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Study advances understanding of mixed protein pathologies in dementia

The aging brain frequently harbors multiple protein pathologies that contribute to Alzheimer's, Parkinson's and other neurodegenerative diseases.

8 Jul 2026

Study identifies new target for Parkinson's disease neuroprotection

Parkinson's disease (PD) is the second most common form of neurodegenerative disease and afflicts more than ten million people worldwide. While current therapies address disease symptoms, they do not prevent the underlying neurodegeneration that drives the disease.

8 Jul 2026

Biohub researchers use artificial intelligence to uncover new psoriasis targets

Biohub researchers performed what they believe is the first genome-wide CRISPR study of primary human adult skin cells, then used an AI model to mine the results for overlooked drug targets for psoriasis.

8 Jul 2026

Investigational drug ameliorates neuronal DNA damage and inflammation in Alzheimer's model

Accumulation of DNA damage in the brain's neurons may contribute to the development of Alzheimer's disease.

8 Jul 2026

New molecular mechanism identified in common inherited heart disease

A study led by the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), working in collaboration with an international research team, has identified a new molecular mechanism involved in hypertrophic cardiomyopathy, the most common inherited cardiovascular disease.

7 Jul 2026

Study identifies promising drug target to prevent neurodegenerative conditions

6 Jul 2026

Study compares different light therapies for treating Alzheimer's disease

The researchers treated 5‑month‑old 5xFAD mice – a model with aggressive amyloid deposition – with 810‑nm light (25 mW/cm² at the scalp, ~6.25 mW/cm² brain dose for CW, and half that for 40‑Hz due to 50% duty cycle) for 10 minutes daily over 37 days.

6 Jul 2026

Engineered scaffold restores skull growth in craniosynostosis mouse models

An engineered triphasic biomaterial scaffold successfully recreated the cranial suture stem cell niche lost in craniosynostosis, a condition that causes premature fusion of skull bones.

5 Jul 2026

Engineered CAR T cells show promise against myeloproliferative neoplasms

A new form of CAR T cell therapy has been designed to find and destroy the cancer-driving stem cells responsible for a group of blood cancers known as myeloproliferative neoplasms (MPNs), while leaving healthy blood cells unharmed, in new research led by UCL and University of Oxford researchers.

1 Jul 2026

Rare genetic condition offers new insights into human aging process

Scientists have discovered a rare genetic condition which causes people to age at a much faster rate, offering fresh insights into the aging process.

30 Jun 2026

New strategy restores vancomycin effectiveness against resistant bacteria

Antibiotic resistance is one of the most urgent threats to global health, linked to an estimated 4.7 million deaths worldwide in 2019 alone.

29 Jun 2026

Smoking reprograms immune cells to accelerate cardiovascular disease

Scientists at the University of Oklahoma have identified a previously unrecognized immune system pathway that helps explain how cigarette smoking increases the risk of cardiovascular disease.

29 Jun 2026

Anti-inflammatory molecule reduces excessive alcohol consumption in female mice

The drugs that keep rheumatoid arthritis in check may one day help people stop drinking. A new Scripps Research study shows that an anti-inflammatory molecule, already approved by the U.S. Food and Drug Administration to treat autoimmune diseases, reduces excessive alcohol consumption in alcohol-dependent female mice.

29 Jun 2026

New viral model triggers Parkinson's symptoms without using toxins

Scientists usually use animal models when studying Parkinson's disease because these models mimic the disease well.

29 Jun 2026

Scientists discover how Arc protein spreads Alzheimer's brain pathology

Alzheimer's disease is driven by a buildup of a toxic protein called Tau that kills neurons. As toxic Tau spreads to new regions of the brain, symptoms become worse and ultimately fatal.

29 Jun 2026

Smart nanoplatform uses wound acidity to trigger accelerated healing

Infected wounds pose a significant medical challenge, often leading to delayed healing and complications due to bacterial biofilms and excessive inflammation.

26 Jun 2026

Gene linked to lower BMI points researchers toward a new obesity target

A review in Cardiology in Review highlights GPR75, a receptor for 20-HETE, as a promising therapeutic target for obesity and metabolic syndrome. Evidence from genetic studies, cell experiments, and mouse models suggests that blocking this pathway could influence weight gain, insulin resistance, hypertension, inflammation, and vascular dysfunction.

25 Jun 2026