GlaxoSmithKline News and Research

RSS

Alzheimer's vaccine - First evidence for efficacy

AFFiRiS' Alzheimer's vaccine candidate AD02 showed indicative evidence for potential efficacy in a phase I clinical trial. This was demonstrated by the analysis of the data from secondary clinical study endpoints.

12 Mar 2011

Otelixizumab Phase 3 DEFEND-1 study in new-onset autoimmune type 1 diabetes does not meet primary endpoint

Tolerx, Inc. and GlaxoSmithKline (GSK) today announced that the Phase 3 DEFEND-1 study of otelixizumab, an investigational humanized anti-CD3 monoclonal antibody, did not meet the primary efficacy endpoint of change in C-peptide at month 12 in patients with new-onset autoimmune type 1 diabetes.

11 Mar 2011

Scientific advances at Scripps Research lay foundation for new lupus drug Benlysta

Scientific advances at The Scripps Research Institute were key to laying the foundation for the new drug Benlysta® (belimumab), approved today by the U.S. Food and Drug Administration. Benlysta®, which treats the most common type of lupus, is the first in a new class of pharmaceuticals that prevents the body from attacking its own critical tissues.

11 Mar 2011

GSK announces new NovaMin-containing dental formulation for sensitive teeth

This year, for the first time, millions of Americans will be protecting their sensitive teeth with NovaMin in everyday dental products. Co-inventor Gary Hack, DDS, couldn't be happier.

11 Mar 2011

FDA approves BENLYSTA for active, autoantibody-positive systemic lupus erythematosus

Human Genome Sciences, Inc. and GlaxoSmithKline PLC today announced that the U.S. Food and Drug Administration has approved BENLYSTA® (belimumab) for the treatment of adult patients with active, autoantibody-positive systemic lupus erythematosus (SLE) who are receiving standard therapy.

10 Mar 2011

Human Genome Sciences receives FDA approval for Benlysta to treat lupus

The U.S. Food and Drug Administration today approved Benlysta to treat patients with active, autoantibody-positive lupus who are receiving standard therapy, including corticosteroids, antimalarials, immunosuppressives, and nonsteroidal anti-inflammatory drugs.

9 Mar 2011

New clinical trial to assess antiretroviral treatment in HIV-infected individuals based on CD4 counts

A major new clinical trial seeks to determine whether HIV-infected asymptomatic individuals have less risk of developing AIDS or other serious illness if they begin taking antiretrovirals sooner rather than later, based on their level of CD4+ T-cells.

8 Mar 2011

New Lupus drug marching towards approval

A new drug for lupus from the Human Genome Sciences Inc is all set to get clearance in the US this week. If all goes through, this drug will offer patients the first approved treatment option in a half-century, setting the manufacturer up for huge sales.

7 Mar 2011

Joslin launches initiative for primary care physicians to improve diabetes care

Joslin Diabetes Center has launched a groundbreaking initiative for primary care physicians to improve diabetes care.

3 Mar 2011

Meda launches Medivir's cold sore treatment Xerese in the U.S.

Medivir AB, the emerging research-based specialty pharmaceutical company focused on infectious diseases, today announces that the Company's commercialization partner, Meda AB, has launched Medivir's unique cold sore treatment Xerese in the United States.

1 Mar 2011

AFFiRiS announces significant progress in collaboration with GSK for Alzheimer's vaccine development

AFFiRiS AG announced today significant progress in their collaboration with GlaxoSmithKline Biologicals for the development of an active vaccination programme against Alzheimer's disease.

1 Mar 2011

AFFiRiS AG - Alzheimer's vaccines generate further cash flow

AFFiRiS AG announced today significant progress in their collaboration with GlaxoSmithKline Biologicals (GSK) for the development of an active vaccination programme against Alzheimer´s disease. While the lead vaccine candidate AD02 is currently in phase II clinical testing, two additional preclinical programmes have been completed successfully. The second programme was related to alternative vaccine candidates generated by AFFiRiS´ AFFITOME® technology, including candidate AD03. Based on the promising preliminary results of this programme, GSK exercised its option for the alternative vaccine candidates which triggered a EUR 2.5 million payment to AFFiRiS. An additional EUR 1 million payment became due simultaneously for the successful completion of tests of alternative vaccine formulations.

28 Feb 2011

FDA approves GSK's PROMACTA to treat rare blood disorder

GlaxoSmithKline today announced that the United States Food and Drug Administration granted full approval for PROMACTA, an oral tablet that can raise platelet counts in patients with the rare blood disorder chronic immune thrombocytopenic purpura who have had an insufficient response to corticosteroids, immunoglobulins or splenectomy.

