Genome News and Research

RSS

Major global alliance invests billions to build predictive AI models of biology

Biohub, the U.S. Department of Energy, the National Institutes of Health, and new funding partners today announced a major expansion of an international effort to generate and make accessible the data enabling predictive AI models of biology.

7 Oct 2026

Skin biopsy offers less invasive diagnosis for mitochondrial disease

Researchers at Children's Hospital Colorado (Children's Colorado) and the University of Colorado Anschutz School of Medicine have published one of the largest studies to date evaluating advanced laboratory testing for mitochondrial disease, providing new evidence that a small skin biopsy can often help diagnose these rare and complex conditions without the need for more invasive procedures.

6 Oct 2026

Phase III trial tests MRD-guided treatment for patients with ER-positive/HER2-negative breast cancer

Alliance Foundation Trials, LLC (AFT), a national leader in conducting innovative, practice-changing cancer clinical trials, and Natera, Inc., a global leader in cell-free DNA and precision medicine, today announced the launch of AFT-70 NAVIGATE, a randomized phase III trial evaluating a novel molecular residual disease (MRD)-guided treatment strategy for patients with intermediate and high-risk ER-positive/HER2-negative early breast cancer.

5 Oct 2026

New workflow rapidly identifies deadly fungal bloodstream infections

Bloodstream infections are a persistent threat to hospitalized patients, and those caused by fungi are particularly dangerous. Candida species are responsible for most invasive fungal infections worldwide and rank among the leading causes of hospital-acquired bloodstream infections overall.

5 Oct 2026

Cambridge and London Life Sciences Showcase returns during JPM Healthcare Week 2027

o2h co-discovery has announced that the Cambridge × London Life Sciences Showcase will return for its second edition during J.P. Morgan Healthcare Week 2027 in San Francisco.

From o2h Group 5 Oct 2026

Dana-Farber research reveals possible new target for treatment of sickle cell and beta thalassemia

That pathway involves BACH2 and NRF2 and was discovered using a large genome-wide association study that enabled an analysis of genes related to fetal hemoglobin from a wide range of ancestries, including European, African, and Asian ancestries.

5 Oct 2026

Could the gut be priming the body for a more severe stroke?

Gut bacteria may prime immune cells to worsen stroke damage

2 Oct 2026

New project explores mitochondrial evolution across diverse life forms

A research consortium has generated the broadest look yet at the proteins that make up mitochondria, capturing the organelle's diversity across multiple branches on the tree of complex life.

1 Oct 2026

Varying mutation rates in healthy organs explain cancer risk

A new study by scientists at City of Hope® and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in organs of healthy individuals.

1 Oct 2026

Streamlining CRISPR workflows, from editing to analysis

INTEGRA's automated solutions optimize CRISPR workflows, enhancing gene editing efficiency and accelerating the path to innovative therapeutic developments.

From INTEGRA Biosciences 30 Sep 2026

What older adults do on screens may matter more than total screen time

Across 8,996 older adults in four cohorts, television viewing was associated with poorer global cognition, while computer use was associated with better cognitive performance, with the strongest positive associations at low-to-moderate levels of use. Mendelian randomization supported these opposing patterns and linked genetically predicted television viewing time to lower left insula volume, which accounted for an estimated 14.8% of its association with poorer cognitive performance.

29 Sep 2026

Bile DNA sequencing helps identify hidden pancreatobiliary tumors

Distinguishing malignant from benign biliary strictures remains a major clinical challenge. Endoscopic retrograde cholangiopancreatography (ERCP)-guided cytology and biopsy may be inconclusive, particularly in early-stage disease or when tissue is scarce.

29 Sep 2026

An approved Ebola antibody may miss its mark against Bundibugyo virus

Researchers analyzed 44 Bundibugyo virus genomes and modeled how approved and experimental Ebola antibodies might bind the virus’s glycoprotein. The models predicted disrupted binding for Ebanga, conserved targets for MBP134, and different binding behavior for the complete Inmazeb cocktail than for two of its antibodies alone; laboratory tests are needed to determine whether these findings translate into treatment benefit.

28 Sep 2026

Intentional substance exposures at school rise sharply among younger children

A new study found that rates of intentional substance exposures at school reported to U.S. poison centers increased substantially among elementary- and middle-school-aged children from 2000 through 2024, while high-school-aged adolescents continued to experience the highest rates of serious medical outcomes and hospital admissions.

28 Sep 2026

Cancer cells erase sections of Y chromosome to trigger tumor growth in men

A new study found that cancer cells selectively chip away gene-rich sections of the Y chromosome, triggering ripples that regulate tumor growth.

28 Sep 2026

New tool to mutate phages boosts the fight against superbugs

A new tool to mutate bacteriophages – viruses that infect bacteria – provides a "big leap" forward in both our understanding of how they function, and our ability to harness their full potential.

25 Sep 2026

Researchers find secret protein that drives cancer cell division

A previously unknown protein, hidden in RNA thought not to encode proteins, helps cells divide correctly. The RNA molecule that encodes the protein also has a function of its own in cell division.

25 Sep 2026

Five research teams secure funding for frontotemporal dementia studies

The Kissick Family Foundation, in partnership with the Milken Institute Science Philanthropy's Accelerator for Research and Collaboration (SPARC), today announced five research teams selected to receive a total of $2.5 million through the third funding cycle of the Kissick Family Foundation Frontotemporal Dementia (FTD) Grant Program.

24 Sep 2026

A child's gut microbiome may offer early clues to type 1 diabetes risk

Researchers tracking 887 children at high genetic risk of type 1 diabetes identified three distinct patterns of gut microbiome maturation during early childhood. One pattern was associated with substantially higher risk of islet autoantibody seroconversion or type 1 diabetes, while host genetic background altered the risk associated with another pattern.

23 Sep 2026

Cancer-related DNA changes may appear in blood years before diagnosis

Researchers found that genome-wide plasma cfDNA methylation profiles collected before diagnosis contained early molecular signatures associated with future prostate and breast cancer, with prostate silencer methylation providing the stronger risk stratification. Breast enhancer signals were weaker and varied by subtype and disease stage, indicating that cfDNA methylation may have greater value for risk assessment and surveillance than as a standalone diagnostic test.

23 Sep 2026