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Oral targeted therapy shrinks tumors in over 70% of patients with HER2-mutant NSCLC

The oral targeted therapy sevabertinib led to tumor reduction and manageable side effects in patients with HER2-mutant non-small cell lung cancer (NSCLC), according to data from a trial led by researchers at The University of Texas MD Anderson Cancer Center.

22 Oct 2025

Tracking daily blood pressure in pregnancy could predict low birth weight sooner

Early-pregnancy home blood pressure patterns reveal that even small cumulative elevations, not just high averages, raise the risk of low birth weight. Tracking daily readings above thresholds may improve early warning and maternal–fetal outcomes.

21 Oct 2025

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

A multicenter Phase II clinical trial led by researchers at The University of Texas MD Anderson Cancer Center demonstrated significant tumor shrinkage and disease control in patients with advanced pheochromocytoma and paraganglioma (PPGL), two rare and potentially life-threatening neuroendocrine tumors.

18 Oct 2025

Osimertinib plus chemotherapy improves survival in EGFR-mutated lung cancer

Treatment with osimertinib plus a platinum–pemetrexed chemotherapy combination resulted in statistically significant and clinically meaningful improvement in overall survival in patients with newly diagnosed EGFR-mutated advanced non-small cell lung cancer (NSCLC) compared to osimertinib alone.

17 Oct 2025

Common food additives may trigger childhood asthma

Researchers utilize metabolomics to investigate the mechanisms underlying the association between food additives and childhood asthma.

6 Oct 2025

Dipeptides reveal clues to the origin of life’s instructions

Genes are the building blocks of life, and the genetic code provides the instructions for the complex processes that make organisms function.

17 Sep 2025

HIIT boosts anti-cancer proteins and slows breast cancer growth

Both resistance training and HIIT enhance myokine levels and suppress breast cancer cell growth, supporting exercise as a therapeutic strategy for survivors.

15 Sep 2025

Osimertinib plus chemotherapy offers overall survival advantage for patients with EGFR-mutated advanced NSCLC

Final overall survival (OS) results from the Phase III FLAURA2 trial demonstrate that first-line osimertinib plus chemotherapy significantly improves OS compared to osimertinib monotherapy in patients with EGFR-mutated (EGFRm) advanced non-small cell lung cancer (NSCLC).

8 Sep 2025

Ivonescimab plus chemotherapy provides survival benefit for difficult-to-treat NSCLC patients

Adding ivonescimab, a first-in-class bispecific antibody targeting both PD-1 and VEGF, to chemotherapy significantly prolonged progression-free survival (PFS) compared to chemotherapy alone in patients with advanced non-small cell lung cancer (NSCLC) harboring EGFR mutations whose disease progressed on third-generation EGFR tyrosine kinase inhibitors (TKIs).

8 Sep 2025

Glutamate receptors found to drive pediatric brain tumor development

The most common type of brain tumor in children, pilocytic astrocytoma (PA), accounts for about 15% of all pediatric brain tumors.

1 Sep 2025

University of Vienna team develops method to measure molecular charges

An international research team led by the University of Vienna has succeeded in developing a new method to directly measure partial charges in molecules. The results, now published in Nature, provide new insights into molecular interactions and offer potential applications in drug development and materials science.

22 Aug 2025

How dietary formaldehyde links to worsening diabetes and memory loss

A new review reveals how everyday foods and hidden exposures to formaldehyde may fuel insulin resistance and chip away at memory, but also points to dietary patterns and emerging therapies that could help reduce the risk.

20 Aug 2025

Targeting the adrenomedullin pathway may be a potential therapy for liver failure

Liver failure syndromes are characterized by a dysregulated immune response leading to immune paralysis. Adrenomedullin (ADM) is a potent vasodilator and immunoregulator.

18 Aug 2025

Drug turns human blood into a mosquito killer

A drug that makes human blood lethal to mosquitoes also acts as a potent contact insecticide absorbed through the feet, providing a promising new approach to combating insecticide resistance.

7 Aug 2025

New blood test detects early-stage solid tumors with high accuracy

Current methods for cancer diagnosis are based on identifying biomarkers - molecules that reveal a particular state or process in the body – produced by the tumor or associated proteins.

31 Jul 2025

Blocking PTP1B protects the heart from obesity-induced damage

A groundbreaking new study led by researchers at the Masonic Medical Research Institute (MMRI) has identified a promising molecular target to protect the heart against damage caused by high-fat diet and obesity.

22 Jul 2025

FAU neuroscientist receives NIH grant to study amphetamine effects on the brain

Lucia Carvelli, Ph.D., associate professor of neuroscience at Florida Atlantic University's Harriet L. Wilkes Honors College and a member of the FAU Stiles-Nicholson Brain Institute, has received a $571,675 grant from the National Institutes of Health to advance critical research into how amphetamines affect brain function.

15 Jul 2025

Tyrosine News and Research

Oral targeted therapy shrinks tumors in over 70% of patients with HER2-mutant NSCLC

Tracking daily blood pressure in pregnancy could predict low birth weight sooner

Belzutifan demonstrates strong clinical activity in two rare neuroendocrine tumors

Osimertinib plus chemotherapy improves survival in EGFR-mutated lung cancer

Common food additives may trigger childhood asthma

Dipeptides reveal clues to the origin of life’s instructions

HIIT boosts anti-cancer proteins and slows breast cancer growth

Osimertinib plus chemotherapy offers overall survival advantage for patients with EGFR-mutated advanced NSCLC

Ivonescimab plus chemotherapy provides survival benefit for difficult-to-treat NSCLC patients

Glutamate receptors found to drive pediatric brain tumor development

University of Vienna team develops method to measure molecular charges

How dietary formaldehyde links to worsening diabetes and memory loss

Targeting the adrenomedullin pathway may be a potential therapy for liver failure

Drug turns human blood into a mosquito killer

New blood test detects early-stage solid tumors with high accuracy

Blocking PTP1B protects the heart from obesity-induced damage

FAU neuroscientist receives NIH grant to study amphetamine effects on the brain

Dual targeting of lipid kinases offers hope against emerging viruses

Understanding resistance to EGFR targeted therapies in head and neck cancers and breast cancer

Aromatic benzaldehyde inhibits growth of therapy-resistant pancreatic cancer

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