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Discovery offers a breakthrough approach to combat prostate tumor growth

Prostate cancer relies on genetic "switches", called enhancers, that can turn on tumor-promoting genes.

22 Oct 2025

Breakthrough in RNA-targeted drug discovery offers hope against viral diseases

In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus that causes COVID-19.

6 Oct 2025

New class of antibiotics shows potent activity against multidrug-resistant bacteria

Scientists at the University of Liverpool, working with international collaborators, have discovered Novltex, a groundbreaking new class of antibiotics with potent activity against some of the world's most dangerous multidrug-resistant (MDR) bacteria.

18 Sep 2025

Researchers receive new funding to advance promising therapy for multiple sclerosis

A Canadian-led international research team, spearheaded by Dr. Fang Liu at the Centre for Addiction and Mental Health (CAMH) has received nearly $800,000 US ($1,137,868 CAD) in new funding to advance a promising therapy for multiple sclerosis (MS).

15 Sep 2025

Texas Tech research team earns $3 million renewal to advance stroke therapy

Stroke research aims to understand the brain's self-protective and repair mechanisms. Gaining detailed insight into these mechanisms is crucial as such knowledge could lead to newly developed medications and interventions which mimic or engage the brain's self-protective/repair mechanisms, leading to innovative stroke therapies.

13 Sep 2025

Novel vitamin K analogs show promise for reversing neurodegenerative diseases

Neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's disease are characterized by the progressive loss of neurons.

13 Sep 2025

TRIMTECH Therapeutics establishes Scientific Advisory Board

TRIMTECH Therapeutics, a biotech company creating novel, small molecule therapeutics that selectively degrade protein aggregates, to combat neurodegenerative diseases, today announced the formation of its Scientific Advisory Board (SAB).

From TRIMTECH Therapeutics 3 Sep 2025

How plant compounds could target Alzheimer’s disease from multiple angles

This review highlights how dietary polyphenols modulate Alzheimer’s disease biology through antioxidant, anti-inflammatory, and multi-target mechanisms, supported by in-silico docking analyses. Despite promise, challenges in bioavailability and brain delivery remain key hurdles to clinical translation.

31 Aug 2025

New oral antiretroviral shows potential as long-acting HIV pre-exposure prophylaxis

A new HIV antiretroviral shows promise as a long-acting, oral prophylactic agent, according to a new study by Izzat Raheem, Tracy Diamond and colleagues from Merck & Co., Inc., Rahway, NJ, USA, published August 26th in the open-access journal PLOS Biology.

26 Aug 2025

Balancing speed and selectivity is key for designing effective targeted covalent inhibitors

One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs).

22 Aug 2025

New 'dual-mode' tracer agent enhances precision in prostate cancer procedures

A preclinical evaluation of a new 'dual-mode' tracer agent shows promise in not only helping surgeons image and plan prostate cancer procedures, but also provide them with much more consistent and targeted guidance during surgery.

21 Aug 2025

Artificial intelligence enables discovery of novel compounds to fight drug-resistant bacteria

With help from artificial intelligence, MIT researchers have designed novel antibiotics that can combat two hard-to-treat infections: drug-resistant Neisseria gonorrhoeae and multi-drug-resistant Staphylococcus aureus (MRSA).

14 Aug 2025

Researchers unveil drug complex that makes cancer cells self-report to immune system

Two junior research groups at Ruhr University Bochum, Germany, have developed a drug complex that kills cancer cells in such a clever manner that they raise a red flag as they die. They signal to the immune system that something is seriously wrong with this type of cell.

18 Jul 2025

Flawed coronavirus model prompts urgent reassessment for drug developers

The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections.

4 Jul 2025

Innovative approach for the development of next-generation cancer therapies targeting FGFR2/3

Aberrations in fibroblast growth factor receptors FGFR2/3 are major drivers of many cancers-including intrahepatic cholangiocarcinoma, endometrial, breast, gastric, and bladder cancers.

4 Jul 2025

Traditional South Asian medicinal plants show promise in addressing memory disorders

The growing global population of elderly individuals has led to a dramatic rise in chronic diseases, including neurocognitive disorders such as Alzheimer's disease.

27 May 2025

New candidate compounds show promise for Alzheimer's and pain treatment

A study published in the Journal of Medicinal Chemistry presents a new family of candidate compounds for the treatment of Alzheimer's disease and pain, which have shown promising effects in animal models.

14 May 2025

New glycopeptide antibiotic discovered to combat resistant bacteria

An international team of researchers, led by the University of Vienna and the Helmholtz Institute for Pharmaceutical Research Saarland, has discovered saarvienin A, a new type of glycopeptide antibiotic.

14 May 2025

Long-acting HIV drug emerges from decades of research and advocacy

In the hunt for a remedy, when the baton is passed from dedicated academic scientists to an innovative company to trusted community advocates, outcomes for society can be especially powerful.

8 May 2025

Scientists engineer new drug candidate to fight deadly mycobacterial infection

In a classic example of scientific problem solving, scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) and colleagues have published a paper introducing a promising new drug candidate they engineered to target a deadly and emerging infection.

6 May 2025