader in pharmaceutical manufacturing.

14 Jul 2026

Ultrasensitive biosensor detects early-stage liver fibrosis using small amount of blood

A research team led by Professor Jinsung Park of the Department of Biomechatronic Engineering at Sungkyunkwan University(SKKU), working jointly with Professor Pil-Soo Sung of the College of Medicine at the Catholic University of Korea and Professor Si-Hyun Bae, President of Eunpyeong St. Mary's Hospital, has developed an ultrasensitive electrochemical biosensor capable of accurately detecting "early-stage liver fibrosis"—a condition in which the liver progressively hardens—using only a small amount of blood.

14 Jul 2026

Harvard University hosts the world's largest conference dedicated to longevity biotechnology

The 13th Aging Research & Drug Discovery (ARDD) Meeting, the world's largest conference dedicated to longevity biotechnology, will take place from October 1-3, 2026, at the David Rubenstein Treehouse at Harvard University.

11 Jul 2026

Study links oxalate to systemic inflammation and heart damage

Oxalic acid might do more than just contribute to the formation of kidney stones — it may also be an underappreciated driver of inflammation and heart damage in people with impaired kidney function.

11 Jul 2026

Insilico Medicine founder to highlight sustainable longevity at BIO Asia-Taiwan

Dr. Alex Zhavoronkov, Founder and CEO of Insilico Medicine, has been invited to attend BIO Asia-Taiwan, which will be held from July 15 to 19 in Taiwan, China.

11 Jul 2026

Review highlights macrophages as key drivers of chronic transplant rejection

A comprehensive review led by Professors Malgorzata Kloc and Xian Chang Li at the Immunobiology and Transplant Science Center of Houston Methodist Hospital in the United States was published in Volume 2, article number 29 of the journal Immunity & Inflammation on June 30, 2026.

9 Jul 2026

GLP-1 drugs may reduce lung scarring from Long COVID in diabetic patients

GLP-1 agonists have become popular treatments for weight loss and type 2 diabetes, and newer studies suggest other health benefits as well.

9 Jul 2026

Molecular changes in the liver of space travelers provide clues about aging

What happens to the human body in space may help scientists create new anti-aging therapies.

7 Jul 2026

Insilico Medicine highlights AI drug discovery progress at executive summit

Dr. Alex Aliper, Co-founder and President of Insilico Medicine, will attend the AI for Good Global Summit 2026 in Geneva, Switzerland, on July 7.

3 Jul 2026

New testing approach improves pulmonary fibrosis diagnosis and treatment

A new Mayo Clinic study shows that integrating telomere length evaluation and genetic testing into pulmonary care can significantly change how physicians diagnose and treat pulmonary fibrosis - in some cases even redirecting the course of care.

2 Jul 2026

Insilico Medicine partners with Takeda for AI-driven drug discovery

Insilico Medicine, a leader in clinical-stage generative AI for drug discovery, today announced a strategic collaboration agreement with Takeda to use its proprietary end-to-end platform, Pharma.AI, to advance drug candidates across the company's therapeutic areas.

2 Jul 2026