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UVA researchers find way to enhance cancer outcomes by examining patients' genetic data

By mining a vast trove of genetic data, researchers at the University of Virginia School of Medicine are enhancing doctors’ ability to treat cancer, predict patient outcomes and determine which treatments will work best for individual patients.

30 Mar 2020

Study finds promising biomarker for diagnosis of schizophrenia and treatment response

Around four in a thousand people worldwide suffer from schizophrenia, according to scientific estimates. The disease affects people from all walks of life, including Vincent van Gogh, the painter Agnes Martin, mathematician John Nash and Eduard Einstein, a son of the great physicist. The disease touches men and women equally.

23 Mar 2020

Overview of prognostic and predictive factors in pancreatic cancer

Oncotarget Volume 11, Issue 10 reported that there are not standardized predictive biomarkers able to identify patients who benefit most from treatments.

13 Mar 2020

New collapsible basket technology has big advantages for drug discovery, personalized medicine

A drug discovery scientist typically screens up to 10,000 compounds in the early stages of developing one FDA approved drug. During this high-throughput screening, candidate compounds are initially tested on cell and tissue samples.

4 Mar 2020

Personalized approach in IVF increases success rate

Becoming pregnant can be a lengthy and stressful process for one in every six couples. As fertility treatment protocols are based on the "average woman", approximately 30 per cent of patients need a personalised approach in IVF.

4 Mar 2020

Challenges for translating pharmacomicrobiomics to personalized medicine

A new Commentary identifies three actionable challenges for translating pharmacomicrobiomics to personalized medicine in 2020.

2 Mar 2020

WFIRM scientists develop miniature organ model to test drug toxicity

Scientists at the Wake Forest Institute for Regenerative Medicinehave developed the world's most sophisticated laboratory model of the human body, creating a system of miniaturized organs that can be used to detect harmful and adverse effects of drugs before they are prescribed to patients.

2 Mar 2020

New research cluster aims to use mass spectrometry to provide insights in systems medicine

The Mainz University Medical Center and Johannes Gutenberg University Mainz are establishing the interdisciplinary research cluster entitled "Data-Independent Acquisition-based Systems Medicine (DIASyM): Mass Spectrometry for High-Throughput Deep Phenotyping of Heart Failure Syndrome".

28 Feb 2020

Coriell researchers find new genetic indicator of obesity risk

Obesity is among the most common complex diseases in the United States and has been a stubborn public health challenge for decades. Its causes are wide ranging, but genetic heritability is increasingly understood to be an influential factor in determining a person's risk for the disease.

23 Feb 2020

Association between HMO concentrations and infant weight, body composition

Breastfeeding affects infant growth and, researchers have found, helps prevent obesity, both in childhood and later in life. However, the components of breast milk responsible for these beneficial effects remain mostly a mystery.

18 Feb 2020

Detailed maps of breast cancer reveal how genetic changes shape the tumor landscape

Scientists have created one of the most detailed maps of breast cancer ever achieved, revealing how genetic changes shape the physical tumor landscape, according to research funded by Cancer Research UK and published in Nature Cancer today (Monday).

17 Feb 2020

Revolutionary SPion technology enables remote analysis with mass spectrometry

Trace Matters Scientific today introduced SPion -a revolutionary technology that enables the world's most sensitive and versatile remote analysis with mass spectrometry.

16 Feb 2020

Study provides a detailed molecular snapshot of endometrial cancer

A study published Feb. 13 in Cell provides an unprecedented look at the dozens of molecular steps that occur to bring about endometrial cancer, commonly known as uterine cancer.

14 Feb 2020

Treating soft tissue sarcoma with shorter radiation treatment found to be safe, effective

A new study led by researchers at the UCLA Jonsson Comprehensive Cancer Center found that treating soft tissue sarcoma with radiation over a significantly shorter period of time is safe, and likely just as effective, as a much longer conventional course of treatment.

13 Feb 2020