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Investigational oral form of treatment offers hope for adults with acromegaly

Adults who need medical maintenance treatment of the growth hormone disorder acromegaly respond well to an investigational oral form of the drug octreotide, investigators of the Chiasma OPTIMAL study reported.

31 Mar 2020

Discovery Of Gabaergic Synaptic Regulations Inside The Brain For A New Epilepsy Treatment

DGIST announced on February 12 that the joint research team of Professor Jaewon Ko and Professor Ji Won Um in the Department of Brain and Cognitive Sciences found a new candidate target to treat epilepsy by regulating GABAergic synaptic functions

3 Mar 2020

Targeted combinatorial drug treatment restores beta cell function in mice

The loss of the identity of insulin-secreting beta cells in the islet of Langerhans, a process also called beta cell dedifferentiation, has been proposed to be a main reason for the development of diabetes.

20 Feb 2020

Scientists discover specific neurons that promote reward-like behaviors, alcohol consumption

Scientists have known that a region of the brain called the central nucleus of the amygdala (CeA) plays a role in behaviors related to alcohol use and consumption in general. It's been less known which precise populations of brain cells and their projections to other brain regions mediate these behaviors.

12 Dec 2019

Study evaluates role of PET/CT in selecting candidates for peptide receptor radionuclide therapy

A new study published in The Journal of Nuclear Medicine evaluated the role of 68Ga-DOTATATE positron emission tomography/computed tomography in selecting neuroendocrine tumor patients who may benefit from peptide receptor radionuclide therapy.

9 Oct 2019

New class of radiopharmaceuticals offer fresh perspective on cancer imaging, theranostics

Research presented at the 2019 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging describes a new class of radiopharmaceuticals, named radiohybrids, that offer a fresh perspective on cancer imaging and radioligand therapy.

26 Jun 2019

Insulin-producing beta cells can change their function in diabetes, reveals study

A revolutionary new study using only materials derived from humans has revealed that insulin-producing beta cells can change their function in diabetes - and that this change may be reversible.

17 May 2019

Novel preclinical model mimics persistent interneuron loss seen in preterm infants

Research-clinicians at Children's National Health System have created a novel preclinical model that mimics the persistent interneuron loss seen in preterm human infants, identifying interneuron subtypes that could become future therapeutic targets to prevent or lessen neurodevelopmental risks, the team reports Jan. 31, 2019, in eNeuro.

20 Feb 2019

Human cells can change their original function to battle against diabetes

For the first time, researchers have shown that ordinary human cells can change their original function. This may give new hope for diabetes patients.

14 Feb 2019

MGH researchers identify brain cells that modulate behavioral response to threats

A team of investigators from the Massachusetts General Hospital (MGH) Center for Regenerative Medicine has identified a population of brain cells that appears to play a role in calibrating behavioral responses to potentially threatening situations.

12 Feb 2019

Discovery may lead to new form of treatment for diabetes

Diabetes is caused by damaged or non-existing insulin cells inability to produce insulin, a hormone that is necessary in regulating blood sugar levels. Many diabetes patients take insulin supplements to regulate these levels.

7 Jan 2019

Researchers identify new region in mouse brain that affects appetite and body weight

Researchers at A*STAR's Singapore Bioimaging Consortium have identified a new region of the mouse brain called the Tuberal Nucleus, which affects appetite and body weight

13 Jul 2018

Study shows benefits, safety of long-lasting radionuclide therapy for patients with advanced NETs

A first-in-human study presented at the 2018 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging demonstrates the benefits and safety of a new, long-lasting type of radionuclide therapy for patients with advanced, metastatic neuroendocrine tumors.

26 Jun 2018

New FDA-approved therapy provides better quality of life for patients with midgut neuroendocrine tumors

Midgut neuroendocrine tumors are a rare type of cancer that develops in the small intestine and colon. Roughly 12,000 people are diagnosed with this disease each year. In January, the United Stated Food and Drug Administration approved Lutathera, a first-of-its-kind peptide receptor radionuclide therapy.

12 Jun 2018

New nuclear medicine method appears to effectively detect neuroendocrine tumors

Researchers have shown that a new nuclear medicine procedure could safely and more effectively detect cancerous gastrointestinal and pancreatic neuroendocrine tumors than current methods.

7 Jun 2018

Scientists identify neural circuit that gives rise to anxiety

Neuroscientists at Cold Spring Harbor Laboratory have identified a neural circuit in the amygdala, the brain's seat of emotion processing, that gives rise to anxiety.

29 May 2018

FDA approves new radioactive drug for treatment of rare digestive tract cancers

The U.S. Food and Drug Administration today approved Lutathera (lutetium Lu 177 dotatate) for the treatment of a type of cancer that affects the pancreas or gastrointestinal tract called gastroenteropancreatic neuroendocrine tumors (GEP-NETs).

29 Jan 2018

Researchers find surprising differences in first-ever whole-brain map of inhibitory neurons

Researchers at Penn State College of Medicine have collaborated on the first-ever quantitative whole-brain map of inhibitory neurons in the mouse brain. These brain cells play a crucial role in regulating response to stimuli and have been widely implicated in many psychiatric conditions.

6 Oct 2017

Novel peptide receptor radionuclide therapy improves wellbeing of neuroendocrine cancer patients

Malignant neuroendocrine tumors, commonly called NETs, are easy to miss and associated with discouraging survival rates and poor quality of life.

13 Jun 2017

Specialized nerve cells play key role in controlling information flow in the brain, study finds

Specialized nerve cells, known as somatostatin-expressing (Sst) interneurons, in the outer part of the mammalian brain (or cerebral cortex) — play a key role in controlling how information flows in the brain when it is awake and alert.

3 Mar 2017