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Intestinal flora likely to have effect on person's response to drugs

Intestinal flora has multiple influences on human health, but researchers have revealed that it is also likely to have an effect on the body's response to drugs.

12 Aug 2016

Study provides detailed picture of genetics underlying type 2 diabetes

The largest study of its kind into type 2 diabetes has produced the most detailed picture to date of the genetics underlying the condition.

12 Aug 2016

Hygiene hypothesis: a misleading misnomer? An interview with Professor Sally Bloomfield

Professor Strachan first proposed the hygiene hypothesis back in 1989. Reviewing the evidence, he suggested that one of the causes of the recent rapid rise in allergic diseases in children was lack of exposure to childhood infections

11 Aug 2016

RNA silencing technique developed by spinoff from UM-Madison effective in battling hepatitis B

A method for "silencing" RNA that emerged from a University of Wisconsin-Madison spinoff company is in clinical trials in Europe, Asia and the United States against hepatitis B, an infection that can destroy the liver.

11 Aug 2016

Researchers examine different dietary approaches to help improve nutrition for poor in Zambia

Over the past several decades in Zambia, data from the Food and Agriculture Organization of the United Nations show that there has been a decrease in the per capita consumption of milk, meat, and eggs and an increase in starchy roots, primarily cassava.

11 Aug 2016

New disease gene linked to shortened telomeres appears to raise risk of pulmonary fibrosis-emphysema

Johns Hopkins researchers say they have identified a new disease gene that, when mutated, appears to increase the risk in a small number of people of developing emphysema and a lung-scarring condition known as pulmonary fibrosis.

10 Aug 2016

New technology uses natural nano-scale lipid transport system to deliver drugs straight to bloodstream

For years scientists and dieticians have argued over the health benefits of dietary fat. Research published this week, however, shows that piggybacking onto natural fat absorption pathways can dramatically enhance the utility of some drugs.

10 Aug 2016

SBP researchers discover potential drug target for treatment of type 2 diabetes

Researchers at the Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a new potential target for drugs to prevent type 2 diabetes. A paper published today in the Journal of Clinical Investigation shows that blocking a cellular glucose sensor in muscle improves insulin responsiveness.

10 Aug 2016

Rare genetic variations linked to severe porphyria

An international research team has linked rare variations in a cell membrane protein to the wide variation in symptom severity that is a hallmark of porphyria, a rare disorder that often affects the skin, liver and nervous system.

10 Aug 2016

Researchers uncover how GWAS-implicated gene affects HDL-cholesterol levels

Researchers have uncovered how genes identified from genome-wide association studies (GWAS) affect high-density lipoprotein cholesterol (HDL-C), a biomarker of cardiovascular disease, after comparing several animal models with human patient data.

10 Aug 2016

Researchers develop computational algorithm to analyze big genomic data for different cancers

University of Hawai'i Cancer Center researchers developed a computational algorithm to analyze "Big Data" obtained from tumor samples to better understand and treat cancer.

10 Aug 2016

Researcher receives grant to study how changes in gut bacteria could lead to obesity-related disorders

Andrew Gewirtz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a four-year, $1.8-million federal grant to study how changes in intestinal bacteria could lead to obesity and metabolic syndrome.

9 Aug 2016

Researchers uncover new preventative way to battle against Ascaris roundworm infection

Scientists working out of Trinity College Dublin, Maynooth University, and Queen Mary University of London have unearthed a potential new preventative option to combat Ascaris roundworm infection.

8 Aug 2016

Naturally-occurring protein controls shape and activity of white blood cells to combat sepsis

Boosting levels of a protein that controls the shape and activity of a crucial group of white blood cells improves survival and recovery chances during sepsis.

8 Aug 2016

Immunotherapy innovations in oncology: an interview with Robert LaCaze

The body’s immune system is an excellent weapon against many diseases. For more than 100 years, immunology and immunotherapy have played an ever-increasing role in the understanding and treatment of cancer.

8 Aug 2016

Clinics with comprehensive care for premature infants alleviate concerns for parents

On January 24, 2013, Iris Vega-Figueroa's life changed completely. That's the day she gave birth to her twin girls, Iris and Geraldine. The twins were monoamniotic-monochorionic, meaning they shared one amniotic sack and one placenta in the womb. These rare pregnancies are considered high risk because of the uneven blood flow that occurs between the infants through the placenta.

8 Aug 2016

Increased treatment for HCV in Rhode Island could help eradicate disease by 2030

A new Brown University study projects that increasing the number of Rhode Islanders treated every year for hepatitis C virus infection (HCV) to about 2,000 by 2020 would reduce cases by 90 percent and prevent more than 70 percent of expected liver-related deaths in the state by 2030.

5 Aug 2016

Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

Studies have shown that obstructive sleep apnea and low nighttime oxygen, which result in oxidative stress, are associated with the progression of non-alcoholic fatty liver disease (NAFLD) in adults.

5 Aug 2016

Research could help develop better therapies for new subtype of adenocarcinoma patients

Lung cancer is the most common cause of cancer deaths, accounting for about a third of all tumor-related deaths. Adenocarcinomas, a non-small cell lung cancer (NSCLC), account for about 40 percent of cancer diagnoses, but few treatments are available for the disease.

4 Aug 2016

Naturally occurring estrogen in cow’s milk does not affect blood hormone levels, study shows

Estrogen occurs naturally in cow's milk. Recently, there has been concern that consuming milk containing elevated amounts of estrogen could affect blood levels of the hormone in humans, leading to an increased risk of some cancers.

3 Aug 2016

Liver News and Research

Intestinal flora likely to have effect on person's response to drugs

Study provides detailed picture of genetics underlying type 2 diabetes

Hygiene hypothesis: a misleading misnomer? An interview with Professor Sally Bloomfield

RNA silencing technique developed by spinoff from UM-Madison effective in battling hepatitis B

Researchers examine different dietary approaches to help improve nutrition for poor in Zambia

New disease gene linked to shortened telomeres appears to raise risk of pulmonary fibrosis-emphysema

New technology uses natural nano-scale lipid transport system to deliver drugs straight to bloodstream

SBP researchers discover potential drug target for treatment of type 2 diabetes

Rare genetic variations linked to severe porphyria

Researchers uncover how GWAS-implicated gene affects HDL-cholesterol levels

Researchers develop computational algorithm to analyze big genomic data for different cancers

Researcher receives grant to study how changes in gut bacteria could lead to obesity-related disorders

Researchers uncover new preventative way to battle against Ascaris roundworm infection

Naturally-occurring protein controls shape and activity of white blood cells to combat sepsis

Immunotherapy innovations in oncology: an interview with Robert LaCaze

Clinics with comprehensive care for premature infants alleviate concerns for parents

Increased treatment for HCV in Rhode Island could help eradicate disease by 2030

Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

Research could help develop better therapies for new subtype of adenocarcinoma patients

Naturally occurring estrogen in cow’s milk does not affect blood hormone levels, study shows

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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