Head and Neck Cancer News and Research

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Head and Neck Cancer is cancer that arises in the head or neck region (in the nasal cavity, sinuses, lips, mouth, salivary glands, throat, or larynx [voice box]).

Pre and post-surgical immunotherapy improves survival in head and neck cancer patients

Patients with locally advanced head and neck cancer who received the immune checkpoint inhibitor pembrolizumab before, during and after standard-of-care surgery had longer event-free survival without the cancer coming back and higher rates of substantial tumor shrinkage prior to surgery, according to the first interim analysis of a randomized, open-label phase 3 clinical trial led by investigators from Dana-Farber Brigham Cancer Center and Washington University School of Medicine in St. Louis.

27 Apr 2025

Dana-Farber experts present innovative cancer studies at the 2025 AACR Annual Meeting

Numerous studies conducted by researchers at Dana-Farber Cancer Institute report progress for cancers including head and neck cancer, metastatic breast cancer and lung cancer.

27 Apr 2025

Step-and-shoot proton arc therapy reduces cancer treatment side effects

For many cancer patients, side effects from radiation can be debilitating. But a new way of delivering radiation treatment has proven effective at eliminating a hard-to-treat cancer with the only side effect being light skin discoloration, even nine months after treatment.

24 Apr 2025

Expansion of mutant blood cells linked to worse cancer outcomes

Researchers from the Francis Crick Institute, UCL, Gustave Roussy and Memorial Sloan Kettering Cancer Center (MSK), have discovered that expansion of mutant blood cells, a phenomenon linked to aging, can be found in cancerous tumors, and this is associated with worse outcomes for patients.

23 Apr 2025

Study sheds new light on the mechanisms underlying head and neck cancer metastasis

A recent study published in Engineering has shed new light on the mechanisms underlying the metastasis of head and neck squamous cell carcinoma (HNSCC). The research identified enolase 2 (ENO2), a crucial glycolytic enzyme, as a significant factor associated with lymphatic metastasis in HNSCC.

27 Mar 2025

Citrus remedy squeezes out dry mouth for cancer patients

A natural citrus oil from oranges, lemons, and limes is proving highly effective in relieving dry mouth, and when combined with a new lipid formulation, new research suggests it may be effective without significant side effects.

24 Mar 2025

Caregivers of cancer patients face high rates of PTSD

Every year, millions of family members and friends provide care for loved ones undergoing cancer treatment, often at great emotional cost.

19 Mar 2025

Combination immunotherapy improves treatment response for head and neck cancer

Researchers conducting a clinical trial of immunotherapy drugs for people with head and neck squamous cell carcinomas (HNSCCs) found that patients responded better to a combination of two immunotherapies than patients who received just one immunotherapy drug.

13 Mar 2025

Walking more steps and exercise linked to lower risk of death in postmenopausal cancer survivors

Among postmenopausal women with a history of cancer, taking more daily steps and engaging in moderate-to-vigorous physical activity were both associated with a significantly reduced risk of death from cardiovascular disease, according to preliminary research presented at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2025.

10 Mar 2025

Novel treatment approach shows promise for advanced HPV-negative head and neck cancer

Researchers from the University of Chicago Medicine Comprehensive Cancer Center demonstrated the potential of a novel treatment approach including immunotherapy to treat advanced human papillomavirus (HPV)-negative head and neck squamous cell carcinoma (HNSCC).

7 Mar 2025

First-ever clinical trials evaluate fenofibrate as treatment for HPV-related cancers

A team from University Hospitals Seidman Cancer Center is launching the nation's first-ever clinical trials evaluating the cholesterol drug fenofibrate (Triglide, Fibricor, Lipofen) as an investigational and potential treatment for patients with HPV+ cervical and HPV+ head and neck cancer (HNSCC).

28 Feb 2025

New clinical trial seeks alternatives for head and neck cancer patients unable to use cisplatin

A physician-scientist at the University of Oklahoma is part of an international effort seeking new options for patients with head and neck cancer who cannot receive the standard chemotherapy drug cisplatin.

21 Feb 2025

Unlocking the potential of double negative memory B cells in cancer treatment

University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – known as the tertiary lymphoid structure – where they become frustratingly dysfunctional when in close contact with tumors.

19 Feb 2025

New procedure standard/practice guideline released for fibroblast activation protein PET

The Society of Nuclear Medicine and Molecular Imaging (SNMMI) and the European Association of Nuclear Medicine (EANM) have issued a new procedure standard/practice guideline for the use of fibroblast activation protein (FAP) PET.

25 Jan 2025

Coffee and tea consumption may protect against head and neck cancers

In a new analysis of data from more than a dozen studies, coffee and tea consumption was linked with lower risks of developing head and neck cancers, including cancers of the mouth and throat.

30 Dec 2024

Can drinking coffee or tea help prevent head and neck cancer?

In a recent analysis of data from more than a dozen studies, coffee and tea consumption was linked with lower risks of developing head and neck cancer, including cancers of the mouth and throat. The findings are published by Wiley online in CANCER, a peer-reviewed journal of the American Cancer Society.

24 Dec 2024

Coffee and tea consumption linked with lower risk of head and neck cancer

In a recent analysis of data from more than a dozen studies, coffee and tea consumption was linked with lower risks of developing head and neck cancer, including cancers of the mouth and throat.

23 Dec 2024

A new era of targeted therapy with antibody–drug conjugates

TBC

From Sino Biological Inc. 16 Dec 2024

New technique offers safer option for head and neck reconstruction

Sometimes, moving just a few inches can go a long way. Osaka Metropolitan University researchers have developed a promising technique for head and neck reconstruction that shifts the placement of transferred tissue with blood vessels attached, offering a safer, faster option for patients with complex tissue defects, especially those at high risk.

13 Dec 2024

Improving head and neck reconstruction with a modified pedicled flap

Osaka Metropolitan University researchers have developed a promising technique for head and neck reconstruction that shifts the placement of transferred tissue with blood vessels attached, offering a safer, faster option for patients with complex tissue defects, especially those at high risk.