Central Nervous System News and Research

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New study reveals alarming cognitive impairments in long COVID patients

Persistent COVID-19 symptoms can lead to cognitive deficits in recovered patients. This systematic review highlights the need for further research and interventions to address long-term cognitive impairments.

28 Jun 2023

Looking into the future: infant visual preference for mother's face predicts emotional resilience

Investigated the trajectories of infant visual preference for the mother's face and how these are related to the development.

26 Jun 2023

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA, plays an important role in molecular biology.

21 Jun 2023

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

A new study in rats suggests that xylazine, the active ingredient in a non-opioid veterinary tranquilizer not approved for human use, can worsen the life-threatening effects of opioids.

21 Jun 2023

Rare sugars in a diabetic diet: the efficacy of a D-allulose-containing diet in patients with type two diabetes

Researchers evaluated the effectiveness of diabetic diets containing D-allulose among type 2 diabetes patients.

21 Jun 2023

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

Researchers evaluated the function of the zinc finger transcription factor ROB1 and its two phenotypically distinct alleles in the pathogenesis of Candida albicans infections.

20 Jun 2023

CBD and THC: promising remedies for aluminum-related neurological damage

Researchers assessed the protective effect of CBD and THC oils against aluminum toxicity.

20 Jun 2023

Cortical thinning in young adults with history of heavy drinking since adolescence is linked to altered neurotransmission

During adolescence, the brain undergoes intense development and is particularly susceptible to the deleterious effects of alcohol use. According to findings from a recent follow-up study in Finland, young adults whose heavy drinking began in adolescence have lower cortical gray matter thickness and altered neurotransmission.

19 Jun 2023

Adagrasib shows promise for the treatment of patients with KRAS G12C-mutated non-small cell lung cancer

Researchers from The University of Texas MD Anderson Cancer Center found the KRAS G12C inhibitor adagrasib showed promising activity suppressing cancer growth not only within the lungs but also in brain metastases for patients with KRAS G12C-mutated non-small cell lung cancer.

16 Jun 2023

Brain microglia serve as a stable viral reservoir for latent HIV

As a part of its life cycle, the human immunodeficiency virus-1 (HIV) inserts a copy of its DNA into human immune cells. Some of these newly infected immune cells can then transition into a dormant, latent state for a long period of time, which is referred to as HIV latency.

16 Jun 2023

Does taurine deficiency speed up aging?

The association of the amino acid taurine with aging.

16 Jun 2023

Light to moderate alcohol consumption lowers cardiovascular risk through stress reduction

The beneficial effects of light/moderate alcohol consumption on cardiovascular disease risk may be due to its ability to attenuate stress.

15 Jun 2023

Insilico announces new multimodal transformer-based aging clock for processing diverse data sets

Clinical stage generative artificial intelligence (AI)-driven drug discovery company Insilico Medicine ("Insilico") has announced a new multimodal transformer-based aging clock that is capable of processing diverse data sets and providing insights into biomarkers for aging, mapping them to genes relevant to both aging and disease, and discovering new therapeutic targets designed to slow or reverse both aging and aging-related diseases.

15 Jun 2023

Vaginal seeding engrafts maternal bacteria in the bodies of cesarean section born neonates

Newborns delivered by cesarean section who are swabbed with the vaginal fluid of their mothers after birth have beneficial bacteria restored to their skin surface and stools, according to a new study.

14 Jun 2023

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Obesity-induced neuroinflammation significantly contributes to the pathophysiology of depression and Alzheimer's disease. Targeting midlife stage for intervention is crucial to potentially prevent Alzheimer's pathology.

13 Jun 2023

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Review discusses the increasing importance of two-dimensional nanomaterials like graphene in neuroscience, highlighting their potential in nerve repair, creating brain-mimicking synaptic devices, and treating neurological disorders. It also considers the challenges and future prospects of these materials in this complex field.

11 Jun 2023

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM6331, a potential best-in-class pan-TEAD inhibitor, as a preclinical candidate compound (PCC) generated by Chemistry42, its proprietary generative chemistry-driven molecule design engine, targeting the Hippo pathway for the treatment of advanced solid tumors.

8 Jun 2023

Targeted therapy for non-small cell lung cancer provides benefit to patients after surgery

A clinical trial led by Yale Cancer Center shows that the drug osimertinib, a targeted therapy for non-small cell lung cancer, improved rates of survival and reduced risk of recurrence in patients after surgery.

7 Jun 2023

Progesterone could be used in the fight against Parkinson’s disease

Progesterone was shown in a study to have a protective effect on intestine nerve cells. These findings raise hopes that the hormone could be used in the fight against Parkinson’s disease.

6 Jun 2023

Microparticle-delivered therapy likely to be the first step toward stopping autoimmune diseases

According to the federal government's National Institute of Neurological Disorders and Stroke, nearly 3 million people worldwide - with almost a third in the United States - are living with multiple sclerosis (MS), a disabling neurological disease in which the body's immune system mistakenly attacks nerves feeding information to the central nervous system (the brain and spinal cord). Although rarely fatal, MS can lead to long-term disabilities, and impair movement, muscle control, vision and cognition.

6 Jun 2023

Central Nervous System News and Research

New study reveals alarming cognitive impairments in long COVID patients

Looking into the future: infant visual preference for mother's face predicts emotional resilience

Alternative splicing in neurodegenerative disease and the promise of RNA-based therapeutic strategies

Xylazine can exacerbate the life-threatening effects of opioids, rat study shows

Rare sugars in a diabetic diet: the efficacy of a D-allulose-containing diet in patients with type two diabetes

The contribution of transcription factor ROB1 to the pathophysiology of C. albicans-induced candidal infections

CBD and THC: promising remedies for aluminum-related neurological damage

Cortical thinning in young adults with history of heavy drinking since adolescence is linked to altered neurotransmission

Adagrasib shows promise for the treatment of patients with KRAS G12C-mutated non-small cell lung cancer

Brain microglia serve as a stable viral reservoir for latent HIV

Does taurine deficiency speed up aging?

Light to moderate alcohol consumption lowers cardiovascular risk through stress reduction

Insilico announces new multimodal transformer-based aging clock for processing diverse data sets

Vaginal seeding engrafts maternal bacteria in the bodies of cesarean section born neonates

Connecting the inflammatory dots: Obesity, depression, and Alzheimer's linked by neuroinflammation

Revolution in neuroscience: 2D nanomaterials propel advances in brain repair, treatment, and diagnosis

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Targeted therapy for non-small cell lung cancer provides benefit to patients after surgery

Progesterone could be used in the fight against Parkinson’s disease

Microparticle-delivered therapy likely to be the first step toward stopping autoimmune diseases

Event guide: The 7th CNS Drug Delivery Summit eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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