Transplant News and Research

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Contact lens solution found to cause serious infection

The Food and Drug Administration (FDA) in the United States has issued a warning to health care professionals and consumers regarding a certain contact lens solution.

27 May 2007

Stem cells may look malignant, not act it

Call it the cellular equivalent of big glasses, a funny nose and a fake mustache.

24 May 2007

Study of VentrAssist heart support device as a bridge to transplantation

Doctors at UPMC have begun a study using an investigational cardiac device, the VentrAssist, Left Ventricular Assist System (LVAD) to see whether it can be used safely and effectively in patients with end-stage heart failure.

23 May 2007

Cure for hepatitis C

The use of peginterferon alone, or in combination with ribavirin, points to a cure for hepatitis C, the leading cause of cirrhosis, liver cancer and the need for liver transplant, a Virginia Commonwealth University researcher said today.

22 May 2007

First beating heart transplant procedure in the US

Protected by its own nutrients and blood supply, a beating heart supported by an investigational organ preservation device was successfully transplanted into a 47-year-old man with congestive heart failure and pulmonary hypertension on Sunday, April 8.

18 May 2007

Custom-designed contacts improve vision for subjects with keratoconic eyes

Keratoconic eyes are rare but disabling. From the side, the eyes look more pointed or cone-shaped than round. The apex shift from visual axis in the cornea causes people with the condition to see halos and double and triple images. About 1 in 2,000 people suffer from the disease, usually in both eyes.

18 May 2007

Transforming kidney transplant policy

A new article published in American Journal of Transplantation examines the dilemmas faced in trying to change kidney transplant policy; addressing the need to balance the benefits of immediate transplants with those to be had from waiting for a more suitable match.

18 May 2007

Glucose plays a key role in enabling healthy beta cells

A key aspect of how embryos create the cells which secrete insulin is revealed in a new study published in the Journal of Biological Chemistry.

18 May 2007

Surgeons rebuild war veteran's nose using his own body parts

It took only seconds for the Humvee to flip over and crash on a highway near Camp Bucca in southern Iraq in August 2005.

17 May 2007

Complement receptor 3 sends a signal to dampen the immune system

Researchers from The Children's Hospital of Philadelphia and The University of Pennsylvania reported that complement receptor 3 (CR3), a protein found on cell surfaces, inhibits dendritic cells, the sentinels of the immune system, from setting off an alarm signal that brings on a full immune response.

16 May 2007

Researchers identify human genes targeted by a virus believed to cause Kaposi's sarcoma

University of Florida researchers have identified specific human genes targeted by a virus believed to cause Kaposi's sarcoma, a rare form of cancer associated with AIDS and with organ transplants that causes patches of red or purple tissue to grow under people's skin.

11 May 2007

Breakthrough on cytomegalovirus transmission

Researchers at the La Jolla Institute for Allergy & Immunology have shown that cytomegalovirus (CMV) in the salivary glands can be reduced , and in some cases eliminated , through the use of antibodies to enhance the disease-fighting power of the immune system.

11 May 2007

CT and MRI are highly accurate at determining which patients would be optimal candidates for liver transplantation

CT and MRI are highly accurate at determining which patients would be optimal candidates for liver transplantation, says a recent study.

11 May 2007

Contrast-enhanced ultrasound after liver transplant is highly accurate in showing vascular as well as biliary complications

The study consisted of 39 liver transplant recipients who underwent a CE-US exam after developing fluid in the abdomen and/or unclear liver function tests.

8 May 2007

Adult stem cells play no role in insulin production

Diabetes researchers, investigating how the body supplies itself with insulin, discovered to their surprise that adult stem cells, which they expected to play a crucial role in the process, were nowhere to be found.

8 May 2007

Study evaluates why blacks do not successfully donate kidneys

In one of the first studies of its kind, researchers from Wake Forest University School of Medicine explored why blacks are less likely than other races to become living kidney donors, and the reasons are obesity and failure to complete the donor evaluation.

8 May 2007

New compounds promising candidates for neurodegenerative disease drug development

Scientists have developed a novel strategy for tackling neurodegenerative diseases such as Huntington's disease: encouraging an individual's own cells to "eat" the malformed proteins that lead to the disease.

8 May 2007

Heart-assist devices may help some end-stage heart failure patients avoid transplant

Implanted pumps improved heart function enough in a small percentage of patients awaiting a heart transplant that they were able to leave the hospital without a pump and without a new heart, according to a study in Circulation: Journal of the American Heart Association.

8 May 2007

Machine preservation may promote more organ sharing

Preserving the kidneys of deceased older donors on a pump, as opposed to the conventional method of storing and transporting organs in a cooler, may lower hospital costs, improve initial organ function, and promote greater use and more sharing of organs, according to new research by Wake Forest University Baptist Medical Center.

4 May 2007