Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

New adoptive T cell therapies - in which T cells, the immune system's natural hunters patrolling the body for foreign adversaries, are retrieved from cancer-riddled patients, super-charged and amplified outside the body, and then infused back into the same patient - are changing the prospects of cancer patients.

10 Feb 2023

Recent therapeutic strategies for renal cell carcinoma and the effects of the tumor microenvironment on systemic therapy

Researchers explored the association between the human microbiome and improved renal cell carcinoma outcomes.

6 Feb 2023

What are the predictors of in-hospital mortality in cancer patients with COVID-19?

A new study in PLoS ONE aimed to analyze the variables associated with in-hospital mortality in COVID-19-positive cancer patients who were presented to the ED.

3 Feb 2023

Experts discover mechanism of recruitment for tumor-associated cells in lung adenocarcinoma

A team of experts from the University of Barcelona, the University of Zaragoza and Hospital Clínic de Barcelona found a mechanism of recruitment for tumour-associated cells (cancer-associated fibroblasts or CAFs) which are essential to lung adenocarcinoma, the most frequent type of cancer.

31 Jan 2023

New nanomedicine delivery system offers some hope for treating peritoneal cancer

Peritoneal cancer is difficult to treat and has a poor survival prognosis. But a new and effective nanomedicine delivery system is offering some hope.

31 Jan 2023

Actin influences cancer metastases in many ways

Metastases occur when cancer cells leave a primary tumor and spread throughout the body. For this, they have to break connections with neighboring cells and migrate to other tissues.

31 Jan 2023

Using systems biology research to alter the properties of carcinogenic cells in the lungs

KAIST (President Kwang Hyung Lee) announced on January 30th that a research team led by Professor Kwang-Hyun Cho from the Department of Bio and Brain Engineering succeeded in using systems biology research to change the properties of carcinogenic cells in the lungs and eliminate both drug resistance and their ability to proliferate out to other areas of the body.

29 Jan 2023

Activated neutrophils can become potent cancer fighters

Elevated levels of immune cells, called neutrophils, in tumors have been associated with poor outcomes in people with cancer.

27 Jan 2023

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

Microtubules are cellular fibres that are part of the skeleton of the cell, termed cytoskeleton. They ensure that cells maintain their shape, carry out their functions, and divide.

27 Jan 2023

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

In this interview, News-Medical spoke to Dr. Jeremy Carlton and Professor Victoria Sanz-Moreno about their latest research into the spread of skin cancer.

20 Jan 2023

Understanding the mechanisms involved in heart disease and cancers

In a crucial step towards understanding the mechanisms involved in cardiovascular disease and certain cancers, a Canadian led research team has succeeded in a world first: they've found the molecular mechanism by which the protein PCSK9 degrades the receptor of low density lipoproteins, the richest cholesterol particles in the bloodstream.

19 Jan 2023

New Pyk2-derived peptide inhibits breast cancer metastasis

An estimated ninety percent of deaths from breast cancer are due to complications resulting from metastasis, a process in which cancer cells break away from where they first formed, travel through the blood or lymph circulatory system, and form new, metastatic tumors in other parts of the body.

17 Jan 2023

New molecular pathway critical to the initiation of pancreatic tumors discovered

Researchers at University of California San Diego School of Medicine have discovered a molecular pathway critical to the initiation of pancreatic tumors.

16 Jan 2023

Bacteria play specific roles in cancer

In a recent article published in the journal Immunity, the authors discussed the findings from a 2022 study by Galeano Niño et al., which reported that microbiota associated with tumors form micro-niches and play a role in epithelial and immune mediations of cancer.

12 Jan 2023

Physicists explore mesenchymal migration through cell simulations and mathematical modeling

During mesenchymal migration, a cancer cell moves like a gecko on a wall.

11 Jan 2023

Ringlike peripheral high iodine concentration for differentiating pulmonary metastasis from lung cancer

According to an accepted manuscript published in ARRS' American Journal of Roentgenology (AJR), ringlike peripheral high iodine concentration maps from dual-energy CT (DECT) can help guide management in patients with known lung cancer and an indeterminate solitary nodule.

11 Jan 2023

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

Researchers discovered that the elevated expression of LAP1, an inner nuclear membrane protein, helps metastatic melanoma cells surmount the physical challenges presented by tissue structure and the microenvironment during metastasis.

11 Jan 2023

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

In a recent study posted to the medRxiv* preprint server, researchers in the United Kingdom investigated lncRNA (long non-coding ribonucleic acids) expression in coronavirus disease 2019 (COVID-19) T lymphocyte transcriptomes.

10 Jan 2023

Researchers discover a protein that makes melanoma more aggressive

Research led by Queen Mary University of London, King's College London and the Francis Crick Institute has identified a protein that makes melanoma, the most serious type of skin cancer, more aggressive by giving cancer cells the ability to change the shape of their nucleus – a characteristic which allows the cells to migrate and spread around the body.

9 Jan 2023

Study uncovers molecular features responsible for the development, progression of metastatic breast cancer

A multi-institutional national study has identified unique molecular features responsible for the development and progression of metastatic breast cancer.

9 Jan 2023

Metastasis News and Research

Further Reading

Personalizing CAR-T cell stimulation during manufacturing can enhance its functionality

Recent therapeutic strategies for renal cell carcinoma and the effects of the tumor microenvironment on systemic therapy

What are the predictors of in-hospital mortality in cancer patients with COVID-19?

Experts discover mechanism of recruitment for tumor-associated cells in lung adenocarcinoma

New nanomedicine delivery system offers some hope for treating peritoneal cancer

Actin influences cancer metastases in many ways

Using systems biology research to alter the properties of carcinogenic cells in the lungs

Activated neutrophils can become potent cancer fighters

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

Metastatic Melanoma: key protein identified that aids the spread of skin cancer

Understanding the mechanisms involved in heart disease and cancers

New Pyk2-derived peptide inhibits breast cancer metastasis

New molecular pathway critical to the initiation of pancreatic tumors discovered

Bacteria play specific roles in cancer

Physicists explore mesenchymal migration through cell simulations and mathematical modeling

Ringlike peripheral high iodine concentration for differentiating pulmonary metastasis from lung cancer

Study identifies LAP1 as a master regulator of nuclear envelope remodeling during melanoma progression

MALAT1 suppression is a hallmark of tissue and peripheral proliferative T cells in COVID-19

Researchers discover a protein that makes melanoma more aggressive

Study uncovers molecular features responsible for the development, progression of metastatic breast cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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