Restless Legs Syndrome News and Research

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Restless legs syndrome (RLS) is a neurological disorder characterized by unpleasant sensations in the legs and an uncontrollable urge to move when at rest in an effort to relieve these feelings. RLS sensations are often described by people as burning, creeping, tugging, or like insects crawling inside the legs. Often called paresthesias (abnormal sensations) or dysesthesias (unpleasant abnormal sensations), the sensations range in severity from uncomfortable to irritating to painful.

The most distinctive or unusual aspect of the condition is that lying down and trying to relax activates the symptoms. As a result, most people with RLS have difficulty falling asleep and staying asleep. Left untreated, the condition causes exhaustion and daytime fatigue. Many people with RLS report that their job, personal relations, and activities of daily living are strongly affected as a result of their exhaustion. They are often unable to concentrate, have impaired memory, or fail to accomplish daily tasks.
FDA approves Horizant Extended-Release Tablets for Restless Legs Syndrome

FDA approves Horizant Extended-Release Tablets for Restless Legs Syndrome

XenoPort reports preliminary top-line results from arbaclofen placarbil Phase 2b clinical trial in GERD

XenoPort reports preliminary top-line results from arbaclofen placarbil Phase 2b clinical trial in GERD

Study: Daily hemodialysis can help alleviate sleep problems related to RLS

Study: Daily hemodialysis can help alleviate sleep problems related to RLS

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

XenoPort prices underwritten offering of common stock

XenoPort prices underwritten offering of common stock

Restless legs syndrome during pregnancy may reappear later on

Restless legs syndrome during pregnancy may reappear later on

XenoPort receives grant from Michael J. Fox Foundation to support Parkinson's disease therapies

XenoPort receives grant from Michael J. Fox Foundation to support Parkinson's disease therapies

XenoPort third quarter net loss decreases to $19.9 million

XenoPort third quarter net loss decreases to $19.9 million

FDA reviews GSK's response to Complete Response letter for Horizant

FDA reviews GSK's response to Complete Response letter for Horizant

People hospitalized after stroke on a weekend more likely to die: Study

People hospitalized after stroke on a weekend more likely to die: Study

Study suggests treating RLS may improve sleep and quality of life in people with fibromyalgia

Study suggests treating RLS may improve sleep and quality of life in people with fibromyalgia

XenoPort to present XP23829 preclinical data at ECTRIMS meeting

XenoPort to present XP23829 preclinical data at ECTRIMS meeting

New video PSA may help raise donation for brain research

New video PSA may help raise donation for brain research

Neupro improves quality of life in Parkinson's disease patients

Neupro improves quality of life in Parkinson's disease patients

Research shows dexamethasone treatment effective for bacterial meningitis

Research shows dexamethasone treatment effective for bacterial meningitis

XenoPort to present XP21279 clinical trial data at World Parkinson Congress meeting

XenoPort to present XP21279 clinical trial data at World Parkinson Congress meeting

XenoPort intends to initiate Phase 3 XP19986 trial for multiple sclerosis

XenoPort intends to initiate Phase 3 XP19986 trial for multiple sclerosis

XenoPort announces equity award to new employee under 2010 Inducement Plan

XenoPort announces equity award to new employee under 2010 Inducement Plan

Overweight, smoking and lack of exercise linked to frequent headaches in teens

Overweight, smoking and lack of exercise linked to frequent headaches in teens

Study finds lithium drugs not effective for amyotrophic lateral sclerosis treatment

Study finds lithium drugs not effective for amyotrophic lateral sclerosis treatment

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