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Decoding cerebellar neural patterns in movement disorders

The cerebellum is a region of the brain that helps us refine our movements and learn new motor skills.

3 Jul 2024

High-fat diet triggers anxiety in male rats through gut-brain axis disruption

Researchers investigate the impact of a high-fat diet on gut microbiome diversity and its effects on anxiety-related symptoms.

20 Jun 2024

Researchers investigate the gene-brain-behavior link in autism using generative machine learning

Researchers used 3D transport-based morphometry to visualize brain changes linked to 16p11.2 CNV, achieving high prediction accuracy and advancing autism precision medicine.

18 Jun 2024

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Researchers discovered a rare telomere mutation (TTAGGT) in a family, revealing that human telomeres can tolerate non-canonical sequences, impacting telomere maintenance and disease.

4 Jun 2024

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Researchers discovered that Plexin-B1 plays a crucial role in regulating peri-plaque glial nets in Alzheimer’s disease, potentially opening new avenues for treatment by targeting this protein.

29 May 2024

UNIGE's synthetic anticoagulant provides reliable alternative to heparin

Anticoagulant treatments are crucial for managing many conditions, such as heart disease, stroke and venous thrombosis.

30 Apr 2024

Study suggests lingering coronavirus in tissues may contribute to long COVID symptoms

Study investigated whether SARS-CoV-2 lingers in tissues after COVID-19 recovery and if it's linked to long COVID symptoms. They found viral RNA in various organs, and its presence correlated with long COVID symptoms.

25 Apr 2024

Research reveals potential target for enfortumab vedotin therapy in urothelial carcinoma

Under the leadership of PD Dr. Niklas Klümper, Assistant Physician at the Department of Urology at the University Hospital Bonn (UKB) and Clinician Scientist of the BMBF-funded ACCENT program and PD Dr. Markus Eckstein, senior physician at the Institute of Pathology at the Uniklinikum Erlangen of the Friedrich-Alexander-University Erlangen-Nürnberg (FAU), an interdisciplinary research team has published new findings that indicate which patients with advanced urothelial carcinoma could benefit in particular from the new targeted therapy with the antibody-drug conjugate enfortumab vedotin.

24 Apr 2024

Repurposed nasal antibiotic neomycin shows promise in preventing and treating respiratory viral infections

Intranasal administration of neomycin sulfate in murine models shows promise as a prophylactic and therapeutic agent against respiratory viruses like influenza A and SARS-CoV-2 by inducing interferon-stimulated gene (ISG) expression, independent of microbiota and interferon activation.

24 Apr 2024

Arabica coffee's genetic legacy unveiled

The key to growing coffee plants that can better resist climate change in the decades to come may lie in the ancient past.

15 Apr 2024

Maleic acid treatment enhances bacterial cellulose for bone tissue engineering

The field of bone tissue engineering (BTE) was a promising avenue for addressing bone injuries and defects by constructing artificial scaffolds with bionic functionalities.

15 Apr 2024

Study reveals how SARS-CoV-2 hijacks lung cells to drive COVID-19 severity

Researchers identified how SARS-CoV-2 targets and manipulates specific lung cells, using innovative techniques to trace the virus's impact on the cells' gene expression, revealing insights into early COVID-19 pathogenesis.

14 Apr 2024

New technique reveals insights into gut cell dynamics during inflammation

Cells within the intestines perform various roles including nutrient absorption, sensing, and maintaining homeostasis.

2 Apr 2024

Using whole genome sequencing to identify non-culturable Legionella

Legionnaires' disease (LD), a rare and severe type of pneumonia, is a respiratory infection caused by species of Legionella bacteria.

21 Mar 2024

Mapping the heart's cellular blueprint: New insights into cardiac structure and disease repair

Researchers unveil the complex cellular architecture of the heart using advanced RNA sequencing and imaging techniques, shedding light on the intricate organization of heart cells and their developmental pathways.

14 Mar 2024

Researchers discover diverse and spatially coordinated cardiac cells involved in heart development

Researchers use a combination of scRNA-seq and multiplexed error-robust fluorescence in situ hybridization to better understand cardiac cell types.

13 Mar 2024

Tracing Monkeypox virus: Leveraging ancient orangutan DNA to investigate the 1965 Rotterdam Zoo outbreak

Ancient DNA analysis of museum-preserved orangutan teeth reveals the cause of the 1965 zoo outbreak in the Netherlands as monkeypox virus (MPXV) infections, demonstrating the power of museomic techniques in tracing historic viral transmissions.

12 Mar 2024

Mapping the brain: How cell types and location influence Parkinson’s disease

A single-cell spatial transcriptome analysis on murine brain expression in age and disease using a Parkinson's disease.

27 Feb 2024

New approach to treating neuropathic pain offers the possibility of non-opioid pain relief for millions

Researchers investigated the selective activity of sigmoid 2 receptor (σ2R) or transmembrane protein 97 (TMEM97) ligands on murine neuropathic pain models, their effects on nociceptive neurons and the mechanism of action after 24 hours.

5 Feb 2024

The anti-cancer potential of sRNAs isolated from different mushroom species

Study reveals that sRNAs from certain mushrooms, particularly Boletus edulis and Agaricus bisporus, show promising anti-cancer properties, with varying efficacy across different species.

31 Jan 2024