High Throughput News and Research

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Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Researchers developed a novel high-throughput method to obtain monoclonal antibodies from COVID-19 individuals infected with SARS-CoV-2 ancestral strain Wuhan-Hu-1 and the Beta or Gamma variants.

1 Apr 2022

Study identifies a new class of monoclonal antibodies that neutralize both alpha and beta coronaviruses

A team of international scientists has recently isolated and characterized pan-coronavirus neutralizing antibodies from individuals with pre-existing immunity against SARS-CoV-2.

1 Apr 2022

A summary of SARS-CoV-2 RNA-protein interactome studies

A new study summarized the importance of SARS-CoV-2 ribonucleic acid protein interactomes in the study of RNA viruses.

30 Mar 2022

Immunity against SARS-CoV-2 BA.1, BA.2, and BA.3 after three doses of BNT162b2 vaccine

A new study assesses the neutralization of three Omicron sublineages by BNT162b2-vaccinated sera collected one month after the third vaccine dose. A preprint version of the study is available on the bioRxiv* server while the article undergoes peer review.

29 Mar 2022

Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

A new study assessed the molecular dynamics of potentially active natural phytochemicals to target the SARS-CoV-2 main protease.

29 Mar 2022

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.

29 Mar 2022

NTU-developed coating for probiotics ensures effective delivery of beneficial bacteria into the intestine

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed probiotics with a unique edible coating that ensures the beneficial bacteria successfully reach the intestine once they are ingested.

25 Mar 2022

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

A new study has focussed on screening and identification of possible SMIs of this PPI for COVID-19.

25 Mar 2022

Researchers identify microbial cooperation as one of the causes of drug tolerance

The treatment of fungal infections is often hampered by fungal pathogens that do not respond, or are tolerant, against anti-fungal drugs.

23 Mar 2022

The obstacles to developing high-throughput 3D wound healing models

In this interview, News-Medical talks to Dr. Glauco Souza and Linda Boekestijn about their work in the wound healing space and how they devised a new high throughput 3D model for would healing.

From PromoCell 22 Mar 2022

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

Researchers reported a hybrid approach comprising computational models and high throughput screening to discover allosteric ACE2 binders inhibiting viral replication without interrupting ACE2 renal, pulmonary, immune, and cardiovascular functions.

22 Mar 2022

New test greatly simplifies the diagnosis of allergies

Although allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not always clear.

21 Mar 2022

The importance of the endosomal pathway for SARS-CoV-2 entry

Researchers demonstrated that combined inhibition of cell-surface-based and endosomal pathways completely blocked SARS-CoV-2 entry into mammalian cells.

21 Mar 2022

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

New research from Mayo Clinic's Center for Individualized Medicine finds that patients with ASXL1-mutant chronic myelomonocytic leukemia - an uncommon type of cancer of the bone marrow - have distinctive epigenetic changes that can activate harmful genes and cause the cancer to grow faster.

18 Mar 2022

Clinical utility of Roche assays determined utilizing samples from participants enrolled in a phase 2 trial of the mRNA-1273 vaccine

Researchers quantified the humoral immune response against the mRNA-1273 COVID-19 vaccine using commercially available high throughput assays.

17 Mar 2022

High Throughput News and Research

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Study identifies a new class of monoclonal antibodies that neutralize both alpha and beta coronaviruses

A summary of SARS-CoV-2 RNA-protein interactome studies

Immunity against SARS-CoV-2 BA.1, BA.2, and BA.3 after three doses of BNT162b2 vaccine

Study shows potential inhibition of SARS-CoV-2 main protease by natural phytochemicals

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

NTU-developed coating for probiotics ensures effective delivery of beneficial bacteria into the intestine

Study finds methylene blue is a low-micromolar inhibitor of the the SARS-CoV-2 spike protein and ACE2 interaction

Researchers identify microbial cooperation as one of the causes of drug tolerance

The obstacles to developing high-throughput 3D wound healing models

Angiotensin-converting enzyme 2 allosteric binders found to be effective against SARS-CoV-2

New test greatly simplifies the diagnosis of allergies

The importance of the endosomal pathway for SARS-CoV-2 entry

New discovery points to potential drug targets for ASXL1-mutant chronic myelomonocytic leukemia

Clinical utility of Roche assays determined utilizing samples from participants enrolled in a phase 2 trial of the mRNA-1273 vaccine

Lateral flow assays: The possibilities beyond COVID-19

Transcription factors work together to drive cancer cell proliferation

SARS-CoV-2 infection model generated from human tonsil epithelial organoids

Sustainable material-based biosensors for SARS-CoV-2 detection

In silico screening and testing of FDA approved drugs inhibiting SARS-CoV-2 spike protein cleavage

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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