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Lactate-producing intratumoral bacteria drive resistance to radiation therapy

Researchers at The University of Texas MD Anderson Cancer Center have discovered that lactate-producing intratumoral bacteria drives resistance to radiation therapy, suggesting that lactic acid-producing bacteria present in various cancers may serve as novel therapeutic targets.

19 Oct 2023

CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Patients with multiple myeloma treated with idecabtagene vicleucel, known as "ide-cel," a chimeric antigen receptor (CAR) T-cell therapy, had no difference in overall survival outcomes regardless of race and ethnicity, according to a study published in Blood Advances.

19 Oct 2023

Researchers profile new drug combinations to fight antibiotic-resistant bacteria

Antimicrobial resistance – occurring when pathogens can survive antibiotic treatment – is one of the most rapidly emerging global public health threats today.

19 Oct 2023

Common challenges when seeking market access for rare disease therapies

In this interview, News Medical speaks to Donovan Quill, Executive Vice President of Growth & Strategy at AscellaHealth about the recurring challenges met when seeking market access for rare disease therapies.

From AscellaHealth, LLC. 19 Oct 2023

Can selenium and vitamin E supplementation prevent recurrence and progression of non–muscle-invasive bladder cancer?

The use of vitamin E and selenium in preventing the recurrence and progression of NMIBC.

19 Oct 2023

Blue light technology to combat surface contamination by foodborne pathogens

How effectively antimicrobial blue light (aBL) inactivated dried cells and biofilms.

19 Oct 2023

How does diet impact rosacea and acne?

The associations between diet, rosacea, and acne.

19 Oct 2023

How the gut microbiome contributes to schizophrenia

Researchers explore potential relationships between schizophrenia, the gut microbiome, the gut-brain axis, and short-chain fatty acids.

19 Oct 2023

How do different organ microbiomes influence neuropsychiatric disorders?

Scientists review existing literature to understand how the microbiome influences neuropsychiatric disorders.

19 Oct 2023

New model helps to better understand how Alzheimer's disease progresses in the brain

A new model developed by Van Andel Institute, Lund University and University of Florence scientists will enable researchers to better understand how Alzheimer's disease progresses in the brain.

18 Oct 2023

Pan-coronavirus vaccine shows success in mouse studies

A vaccine designed to protect against three different deadly coronaviruses shows success in mouse studies, demonstrating the viability of a pan-coronavirus vaccine developed by researchers at the Duke Human Vaccine Institute.

18 Oct 2023

Chan Zuckerberg Initiative launches new biomedical research hub to build technologies for improving health

Today, the Chan Zuckerberg Initiative (CZI) announced the launch of a new biomedical research hub in New York City that will catalyze collaboration between leading scientific and technology institutions in the area, with the goal of solving grand scientific challenges on 10- to 15-year time horizons.

18 Oct 2023

Study sheds light on how NAD+ levels decline with age in the ovaries, affecting fertility

A woman's fertility normally decreases by her late 30s with reproductive function eventually ceasing at menopause.

18 Oct 2023

Microscale device for eye implantation may be used in the treatment of diabetes

Researchers in Sweden have developed a microscale device for implantation in the eye, which presents new opportunities for cell-based treatment of diabetes and other diseases.

18 Oct 2023

Greenspace exposure has positive impact on telomere length, study finds

A new study finds that greenspace – the vegetation in a neighborhood's yards, parks and public spaces – has a positive impact on a key genetic marker associated with exposure to stress.

18 Oct 2023

Children's immune system better prepared to defend against SARS-CoV-2, study finds

Why are severe courses of SARS-CoV-2 infection much less common in children and adolescents than in adults? Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now discovered that the immune system in the upper respiratory tract is much more alert and active in children before infection than in adults and is therefore better equipped to fight the virus.

18 Oct 2023

Research suggests a potential new approach for halting the spread of pancreatic cancer

A new study carried out in mice, led by Queen Mary University of London, has identified cells that drive the spread of pancreatic cancer and discovered a weakness in these cells that could be targeted using existing drugs.

18 Oct 2023

Lung chip model offers new insights into how radiation damages the lungs

The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis.

17 Oct 2023

Kidney transplantation turns back the clock on renal aging

This recent study in the Journal of Internal Medicine reveals that kidney transplantation mitigates the effects of renal aging in chronic kidney disease patients, outperforming dialysis. The research utilized DNA methylation clocks to assess biological age, finding that age acceleration decreased one year post-transplant but remained unchanged with dialysis.

17 Oct 2023

New treatment options offer hope for patients with non-small cell lung cancer

More people with non-small cell lung cancer (NSCLC) are likely to benefit from new drugs that target molecular alterations in tumour cells, with less need for chemotherapy, following results of multiple landmark clinical trials reported for the first time in late-breaking presentations at the ESMO Congress 2023 (1-7).

17 Oct 2023

B Cell News and Research

Lactate-producing intratumoral bacteria drive resistance to radiation therapy

CAR T-cell therapy for multiple myeloma shows no difference in survival outcomes by race and ethnicity

Researchers profile new drug combinations to fight antibiotic-resistant bacteria

Common challenges when seeking market access for rare disease therapies

Can selenium and vitamin E supplementation prevent recurrence and progression of non–muscle-invasive bladder cancer?

Blue light technology to combat surface contamination by foodborne pathogens

How does diet impact rosacea and acne?

How the gut microbiome contributes to schizophrenia

How do different organ microbiomes influence neuropsychiatric disorders?

New model helps to better understand how Alzheimer's disease progresses in the brain

Pan-coronavirus vaccine shows success in mouse studies

Chan Zuckerberg Initiative launches new biomedical research hub to build technologies for improving health

Study sheds light on how NAD+ levels decline with age in the ovaries, affecting fertility

Microscale device for eye implantation may be used in the treatment of diabetes

Greenspace exposure has positive impact on telomere length, study finds

Children's immune system better prepared to defend against SARS-CoV-2, study finds

Research suggests a potential new approach for halting the spread of pancreatic cancer

Lung chip model offers new insights into how radiation damages the lungs

Kidney transplantation turns back the clock on renal aging

New treatment options offer hope for patients with non-small cell lung cancer

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