27 Feb 2011

Experts at ICAO warn about risk of cardiometabolic consequences in overweight individuals

Experts meeting at the 2nd International Congress on Abdominal Obesity today issued a warning that millions of individuals around the globe are at risk from the cardiometabolic consequences of being overweight. Worryingly, the experts suggest that these people are not being identified by their doctors.

25 Feb 2011

Report finds neglected diseases research funding up in 2009, funding for related non-profits down

"A rise in global funding for research into neglected diseases needs to be matched by a continued focus on delivering practical new ways to curb sickness in the developing world," according to the third annual report by the Global Funding of Innovation for Neglected Diseases released on Wednesday, Reuters reports.

18 Feb 2011

Amicus to present additional positive data from Amigal Phase 2 extension study for Fabry disease

Amicus Therapeutics today announced that additional positive data from the ongoing Phase 2 extension study of its investigational drug Amigal™ (migalastat HCl) for Fabry disease will be presented at the Lysosomal Disease Network WORLD Symposium in Las Vegas, Nevada, February 16-18th, 2011.

17 Feb 2011

Flu vaccine update

This new vaccine which could become available in the United States in the next few years, is made by growing the influenza virus in cultures of animal cells rather than in the chicken eggs that have been used for more than five decades. This shortens the process by six months. Using animal cells, which are grown in enclosed steel tanks, also reduces the risk of bacterial contamination, which has led to shortages of seasonal vaccines in some years. The study was reported in The Lancet this Tuesday.

16 Feb 2011

Also in global health news: Gates Foundation global health head to step down; drug, medical supply shortages in Gaza; food security in N. Korea

Tachi Yamada, president of the global health program at the Bill & Melinda Gates Foundation, on Monday announced he would step down in June after five years serving in the position, the Associated Press/Seattle Post-Intelligencer reports.

16 Feb 2011

GAVI chair calls for greater reductions in vaccine prices for developing countries

On Monday, the same day the GAVI Alliance helped oversee the roll out of a routine pneumococcal vaccine in Kenya, GAVI chairman Dagfinn Hoybraten highlighted the need for greater reductions in vaccine prices in developing countries during an interview with Reuters, the news service reports. The piece examines the funding mechanism in place to finance the pneumococcal vaccines, known as Advance Market Commitment (AMC), as well as the budget shortfall facing the group (Kelland, 2/14).

16 Feb 2011

Pneumococcal vaccine officially rolled out in Kenya

"Kenya on Monday became the first African country to introduce a routine vaccine against pneumococcal disease, which claims the lives of more than half a million children under five each year," Deutsche Presse Agentur/The Hindu reports. The GAVI Alliance, which is supporting the vaccine's roll out, "is aiming to introduce the vaccine to 19 developing countries - including Nicaragua, Guyana, Yemen and Sierra Leone - within a year and hopes to reach more than 40 nations by 2015, depending on funding."

15 Feb 2011

GlaxoSmithKline News and Research

Alzheimer's vaccine - First evidence for efficacy

Otelixizumab Phase 3 DEFEND-1 study in new-onset autoimmune type 1 diabetes does not meet primary endpoint

Scientific advances at Scripps Research lay foundation for new lupus drug Benlysta

GSK announces new NovaMin-containing dental formulation for sensitive teeth

FDA approves BENLYSTA for active, autoantibody-positive systemic lupus erythematosus

Human Genome Sciences receives FDA approval for Benlysta to treat lupus

New clinical trial to assess antiretroviral treatment in HIV-infected individuals based on CD4 counts

New Lupus drug marching towards approval

Joslin launches initiative for primary care physicians to improve diabetes care

Meda launches Medivir's cold sore treatment Xerese in the U.S.

AFFiRiS announces significant progress in collaboration with GSK for Alzheimer's vaccine development

AFFiRiS AG - Alzheimer's vaccines generate further cash flow

FDA approves GSK's PROMACTA to treat rare blood disorder

Experts at ICAO warn about risk of cardiometabolic consequences in overweight individuals

Report finds neglected diseases research funding up in 2009, funding for related non-profits down

Amicus to present additional positive data from Amigal Phase 2 extension study for Fabry disease

Flu vaccine update

Also in global health news: Gates Foundation global health head to step down; drug, medical supply shortages in Gaza; food security in N. Korea

GAVI chair calls for greater reductions in vaccine prices for developing countries

Pneumococcal vaccine officially rolled out in Kenya

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News