Frontotemporal Dementia News and Research

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Both low and moderate-high intensity exercise could help fight against Alzheimer's

Researchers at University of California San Diego and Wake Forest University have found that both low and moderate-high intensity exercise could be valuable tools in the fight against Alzheimer's.

24 Apr 2025

New approach may prevent neurotoxic protein aggregates in ALS

Researchers at Goethe University, Johannes Gutenberg University Mainz and Kiel University discover possible method for preventing protein aggregates – Cluster4Future PROXIDRUGS research project.

23 Apr 2025

Emotional empathy may be preserved in people with Alzheimer's disease

People with Alzheimer's disease may retain their ability to empathize, despite declines in other social abilities, finds a new study led by University College London (UCL) researchers.

23 Apr 2025

Scientists develop lab model to study TDP-43 accumulation in neurodegeneration

Accumulation of a protein called TDP-43 is a key feature of ALS and frontotemporal dementia. In a newly published study, researchers report 'seeding' this accumulation through fragments of the culprit protein created in the lab.

28 Mar 2025

Advanced imaging technique reveals how nuclear pores regulate molecular movement

Just as cities must carefully manage the flow of cars in and out of downtown, cells regulate the movement of molecules into and out of the nucleus.

22 Mar 2025

Deep sleep may protect against neurodegeneration

Sleep disturbances may accelerate neurodegeneration, but whether they cause or result from disease remains unclear. Improving sleep quality could help protect against cognitive decline and brain aging.

20 Mar 2025

New scientific clue could unlock key cellular pathway leading to neurodegenerative diseases

In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key cellular pathway leading to devastating neurodegenerative diseases like Alzheimer's disease, and the progressive damage to the brain's frontal and temporal lobes in frontotemporal degeneration (FTD) and the associated disease amyotrophic lateral sclerosis (ALS).

14 Mar 2025

New approach to tau protein clearance offers hope for Alzheimer's treatment

USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human “mini-brains,” known as organoids.

5 Mar 2025

Stress granules as potential biomarkers for neurodegenerative diseases

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

3 Mar 2025

Blood test for Alzheimer’s could replace costly and invasive spinal taps

Researchers indicate that the Lumipulse p-tau217 assay may reduce over 50% of lumbar punctures performed for diagnosing Alzheimer's disease.

20 Feb 2025

Study sheds light on diagnostic challenges in frontotemporal dementia

University of Queensland researchers discovered that nearly 70 per cent of suspected frontotemporal dementia patients ultimately did not have the disease, in a study aimed at identifying factors that contribute to misdiagnosis of this notoriously difficult to diagnose disorder.

10 Feb 2025

Dementia risk impacts family planning decisions

Living in a family where there is genetic risk for dementia significantly affects choices about having children and how to parent, finds a new study led by UCL researchers.

15 Jan 2025

Genetic risk for dementia shapes parenting and family planning choices

Living in a family where there is genetic risk for dementia significantly affects choices about having children and how to parent, finds a new study led by UCL researchers.

13 Jan 2025

Promising ultrasound therapy for Alzheimer's disease licensed to new start-up

A promising ultrasound therapy to potentially restore brain function in people with Alzheimer's disease has been licenced to a new start-up spun out of The University of Queensland.

16 Dec 2024

New funding for innovative dementia vaccine research

Alzheimer's disease and frontotemporal dementia are devastating disorders that emerge following the buildup of misfolded proteins in the brain.

13 Dec 2024

Frontotemporal dementia disrupts empathy for pain, study reveals

Study reveals diminished brain activity related to empathy for pain in individuals with behavioral variant frontotemporal dementia (bvFTD), using task-based fMRI. Findings show a stark reduction in neural responses tied to affective empathy, highlighting early bvFTD impacts on social cognition.

5 Dec 2024

Loss of empathy in frontotemporal dementia linked to brain activity changes

Patients with frontotemporal dementia often lack the ability to empathize. A study at Karolinska Institutet has now shown that these patients do not show the same brain activity as healthy individuals when they witness the pain of others, a finding that it is hoped will increase understanding of this specific dementia disease.

3 Dec 2024

Traditional Chinese herb shows promise against Alzheimer’s and Parkinson’s

Zizyphi spinosi semen demonstrates neuroprotective effects, improving cognitive function and reducing amyloid and tau pathology in models of aging and dementia.

8 Nov 2024

C-Path announces important leadership appointments in neurology and Alzheimer's research

Critical Path Institute (C-Path) today announced key leadership appointments: Diane Stephenson, Ph.D., has been promoted to Vice President of Neurology, and Nadine Tatton, Ph.D., has been welcomed as the new Executive Director of C-Path's Critical Path for Alzheimer's Disease (CPAD) Consortium.

7 Nov 2024

Ancient herb shows promise in fighting dementia

Attempts to discover a breakthrough dementia drug might be drawing attention these days, but traditional medicinal products can offer hints for preventive medicine.

6 Nov 2024