Therapeutics News and Research

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MIT researchers devise new strategy to make tumor cells more susceptible to cancer treatment

MIT researchers have devised a way to make tumor cells more susceptible to certain types of cancer treatment by coating the cells with nanoparticles before delivering drugs.

20 Mar 2017

Novel synthetic HDL-C injection shows no benefit on arterial plaques

Injection of a novel form of synthetic high-density lipoprotein cholesterol (HDL-C), or good cholesterol, into the arteries of patients who had recently had a heart attack did not reduce the volume of fatty deposits, or plaque, in the arteries, compared with placebo injections, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

First physiological test opens door to early diagnosis of autism

An algorithm based on levels of metabolites found in a blood sample can accurately predict whether a child is on the Autism spectrum of disorder (ASD), based upon a recent study.

16 Mar 2017

TSRI researchers develop novel drug delivery method for treating cancers

Scientists from the Florida campus of The Scripps Research Institute have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors.

16 Mar 2017

University of Liverpool to establish new research centre to accelerate development of novel antibiotics

A state-of-the-art research centre to help accelerate the development of new antibiotics is set to be established by the University of Liverpool.

16 Mar 2017

Research shows how Ebola viral proteins packaged in exosomes affect immune cells

Cells infected by the deadly Ebola virus may release viral proteins such as VP40 packaged in exosomes, which, as new research indicates, can affect immune cells throughout the body impairing their ability to combat the infection and to seek out and destroy hidden virus.

16 Mar 2017

Frequent interactions with family members can impact age of autism diagnosis, research reveals

Children who have older siblings or frequent interaction with grandparents are diagnosed with autism spectrum disorders (ASD) earlier than those who do not, according to new research conducted at The Seaver Autism Center for Research and Treatment at Mount Sinai, and published in the journal Autism.

15 Mar 2017

LJI researchers unravel molecular underpinnings of exhausted T cells

One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells.

15 Mar 2017

Researchers make surprising and crucial discovery about Alexander disease

Researchers at the University of Wisconsin-Madison have made a surprising and potentially crucial discovery about Alexander disease, a rare and fatal neurological disorder with no known cure.

15 Mar 2017

Bacterial cell counting and sizing using the Multisizer

In this interview, Dr. Rich Jones introduces bacterial cell counting and an example of when the Multisizer 4e from Beckman Coulter has been used for this application.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 15 Mar 2017

Drug combination delivered by nanoparticles may keep melanoma from becoming resistant to treatment

The first of a new class of medication that delivers a combination of drugs by nanoparticle may keep melanoma from becoming resistant to treatment, according to Penn State College of Medicine researchers.

15 Mar 2017

Low levels of allopregnanolone hormone may predict risk of postpartum depression

In a small-scale study of women with previously diagnosed mood disorders, Johns Hopkins researchers report that lower levels of the hormone allopregnanolone in the second trimester of pregnancy were associated with an increased chance of developing postpartum depression in women already known to be at risk for the disorder.

14 Mar 2017

Defect in non-coding DNA could give rise to language impairments in children

The human genome is made up of ~3 billion letters of DNA and at each position it is possible to have different letters, called variants. Some variants are harmless but others can be detrimental, making it a mammoth task to find out which variants cause a disorder.

14 Mar 2017

Pill form of C-diff treatment could be effective, easier for patients and physicians, study shows

Frozen and freeze-dried products for Fecal Microbiota Transplantation are nearly as effective as fresh product at treating patients with Clostridium difficile infection, according to researchers at The University of Texas Health Science Center at Houston School of Public Health and Kelsey Research Foundation.

14 Mar 2017

New technique opens door for biochemists to create better therapeutic antibodies

Antibodies are the foot soldiers of our immune system. These specialized, Y-shaped proteins attach to bacteria and viruses, where they either block the pathogen's activity directly, or signal the immune system's cells to destroy the invader.

14 Mar 2017

Researchers explore genomic underpinnings of obesity in continental Africans and African-Americans

An international team of researchers has conducted the first study of its kind to look at the genomic underpinnings of obesity in continental Africans and African-Americans.

13 Mar 2017

Endostatin can decrease proliferation of castration-resistant prostate cancer cells

Failure of hormone deprivation therapy, which is used to slow prostate cancer in patients, leads to castration-resistant prostate cancer, a lethal form of advanced disease with limited treatment options.

10 Mar 2017

Researchers take important step forward in disabling cancer cells' defences

Recent study out of the University of Ottawa opens door for new disease therapies in cancer, ALS, Fragile X Syndrome and others.

10 Mar 2017

Drug could activate innate anti-tumor immunity to eradicate aggressive prostate cancer in mice

Cabozantinib, a drug already used to treat patients with certain types of thyroid or kidney cancer, was able to eradicate invasive prostate cancers in mice by causing tumor cells to secrete factors that entice neutrophils - the first-responders of the immune system - to infiltrate the tumor, where they triggered an immune response that led to tumor clearance.

9 Mar 2017

Precision NanoSystems launches NanoAssemblr Scale-Up system to support production of novel medicines

Precision NanoSystems has launched the NanoAssemblr™ Scale-Up system to support the clinical development of nanomedicines.

From Precision NanoSystems Inc. 9 Mar 2017

Therapeutics News and Research

MIT researchers devise new strategy to make tumor cells more susceptible to cancer treatment

Novel synthetic HDL-C injection shows no benefit on arterial plaques

First physiological test opens door to early diagnosis of autism

TSRI researchers develop novel drug delivery method for treating cancers

University of Liverpool to establish new research centre to accelerate development of novel antibiotics

Research shows how Ebola viral proteins packaged in exosomes affect immune cells

Frequent interactions with family members can impact age of autism diagnosis, research reveals

LJI researchers unravel molecular underpinnings of exhausted T cells

Researchers make surprising and crucial discovery about Alexander disease

Bacterial cell counting and sizing using the Multisizer

Drug combination delivered by nanoparticles may keep melanoma from becoming resistant to treatment

Low levels of allopregnanolone hormone may predict risk of postpartum depression

Defect in non-coding DNA could give rise to language impairments in children

Pill form of C-diff treatment could be effective, easier for patients and physicians, study shows

New technique opens door for biochemists to create better therapeutic antibodies

Researchers explore genomic underpinnings of obesity in continental Africans and African-Americans

Endostatin can decrease proliferation of castration-resistant prostate cancer cells

Researchers take important step forward in disabling cancer cells' defences

Drug could activate innate anti-tumor immunity to eradicate aggressive prostate cancer in mice

Precision NanoSystems launches NanoAssemblr Scale-Up system to support production of novel medicines

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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