Kidney Cancer News and Research

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Kidney cancer is usually defined is a cancer that originates in the kidney. The two most common types of kidney cancer, reflecting their location within the kidney, are renal cell carcinoma (RCC) and urothelial cell carcinoma (UCC) of the renal pelvis.

Non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma

A new study led by investigators from the UCLA Health Jonsson Comprehensive Cancer Center has demonstrated a new, non-invasive imaging technique can accurately detect clear-cell renal cell carcinoma, the most common form of kidney cancer.

3 Oct 2024

Excess body weight at first cancer diagnosis increases risk of second cancer

Adults with excess body weight at their first cancer diagnosis face a higher risk of developing a second primary cancer, particularly those related to obesity, according to a recent study. The research emphasizes the need for survivorship guidelines targeting weight management.

22 Sep 2024

Trial finds no benefit of adding nivolumab to tivozanib for advanced kidney cancer

In an international multicenter randomized phase 3 clinical trial led by Dana-Farber Cancer Institute, researchers tested the addition of the immune checkpoint inhibitor (ICI) nivolumab to treatment with tivozanib for patients with advanced clear cell renal cell carcinoma, a form of kidney cancer.

13 Sep 2024

Cancer cases in the US continued to be underdiagnosed during the second year of the COVID-19 pandemic

Researchers examine how the COVID-19 pandemic affected cancer diagnosis rates between 2021 and 2020.

13 Sep 2024

Belzutifan shows promise in treating advanced renal cell carcinoma

The LITESPARK-005 phase 3 clinical enrolled 746 patients with metastatic clear cell renal cell carcinoma (ccRCC) who had progressed after treatment with both an immune checkpoint inhibitor (ICI) and an anti-angiogenic therapy.

21 Aug 2024

METRNL protein identified as key player in cancer progression

A protein called Meteorin-like (METRNL) in the tumor microenvironment saps energy from T cells, thereby severely limiting their ability to fight cancer, according to new research directed by investigators at the Johns Hopkins University School of Medicine and the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy. Finding ways to block the effects of METRNL signaling on tumor-infiltrating T cells may allow these immune cells to regain the energy necessary to eliminate tumors.

7 Aug 2024

Combining radiation with chemotherapy enhances survival in oligometastatic pancreatic cancer

Researchers from The University of Texas MD Anderson Cancer Center demonstrated that adding metastasis-directed radiation therapy to standard-of-care chemotherapy improved progression-free survival (PFS) in patients with oligometastatic pancreatic cancer.

5 Aug 2024

UCLA investigators receive $800,000 grant to treat and prevent aggressive kidney cancer

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have received an $800,000 grant from the V Foundation to find new ways to treat and prevent a severe form of kidney cancer associated with a hereditary syndrome caused by mutations in the fumarate hydratase (FH) gene.

16 Jul 2024

GLP-1 drugs found to lower cancer risk in diabetes patients

Research finds that GLP-1 receptor agonists significantly reduce the risk of 10 out of 13 obesity-associated cancers in type 2 diabetes patients compared to insulins, but show varied results against metformin.

8 Jul 2024

Scientists map all the possible outcomes of changes to key tumor-suppressing gene

Researchers at the Francis Crick Institute have mapped all the possible outcomes of changes to a tumor-suppressing gene called VHL, the first step in a huge research endeavor to unpick the outcomes of tens of thousands of genetic variations in genes associated with cancer.

5 Jul 2024

Live biotherapeutic product can improve clinical outcomes for patients with kidney cancer

Physician scientists from City of Hope, one of the largest cancer research and treatment organizations in the United States, found that people with metastatic kidney cancer who orally took a live biotherapeutic product called CBM588 while in treatment with immunotherapy and enzymatic tyrosine kinase inhibitors experienced improved health outcomes.

28 Jun 2024

Research finds increased cancer risk in diabetic adults aged 40-54 years

Diabetes significantly increases the risk of cancer, particularly in people aged 40-54 years, new research shows.

26 Jun 2024

Breakthrough biomarker predicts recurrence risk in clear cell renal cancer

Researchers from the University of Michigan Health Rogel Cancer Center have discovered a biomarker that could help identify which renal cancer patients have a higher risk of recurrence.

25 Jun 2024

Expert orthopedic surgeon saves man’s leg from being amputated after damage from advanced cancer

Richard Monti, a father of six and a real estate developer on Long Island, thought that his metastatic kidney cancer diagnosis would be the toughest battle to endure in his life.

21 Jun 2024

New WHO classification of kidney tumors integrates molecular diagnostics

Renal tumor pathology has evolved considerably, expanding from two main types of renal malignant tumors to over 20 distinct types.

18 Jun 2024

Americans with HIV are living longer. Federal spending isn’t keeping up.

Malcolm Reid recently marked the anniversary of his HIV diagnosis on Facebook. "Diagnosed with HIV 28 years ago, AND TODAY I THRIVE," he wrote in a post in April, which garnered dozens of responses.

17 Jun 2024

Macrophages play an unexpected role in the complicated obesity-cancer connection

Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer, a Vanderbilt University Medical Center-led research team has discovered.

12 Jun 2024

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Advanced clear cell renal cell carcinoma (ccRCC) is a deadly form of kidney cancer with few treatment options; even with new immunotherapies, only around one in 10 patients ultimately survive.

4 Jun 2024

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

Vaccinia viruses are therapeutic tools with different biomedical applications depending on the susceptibility characteristics.

24 May 2024

Physician-pharmacy integration not associated with change in the care of cancer patients

Integration of pharmacies with physician practices, where on-site pharmacies open at physician practice locations, is a growing trend in cancer treatment.

23 May 2024