Green Fluorescent Protein (GFP) News and Research

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Study shows SARS-CoV-2 infection induces global alterations of the host endomembrane system

Researchers observed that Golgi fragmentation induced by SARS-CoV-2 facilitates viral trafficking.

11 Mar 2022

Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

Researchers elucidated antiviral activities of aminoglycoside geneticin against seven SARS-CoV-2 variants using different cell lines and respiratory tissues.

11 Mar 2022

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

A recent study posted to the bioRxiv* pre-print server investigated the ability of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to inhibit the human immune response against viral infection.

15 Feb 2022

Mutational analysis of SARS-CoV-2 main protease

A new study discussed the findings of a comprehensive mutational analysis of the main protease (Mpro) of SARS-CoV-2.

1 Feb 2022

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

A study recently identified Neurolipin-1 or NRP1, a host factor for SARS-CoV-2 infection, as a cargo retrograde-transported by the ESCPE-1.

26 Jan 2022

SARS-CoV-2 virus co-opts intrinsic cellular machinery to suppress interferon production

In a recent study posted to the bioRxiv* preprint server, researchers evaluated the mechanism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-associated inflammatory marker interferon (IFN) repression in hosts.

25 Jan 2022

SARS-CoV-2 shown to spread through cell-to-cell transmission

A new study investigated SARS-CoV-2 cell-to-cell transmission in the context of cell-free infection and compared it to SARS-CoV.

10 Jan 2022

Study suggests spike mutation makes SARS-CoV-2 Omicron milder

The Omicron spike is relatively poorly cleaved and impaired in mediating cell-cell fusion and syncytia formation, contrary to predictions.

28 Dec 2021

Molecular mechanism of SARS-Cov-2-induced thrombosis

Researchers demonstrate that the exposure of platelets to the SARS-CoV-2 spike protein promotes their activation and adhesion.

21 Dec 2021

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

A new study demonstrates lethal infection of the olfactory epithelium in a mouse model that could help understand the mechanisms of COVID-19.

12 Dec 2021

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

A novel mechanism by which SARS-CoV-2 inhibits the innate immune response; that is, ORF10 induces mitophagy-mediated MAVS degradation by binding to NIX.

5 Dec 2021

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Researchers recently conducted a study to identify host factors affecting cellular interactions of the SARS-CoV-2 spike protein.

16 Nov 2021

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes.

29 Oct 2021

Study finds FDA-approved drug has potent antiviral activity against SARS-CoV-2 and variants of concern

A new study aimed to examine the antiviral potential of atovaquone against the original SARS-CoV-2 strain and other variants of concern.

25 Oct 2021

Study sheds light on neurologic symptoms caused by SARS-CoV-2 infection

Researchers in Australia and Finland have provided important insights into how infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – might affect nervous system circuitries and cause neurologic symptoms.

6 Sep 2021

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

The common analogy for CRISPR gene editing is that it works like molecular scissors, cutting out select sections of DNA. Stanley Qi, assistant professor of bioengineering at Stanford University, likes that analogy, but he thinks it's time to reimagine CRISPR as a Swiss Army knife.

4 Sep 2021

Green Fluorescent Protein (GFP) News and Research

Study shows SARS-CoV-2 infection induces global alterations of the host endomembrane system

Aminoglycoside antibiotic geneticin shows selective antiviral effect against SARS-CoV-2

SARS-CoV-2 ORF6 inhibits mRNA export to favour viral translation and suppress innate signalling

Mutational analysis of SARS-CoV-2 main protease

Endosomal sorting of neuropilin-1 in SARS-CoV-2 infectivity

SARS-CoV-2 virus co-opts intrinsic cellular machinery to suppress interferon production

SARS-CoV-2 shown to spread through cell-to-cell transmission

Study suggests spike mutation makes SARS-CoV-2 Omicron milder

Molecular mechanism of SARS-Cov-2-induced thrombosis

Nasal infection drives lethal lung injury due to SARS-CoV-2 in mice

SARS-CoV-2 ORF10 degrades mitochondrial antiviral signaling protein to suppress immune response

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

Study finds FDA-approved drug has potent antiviral activity against SARS-CoV-2 and variants of concern

Study sheds light on neurologic symptoms caused by SARS-CoV-2 infection

Stanford researchers engineer an efficient, multi-purpose, mini CRISPR system

Nasal version of AstraZeneca SARS-CoV-2 vaccine prevents infection in animal models

Could novel biosensors facilitate SARS-CoV-2 antiviral drug research?

The technology behind face masks that can diagnose COVID-19

Modified Vaccinia Ankara model vaccine prevents COVID-19 in transgenic mice study

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